| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ficz 0.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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130 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 | 4.37359 |
| HYOU1 | hypoxia up-regulated 1 | 3.39241 |
| HDGFL3 | HDGF like 3 | 3.17496 |
| NSMCE4A | non-SMC element 4 homolog A (S. cerevisiae) | 3.05668 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 2.92121 |
| LAP3 | leucine aminopeptidase 3 | 2.79046 |
| STK38 | serine/threonine kinase 38 | 2.77379 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.64737 |
| TMEM35B | transmembrane protein 35B | 2.59231 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 2.57892 |
| MARCHF2 | membrane associated ring-CH-type finger 2 | 2.54381 |
| AOC3 | amine oxidase, copper containing 3 | 2.4701 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.46194 |
| TOR1B | torsin family 1, member B (torsin B) | 2.45099 |
| CREB3L4 | cAMP responsive element binding protein 3-like 4 | 2.43984 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N | 2.43501 |
| TRIP4 | thyroid hormone receptor interactor 4 | 2.41459 |
| ADPGK | ADP-dependent glucokinase | 2.40695 |
| CTAG2 | cancer/testis antigen 2 | 2.40488 |
| CADM1 | cell adhesion molecule 1 | 2.39738 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.37916 |
| TPO | thyroid peroxidase | 2.30507 |
| PPOX | protoporphyrinogen oxidase | 2.2982 |
| NIT1 | nitrilase 1 | 2.29099 |
| STBD1 | starch binding domain 1 | 2.28465 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.281 |
| INTS11 | integrator complex subunit 11 | 2.27352 |
| DNTT | DNA nucleotidylexotransferase | 2.25443 |
| ITGA7 | integrin, alpha 7 | 2.25222 |
| TESK1 | testis-specific kinase 1 | 2.22738 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 2.22694 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 2.22567 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | 2.22129 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 2.21744 |
| CYBC1 | cytochrome b-245 chaperone 1 | 2.21148 |
| LEP | leptin | 2.20705 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 2.20006 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.17696 |
| PLIN1 | perilipin 1 | 2.17083 |
| PDLIM3 | PDZ and LIM domain 3 | 2.14959 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 2.13939 |
| CBR4 | carbonyl reductase 4 | 2.13496 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 2.12171 |
| MAGEA4 | melanoma antigen family A4 | 2.12102 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 | 2.10452 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) | 2.10172 |
| VPREB1 | pre-B lymphocyte 1 | 2.09868 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C | 2.09415 |
| MCAM | melanoma cell adhesion molecule | 2.09227 |
| GMPR | guanosine monophosphate reductase | 2.09214 |
| CHKB | choline kinase beta | 2.08163 |
| ACP3 | acid phosphatase 3 | 2.0778 |
| PEX14 | peroxisomal biogenesis factor 14 | 2.07758 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 2.06865 |
| CHMP5 | charged multivesicular body protein 5 | 2.06559 |
| CFH | complement factor H | 2.06417 |
| POLI | polymerase (DNA directed) iota | 2.0494 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | 2.04384 |
| PCDHB11 | protocadherin beta 11 | 2.03754 |
| CDK5RAP1 | CDK5 regulatory subunit associated protein 1 | 2.03714 |
| FAM117A | family with sequence similarity 117, member A | 2.02048 |
| LAS1L | LAS1-like (S. cerevisiae) | 2.01832 |
| PRPSAP1 | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 2.01733 |
| QRICH1 | glutamine-rich 1 | 2.01445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -9.34373 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.50289 |
| ACTR10 | actin-related protein 10 homolog (S. cerevisiae) | -3.25995 |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit | -3.20384 |
| RWDD1 | RWD domain containing 1 | -3.06776 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | -3.05774 |
| RTRAF | RNA transcription, translation and transport factor | -3.00735 |
| CLTB | clathrin, light chain B | -2.99191 |
| RNF167 | ring finger protein 167 | -2.80827 |
| BATF | basic leucine zipper transcription factor, ATF-like | -2.72158 |
| CDC20 | cell division cycle 20 | -2.71011 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -2.64209 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.61734 |
| EIF1B | eukaryotic translation initiation factor 1B | -2.54209 |
| BAD | BCL2-associated agonist of cell death | -2.52703 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -2.49491 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | -2.46769 |
| KIAA0586 | KIAA0586 | -2.44333 |
| MSMO1 | methylsterol monooxygenase 1 | -2.42674 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | -2.40175 |
| ALS2CL | ALS2 C-terminal like | -2.40008 |
| PTOV1 | prostate tumor overexpressed 1 | -2.39084 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -2.38377 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -2.38196 |
| GABARAP | GABA(A) receptor-associated protein | -2.36333 |
| CKAP5 | cytoskeleton associated protein 5 | -2.34678 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 | -2.3433 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -2.3422 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -2.33759 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -2.33633 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -2.29752 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -2.29278 |
| RPS5 | ribosomal protein S5 | -2.29109 |
| HEATR1 | HEAT repeat containing 1 | -2.29104 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -2.28904 |
| RPL36AL | ribosomal protein L36a-like | -2.25143 |
| PSMG2 | proteasome (prosome, macropain) assembly chaperone 2 | -2.2464 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.24189 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -2.21278 |
| RHOG | ras homolog family member G | -2.20274 |
| JTB | jumping translocation breakpoint | -2.18559 |
| TFCP2L1 | transcription factor CP2-like 1 | -2.15927 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | -2.1479 |
| HOXB9 | homeobox B9 | -2.14093 |
| AFG3L2 | AFG3-like AAA ATPase 2 | -2.1389 |
| RPL36 | ribosomal protein L36 | -2.13676 |
| TP53 | tumor protein p53 | -2.1344 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.12906 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -2.10716 |
| LYRM4 | LYR motif containing 4 | -2.10158 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | -2.10147 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | -2.10019 |
| CTSD | cathepsin D | -2.08407 |
| THOC7 | THO complex 7 | -2.08256 |
| CD40LG | CD40 ligand | -2.07735 |
| KCTD11 | potassium channel tetramerization domain containing 11 | -2.07484 |
| CCDC6 | coiled-coil domain containing 6 | -2.0642 |
| CD82 | CD82 molecule | -2.06047 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -2.05954 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | -2.05134 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -2.01689 |
| MRPL48 | mitochondrial ribosomal protein L48 | -2.01658 |
| MST1R | macrophage stimulating 1 receptor | -2.01525 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | -2.01365 |
| DEXI | Dexi homolog (mouse) | -2.00855 |
| RAB1B | RAB1B, member RAS oncogene family | -2.00723 |
