CRCGN016_MCF10A.TP53.M_24H:B07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3',4,4'-tetrachloro-1,1'-biphenyl 95.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 3.4217
TP53BP2 tumor protein p53 binding protein 2 3.28493
CCNA1 cyclin A1 2.78926
CXCR4 chemokine (C-X-C motif) receptor 4 2.74521
SESN1 sestrin 1 2.18302
FBXL12 F-box and leucine-rich repeat protein 12 2.17609
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.06101

decreased expression

Symbol Name Standardized Value
COPS7A COP9 signalosome subunit 7A -3.7111
CDC25B cell division cycle 25B -2.67315
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.54878
COTL1 coactosin-like F-actin binding protein 1 -2.41985
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.35234
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.14035
PCCB propionyl CoA carboxylase, beta polypeptide -2.03131
RBM34 RNA binding motif protein 34 -2.01427