CRCGN016_MCF10A.TP53.M_24H:B08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3',4,4'-tetrachloro-1,1'-biphenyl 31.81 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 5.38341
KLHL21 kelch-like family member 21 5.19708
KCTD5 potassium channel tetramerization domain containing 5 4.69344
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.03285
KIF5C kinesin family member 5C 3.5511
TLCD3A TLC domain containing 3A 3.09324
DENND2D DENN/MADD domain containing 2D 2.1597
FAIM Fas apoptotic inhibitory molecule 2.05696
GSTZ1 glutathione S-transferase zeta 1 2.01412

decreased expression

Symbol Name Standardized Value
YME1L1 YME1-like 1 ATPase -4.16517
ZDHHC6 zinc finger, DHHC-type containing 6 -4.07423
SGK1 serum/glucocorticoid regulated kinase 1 -3.99694
FASTKD5 FAST kinase domains 5 -3.85231
TCEA2 transcription elongation factor A (SII), 2 -3.72362
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.47159
RALGDS ral guanine nucleotide dissociation stimulator -2.21386
MXI1 MAX interactor 1, dimerization protein -2.02904