CRCGN016_MCF10A.TP53.M_24H:C02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description pcb126 3.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

51 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:C02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KDM5D lysine (K)-specific demethylase 5D 5.46841
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 5.26862
HBA1 hemoglobin, alpha 1 4.97911
HBB hemoglobin, beta 4.59082
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 4.57307
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 4.30822
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.84346
GATA3 GATA binding protein 3 3.83094
ADRB2 adrenoceptor beta 2, surface 3.41914
USP9Y ubiquitin specific peptidase 9, Y-linked 3.1743
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 3.05587
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 2.72038
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.62447
LMO2 LIM domain only 2 (rhombotin-like 1) 2.62189
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.48612
NLGN4Y neuroligin 4, Y-linked 2.4055
CUX2 cut-like homeobox 2 2.33747
RTP4 receptor (chemosensory) transporter protein 4 2.30593
ZFY zinc finger protein, Y-linked 2.30402
CEP15 centrosomal protein 15 2.22499
RPS4Y1 ribosomal protein S4, Y-linked 1 2.21244
GIMAP6 GTPase, IMAP family member 6 2.15062
METTL4 methyltransferase like 4 2.14405
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 2.09737
MUC1 mucin 1, cell surface associated 2.08858
CARTPT CART prepropeptide 2.04221
ZCCHC10 zinc finger, CCHC domain containing 10 2.03208
ART3 ADP-ribosyltransferase 3 2.01128
ARID4B AT rich interactive domain 4B (RBP1-like) 2.00112

decreased expression

Symbol Name Standardized Value
COTL1 coactosin-like F-actin binding protein 1 -5.50615
SMC1A structural maintenance of chromosomes 1A -5.32719
DIPK1A divergent protein kinase domain 1A -5.16658
HMG20B high mobility group 20B -4.40338
KDM5C lysine (K)-specific demethylase 5C -4.28308
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -4.03741
PIH1D1 PIH1 domain containing 1 -3.66245
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -3.63077
USP9X ubiquitin specific peptidase 9, X-linked -3.62541
NT5DC2 5'-nucleotidase domain containing 2 -3.44572
UBA1 ubiquitin-like modifier activating enzyme 1 -3.23469
TUBA4A tubulin, alpha 4a -2.91891
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.89578
THAP11 THAP domain containing 11 -2.8809
PUDP pseudouridine 5'-phosphatase -2.68136
OFD1 oral-facial-digital syndrome 1 -2.63264
KDM6A lysine (K)-specific demethylase 6A -2.52985
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.40435
IKZF5 IKAROS family zinc finger 5 (Pegasus) -2.22909
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -2.1895
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.1388
PNPLA4 patatin-like phospholipase domain containing 4 -2.12943