CRCGN016_MCF10A.TP53.M_24H:C11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description pcb126 with tbt perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:C11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.3389
TLR4 toll-like receptor 4 4.03854
TCEA2 transcription elongation factor A (SII), 2 3.18014
TBPL1 TBP-like 1 2.6514
DENND2D DENN/MADD domain containing 2D 2.56049
TPD52L2 tumor protein D52-like 2 2.49369
CCDC85B coiled-coil domain containing 85B 2.48867
GPATCH8 G patch domain containing 8 2.27418
HDGFL3 HDGF like 3 2.24527
COA3 cytochrome c oxidase assembly factor 3 2.10197
GPN1 GPN-loop GTPase 1 2.0502

decreased expression

Symbol Name Standardized Value
RPIA ribose 5-phosphate isomerase A -4.8556
TNIP1 TNFAIP3 interacting protein 1 -4.55784
SCYL3 SCY1-like 3 (S. cerevisiae) -4.46767
ANKRD10 ankyrin repeat domain 10 -3.42048
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.99895
MALT1 MALT1 paracaspase -2.96262
MGLL monoglyceride lipase -2.39518
SPRY4 sprouty homolog 4 (Drosophila) -2.37876
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.02689
COTL1 coactosin-like F-actin binding protein 1 -2.0234