CRCGN016_MCF10A.TP53.M_24H:B09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3',4,4'-tetrachloro-1,1'-biphenyl 10.6 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ACAA1 acetyl-CoA acyltransferase 1 3.31791
STK10 serine/threonine kinase 10 3.22987
AGR2 anterior gradient 2 2.57917
MELK maternal embryonic leucine zipper kinase 2.46276
GSTZ1 glutathione S-transferase zeta 1 2.46155
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.38445
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.37362
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.27863
COMP cartilage oligomeric matrix protein 2.26807
SOCS2 suppressor of cytokine signaling 2 2.01447

decreased expression

Symbol Name Standardized Value
OXA1L oxidase (cytochrome c) assembly 1-like -5.63884
HEATR1 HEAT repeat containing 1 -4.22475
NLRP4 NLR family, pyrin domain containing 4 -4.15798
CCNB2 cyclin B2 -3.59475
RPS5 ribosomal protein S5 -2.74216
PCCB propionyl CoA carboxylase, beta polypeptide -2.34986
TOR1A torsin family 1, member A (torsin A) -2.28849
DAD1 defender against cell death 1 -2.25971
RPL8 ribosomal protein L8 -2.03117
RPL18 ribosomal protein L18 -2.00101