CRCGN016_MCF10A.TP53.M_24H:B14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description TCDD-dioxin 0.03 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.22424
C2CD2 C2 calcium-dependent domain containing 2 3.63733
UBQLN2 ubiquilin 2 3.47399
CXCR4 chemokine (C-X-C motif) receptor 4 3.00625
KLHL21 kelch-like family member 21 2.94983
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.88199
NOTCH1 notch 1 2.50563
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.49199
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.42529
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.29479
AGR2 anterior gradient 2 2.22215
ADAM10 ADAM metallopeptidase domain 10 2.20564
NRBF2 nuclear receptor binding factor 2 2.07584
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.0073

decreased expression

Symbol Name Standardized Value
ATG3 autophagy related 3 -2.21696
BAD BCL2-associated agonist of cell death -2.15929