| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | TCDD-dioxin 0.01 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOTCH1 | notch 1 | 5.01544 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 4.81631 |
| KDM5D | lysine (K)-specific demethylase 5D | 4.18469 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 4.03934 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.64729 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 3.4607 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 3.41397 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.95443 |
| TLCD3A | TLC domain containing 3A | 2.94246 |
| CADPS2 | Ca++-dependent secretion activator 2 | 2.88384 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 2.67803 |
| SLC61A1 | solute carrier family 61 member 1 | 2.44123 |
| TRAPPC4 | trafficking protein particle complex 4 | 2.37358 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.34622 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 2.34129 |
| NRBF2 | nuclear receptor binding factor 2 | 2.3253 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.30664 |
| BCOR | BCL6 corepressor | 2.29831 |
| ZFY | zinc finger protein, Y-linked | 2.19409 |
| PRSS22 | protease, serine, 22 | 2.14657 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 | 2.13171 |
| IGSF6 | immunoglobulin superfamily, member 6 | 2.13014 |
| NLGN4Y | neuroligin 4, Y-linked | 2.10143 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.09318 |
| EDN1 | endothelin 1 | 2.08581 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.06728 |
| HBA1 | hemoglobin, alpha 1 | 2.03065 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 2.02135 |
| IL23A | interleukin 23, alpha subunit p19 | 2.01511 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PARP2 | poly (ADP-ribose) polymerase 2 | -5.89567 |
| PMM2 | phosphomannomutase 2 | -5.76191 |
| UBE3C | ubiquitin protein ligase E3C | -5.24033 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -4.75592 |
| CYCS | cytochrome c, somatic | -4.62438 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.99191 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -3.50956 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.34443 |
| CAPN2 | calpain 2, (m/II) large subunit | -3.3297 |
| FKBP1C | FK506 binding protein 1C | -3.27492 |
| CDC25B | cell division cycle 25B | -3.19508 |
| ADD3 | adducin 3 (gamma) | -2.95965 |
| TMEM230 | transmembrane protein 230 | -2.8226 |
| PUDP | pseudouridine 5'-phosphatase | -2.78831 |
| ERGIC2 | ERGIC and golgi 2 | -2.73364 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.69477 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -2.65238 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.57387 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -2.51495 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -2.49857 |
| SMC1A | structural maintenance of chromosomes 1A | -2.43434 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -2.331 |
| DSG2 | desmoglein 2 | -2.29181 |
| KDM5C | lysine (K)-specific demethylase 5C | -2.27936 |
| PTGFR | prostaglandin F receptor (FP) | -2.23978 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.23543 |
| CBR3 | carbonyl reductase 3 | -2.23538 |
| DAD1 | defender against cell death 1 | -2.22438 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | -2.2198 |
| GPR88 | G protein-coupled receptor 88 | -2.13717 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B | -2.06369 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | -2.05677 |
| ZNF706 | zinc finger protein 706 | -2.04092 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -2.02539 |
