CRCGN016_MCF10A.TP53.M_24H:C03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description pcb126 1.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:C03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
IGHMBP2 immunoglobulin mu binding protein 2 3.09328
HYOU1 hypoxia up-regulated 1 2.79134
UBQLN2 ubiquilin 2 2.72134
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.5555
VGLL4 vestigial-like family member 4 2.43683
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.2073
TBPL1 TBP-like 1 2.14294

decreased expression

Symbol Name Standardized Value
C2CD5 C2 calcium-dependent domain containing 5 -4.93934
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.14739
CORO1A coronin, actin binding protein, 1A -2.38856
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.37128
ANXA2 annexin A2 -2.29507
MBNL2 muscleblind-like splicing regulator 2 -2.11201
STK25 serine/threonine kinase 25 -2.02143