| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ficz 1.0 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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115 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.60351 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 4.60212 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 4.41169 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 3.70923 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 3.39459 |
| SPAG4 | sperm associated antigen 4 | 3.2826 |
| CDK19 | cyclin-dependent kinase 19 | 3.234 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.22533 |
| WDR7 | WD repeat domain 7 | 3.17294 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.07239 |
| MAMLD1 | mastermind-like domain containing 1 | 2.97884 |
| CCDC85B | coiled-coil domain containing 85B | 2.90556 |
| TGFB3 | transforming growth factor, beta 3 | 2.88038 |
| MCOLN1 | mucolipin 1 | 2.85977 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 2.64174 |
| SLC6A12 | solute carrier family 6 (neurotransmitter transporter), member 12 | 2.58719 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.55196 |
| TGM3 | transglutaminase 3 | 2.49329 |
| RAI14 | retinoic acid induced 14 | 2.48689 |
| TBX19 | T-box 19 | 2.4805 |
| MSRA | methionine sulfoxide reductase A | 2.43988 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.38374 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 2.37363 |
| EVPL | envoplakin | 2.35618 |
| NOX4 | NADPH oxidase 4 | 2.35467 |
| EDN1 | endothelin 1 | 2.35025 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 2.33052 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.31899 |
| DUSP2 | dual specificity phosphatase 2 | 2.30443 |
| HMG20B | high mobility group 20B | 2.28853 |
| DOC2A | double C2-like domains, alpha | 2.2503 |
| CMTR1 | cap methyltransferase 1 | 2.22428 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 | 2.19376 |
| ZNF750 | zinc finger protein 750 | 2.17182 |
| CORO1A | coronin, actin binding protein, 1A | 2.14033 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 | 2.1349 |
| VAV1 | vav 1 guanine nucleotide exchange factor | 2.13183 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 2.13154 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 2.12641 |
| SLC38A10 | solute carrier family 38, member 10 | 2.11475 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | 2.111 |
| STRADA | STE20-related kinase adaptor alpha | 2.10976 |
| TEX11 | testis expressed 11 | 2.10875 |
| SRD5A3 | steroid 5 alpha-reductase 3 | 2.10195 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 2.09609 |
| BHMT | betaine--homocysteine S-methyltransferase | 2.09339 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.081 |
| LOC124907012 | endogenous retrovirus group K member 7 Env polyprotein-like | 2.08054 |
| IL36A | interleukin 36, alpha | 2.06443 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 2.05034 |
| IL1RN | interleukin 1 receptor antagonist | 2.0322 |
| CD19 | CD19 molecule | 2.01723 |
| LGSN | lengsin, lens protein with glutamine synthetase domain | 2.01216 |
| PGAM4 | phosphoglycerate mutase family member 4 | 2.01046 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | 2.00835 |
| TMEM140 | transmembrane protein 140 | 2.0071 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 2.00471 |
| GH1 | growth hormone 1 | 2.00068 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -5.1293 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -4.41804 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.33106 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.16045 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -4.06109 |
| CCNB1 | cyclin B1 | -3.76337 |
| CBR3 | carbonyl reductase 3 | -3.6328 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -3.57372 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -3.38526 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -3.28141 |
| DSG2 | desmoglein 2 | -3.03649 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -3.0219 |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | -3.00546 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -2.97045 |
| RPN1 | ribophorin I | -2.85343 |
| THAP11 | THAP domain containing 11 | -2.78807 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -2.70974 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.66589 |
| NBPF19 | neuroblastoma breakpoint family, member 19 | -2.61373 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.5686 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | -2.53926 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -2.5306 |
| TATDN2 | TatD DNase domain containing 2 | -2.52087 |
| AZIN1 | antizyme inhibitor 1 | -2.4892 |
| RCOR3 | REST corepressor 3 | -2.48918 |
| TFDP1 | transcription factor Dp-1 | -2.46859 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -2.42571 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.41806 |
| KIF2C | kinesin family member 2C | -2.39839 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -2.38512 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -2.32082 |
| TP53 | tumor protein p53 | -2.30827 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | -2.27423 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.26683 |
| SLC35F2 | solute carrier family 35, member F2 | -2.23798 |
| LDHD | lactate dehydrogenase D | -2.23229 |
| NUP93 | nucleoporin 93kDa | -2.22098 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | -2.21546 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -2.21319 |
| S100A11 | S100 calcium binding protein A11 | -2.20546 |
| PCNP | PEST proteolytic signal containing nuclear protein | -2.17955 |
| ADI1 | acireductone dioxygenase 1 | -2.17832 |
| MPZL1 | myelin protein zero-like 1 | -2.16371 |
| GFUS | GDP-L-fucose synthase | -2.15676 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 | -2.15459 |
| MSMO1 | methylsterol monooxygenase 1 | -2.15451 |
| SLC25A46 | solute carrier family 25, member 46 | -2.13541 |
| BAG3 | BCL2-associated athanogene 3 | -2.12743 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | -2.11377 |
| CRYZ | crystallin, zeta (quinone reductase) | -2.10178 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -2.07596 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | -2.0636 |
| SMAP1 | small ArfGAP 1 | -2.05936 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.03951 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.0294 |
| MRPL18 | mitochondrial ribosomal protein L18 | -2.02386 |
| NCK2 | NCK adaptor protein 2 | -2.00165 |
