CRCGN016_MCF10A.TP53.M_24H:B10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description chrysene 93.2 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INTS3 integrator complex subunit 3 5.07197
CARMIL1 capping protein regulator and myosin 1 linker 1 4.8755
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.31618
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.0583
CCDC85B coiled-coil domain containing 85B 2.8242
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.63176
MELK maternal embryonic leucine zipper kinase 2.31063
STK10 serine/threonine kinase 10 2.23678
WDR4 WD repeat domain 4 2.1496
CDT1 chromatin licensing and DNA replication factor 1 2.08092
E2F2 E2F transcription factor 2 2.02337
PRR7 proline rich 7 (synaptic) 2.01771
ZNF692 zinc finger protein 692 2.01134

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -5.04435
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.83144
TM9SF3 transmembrane 9 superfamily member 3 -4.44269
RPA3 replication protein A3, 14kDa -3.78215
TLK2 tousled-like kinase 2 -3.44106
TNIP1 TNFAIP3 interacting protein 1 -3.01931
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.51635
KIF14 kinesin family member 14 -2.3185
THADA thyroid adenoma associated -2.09722
IL10RB interleukin 10 receptor, beta -2.05744
SKP1 S-phase kinase-associated protein 1 -2.05508