CRCGN016_MCF10A.TP53.M_24H:B20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-methoxy-3-aminodibenzofuran 33.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.45263
TIAM1 T-cell lymphoma invasion and metastasis 1 2.83428
FSD1 fibronectin type III and SPRY domain containing 1 2.53015
NUTF2 nuclear transport factor 2 2.1136

decreased expression

Symbol Name Standardized Value
MAPK13 mitogen-activated protein kinase 13 -5.5051
CAB39 calcium binding protein 39 -5.2069
RPIA ribose 5-phosphate isomerase A -4.81645
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.3902
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.525
NGRN neugrin, neurite outgrowth associated -2.4042
ST14 suppression of tumorigenicity 14 (colon carcinoma) -2.01935
LINC02762 long intergenic non-protein coding RNA 2762 -2.01325