CRCGN016_MCF10A.TP53.M_24H:C13 Gene Set
Genes
31 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:C13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
3.9904
|
|
MEF2C
|
myocyte enhancer factor 2C
|
3.08472
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.69937
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.58155
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.56641
|
|
CFAP298
|
cilia and flagella associated protein 298
|
2.4724
|
|
HMOX1
|
heme oxygenase 1
|
2.41761
|
|
COMP
|
cartilage oligomeric matrix protein
|
2.27102
|
|
ATG16L1
|
autophagy related 16-like 1 (S. cerevisiae)
|
2.24287
|
|
WDR76
|
WD repeat domain 76
|
2.17588
|
|
NOTCH1
|
notch 1
|
2.16217
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.06282
|
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
2.04939
|
|
WIF1
|
WNT inhibitory factor 1
|
2.0225
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-4.31059
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-3.6475
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-3.63341
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.28636
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-3.26144
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-3.21557
|
|
COG2
|
component of oligomeric golgi complex 2
|
-2.9695
|
|
HMG20B
|
high mobility group 20B
|
-2.91522
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.88568
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.87292
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.83812
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.70125
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-2.46362
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-2.44293
|
|
SLC7A7
|
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
|
-2.26754
|
|
PRR15L
|
proline rich 15-like
|
-2.22828
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.07524
|
