CRCGN016_MCF10A.TP53.M_24H:C09 Gene Set
Genes
32 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TXNRD1
|
thioredoxin reductase 1
|
4.44627
|
|
AARS1
|
alanyl-tRNA synthetase 1
|
3.61853
|
|
TLR4
|
toll-like receptor 4
|
3.54223
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
3.51667
|
|
MICALL1
|
MICAL-like 1
|
3.34664
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
3.24972
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.09011
|
|
HMOX1
|
heme oxygenase 1
|
3.05731
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.90563
|
|
TBX2
|
T-box 2
|
2.79111
|
|
TCEA2
|
transcription elongation factor A (SII), 2
|
2.75776
|
|
FHL2
|
four and a half LIM domains 2
|
2.74275
|
|
MTHFD2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
2.59787
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
2.42154
|
|
EIF4EBP1
|
eukaryotic translation initiation factor 4E binding protein 1
|
2.1713
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-4.35079
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
-3.66315
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
-3.34628
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.27531
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
-3.26794
|
|
S100A4
|
S100 calcium binding protein A4
|
-3.05396
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-3.05279
|
|
PRR15L
|
proline rich 15-like
|
-3.03217
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
-2.94808
|
|
KRT14
|
keratin 14, type I
|
-2.76922
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.71773
|
|
GADD45B
|
growth arrest and DNA-damage-inducible, beta
|
-2.70449
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.45983
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-2.43954
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.3219
|
|
CAPN1
|
calpain 1, (mu/I) large subunit
|
-2.16676
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
-2.13128
|
