CRCGN016_MCF10A.TP53.M_24H:B13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description TCDD-dioxin 0.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SQOR sulfide quinone oxidoreductase 2.9821
FGFR4 fibroblast growth factor receptor 4 2.47366
TBXA2R thromboxane A2 receptor 2.31953
MAP2K5 mitogen-activated protein kinase kinase 5 2.25801
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.17745
TRH thyrotropin-releasing hormone 2.17551
ACAA1 acetyl-CoA acyltransferase 1 2.11446
CLTC clathrin, heavy chain (Hc) 2.01297

decreased expression

Symbol Name Standardized Value
SGK1 serum/glucocorticoid regulated kinase 1 -5.03267
PCNA proliferating cell nuclear antigen -4.78563
CCNB1 cyclin B1 -4.74887
HMG20B high mobility group 20B -4.72345
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.81428
VDAC1 voltage-dependent anion channel 1 -3.76197
CTNND1 catenin (cadherin-associated protein), delta 1 -3.5475
ATG3 autophagy related 3 -2.74806
RALGDS ral guanine nucleotide dissociation stimulator -2.72879
LCN1 lipocalin 1 -2.24406
TXNDC15 thioredoxin domain containing 15 -2.0636