CRCGN016_MCF10A.TP53.M_24H:B06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TCEA2 transcription elongation factor A (SII), 2 4.50749
CCDC85B coiled-coil domain containing 85B 3.08731
MAMLD1 mastermind-like domain containing 1 2.91851
WDR7 WD repeat domain 7 2.52594
EPN2 epsin 2 2.30528
TIAM1 T-cell lymphoma invasion and metastasis 1 2.29718
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.2634
ADRB2 adrenoceptor beta 2, surface 2.23462
FGFR4 fibroblast growth factor receptor 4 2.23132
TLCD3A TLC domain containing 3A 2.21895

decreased expression

Symbol Name Standardized Value
MT1X metallothionein 1X -3.16099
LAP3 leucine aminopeptidase 3 -3.14404
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.96557
ANKRD10 ankyrin repeat domain 10 -2.9422
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.69811
KRT14 keratin 14, type I -2.68937
PRCP prolylcarboxypeptidase (angiotensinase C) -2.52836
CD58 CD58 molecule -2.43326
CDK4 cyclin-dependent kinase 4 -2.37754
RBM34 RNA binding motif protein 34 -2.15266
HEATR1 HEAT repeat containing 1 -2.05901