CRCGN016_MCF10A.TP53.M_24H:B19 Gene Set
Genes
51 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
5.45594
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
2.49955
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.49059
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.40909
|
|
USP7
|
ubiquitin specific peptidase 7 (herpes virus-associated)
|
2.33297
|
|
TERT
|
telomerase reverse transcriptase
|
2.30551
|
|
UBE2L6
|
ubiquitin-conjugating enzyme E2L 6
|
2.2943
|
|
NUCB2
|
nucleobindin 2
|
2.28537
|
|
ZNF646
|
zinc finger protein 646
|
2.18347
|
|
ITGB7
|
integrin, beta 7
|
2.1747
|
|
AQP7
|
aquaporin 7
|
2.1642
|
|
TMEM212
|
transmembrane protein 212
|
2.15713
|
|
ADIPOQ
|
adiponectin, C1Q and collagen domain containing
|
2.15045
|
|
CLEC2D
|
C-type lectin domain family 2, member D
|
2.14842
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.1434
|
|
POLH
|
polymerase (DNA directed), eta
|
2.12965
|
|
DHX16
|
DEAH (Asp-Glu-Ala-His) box polypeptide 16
|
2.11725
|
|
LEP
|
leptin
|
2.107
|
|
FABP2
|
fatty acid binding protein 2, intestinal
|
2.10156
|
|
PVRIG
|
poliovirus receptor related immunoglobulin domain containing
|
2.08209
|
|
TMEM120B
|
transmembrane protein 120B
|
2.06677
|
|
PRR7
|
proline rich 7 (synaptic)
|
2.05522
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
2.01207
|
|
ADGRD2
|
adhesion G protein-coupled receptor D2
|
2.00997
|
|
HOXA5
|
homeobox A5
|
2.00592
|
|
ATF7IP2
|
activating transcription factor 7 interacting protein 2
|
2.0052
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MSMO1
|
methylsterol monooxygenase 1
|
-7.26983
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.48106
|
|
DSG2
|
desmoglein 2
|
-4.37577
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.86211
|
|
CCNB1
|
cyclin B1
|
-3.49357
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.22854
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-3.21148
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.19993
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-3.01996
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
-2.99638
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.97536
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
-2.95577
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.58866
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.47524
|
|
STMN1
|
stathmin 1
|
-2.30208
|
|
VTA1
|
vesicle (multivesicular body) trafficking 1
|
-2.24133
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.24064
|
|
ASCC3
|
activating signal cointegrator 1 complex subunit 3
|
-2.20485
|
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
-2.13664
|
|
RPS6KC1
|
ribosomal protein S6 kinase, 52kDa, polypeptide 1
|
-2.09899
|
|
IGFBP7
|
insulin-like growth factor binding protein 7
|
-2.08753
|
|
SNX6
|
sorting nexin 6
|
-2.07996
|
|
SSNA1
|
Sjogren syndrome nuclear autoantigen 1
|
-2.05956
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.02072
|
|
RPS5
|
ribosomal protein S5
|
-2.011
|
