CRCGN016_MCF10A.TP53.M_24H:C12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description pcb126 with tbt perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:C12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.29388
ADAM10 ADAM metallopeptidase domain 10 2.54271
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.44058
CHEK1 checkpoint kinase 1 2.41907
HYOU1 hypoxia up-regulated 1 2.261

decreased expression

Symbol Name Standardized Value
FASTKD5 FAST kinase domains 5 -3.70876
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.43462
NT5DC2 5'-nucleotidase domain containing 2 -3.31184
KRT14 keratin 14, type I -3.07767
KDM3A lysine (K)-specific demethylase 3A -2.67171
REEP5 receptor accessory protein 5 -2.20009
IFRD2 interferon-related developmental regulator 2 -2.17708
RALGDS ral guanine nucleotide dissociation stimulator -2.12693
TXNRD1 thioredoxin reductase 1 -2.04844