CRCGN016_MCF10A.TP53.M_24H:C06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description indirubin 11.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:C06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KLHL21 kelch-like family member 21 6.13572
CCP110 centriolar coiled coil protein 110kDa 4.40627
HLA-DRA major histocompatibility complex, class II, DR alpha 3.68857
PECR peroxisomal trans-2-enoyl-CoA reductase 3.00762
TBPL1 TBP-like 1 2.77047
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.66067
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.59399
CCDC85B coiled-coil domain containing 85B 2.50055
HMOX1 heme oxygenase 1 2.42513
VPS35L VPS35 endosomal protein sorting factor like 2.25477
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.22042
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.20159

decreased expression

Symbol Name Standardized Value
ACOT9 acyl-CoA thioesterase 9 -4.32255
KRT14 keratin 14, type I -3.66312
ANXA2 annexin A2 -3.56415
MLEC malectin -2.44447
CDK6 cyclin-dependent kinase 6 -2.2487
OXA1L oxidase (cytochrome c) assembly 1-like -2.24515
REXO2 RNA exonuclease 2 -2.22685
PADI3 peptidyl arginine deiminase, type III -2.0781
KDM3A lysine (K)-specific demethylase 3A -2.0644
COTL1 coactosin-like F-actin binding protein 1 -2.02673
MTERF3 mitochondrial transcription termination factor 3 -2.00175