CRCGN016_MCF10A.TP53.M_24H:C16 Gene Set
Genes
46 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:C16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
4.62784
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.55754
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
4.52698
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.85819
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
3.37012
|
|
WIF1
|
WNT inhibitory factor 1
|
3.18934
|
|
CCNH
|
cyclin H
|
2.65564
|
|
PPOX
|
protoporphyrinogen oxidase
|
2.4779
|
|
COQ8A
|
coenzyme Q8A
|
2.4434
|
|
COMP
|
cartilage oligomeric matrix protein
|
2.37133
|
|
SLC37A4
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4
|
2.36107
|
|
ATF5
|
activating transcription factor 5
|
2.30137
|
|
MOK
|
MOK protein kinase
|
2.22265
|
|
POLL
|
polymerase (DNA directed), lambda
|
2.16818
|
|
CYP2W1
|
cytochrome P450, family 2, subfamily W, polypeptide 1
|
2.09457
|
|
RUVBL1
|
RuvB-like AAA ATPase 1
|
2.06986
|
|
KRI1
|
KRI1 homolog (S. cerevisiae)
|
2.02901
|
|
RRP9
|
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
|
2.02696
|
|
MAP1S
|
microtubule-associated protein 1S
|
2.02325
|
|
DVL1
|
dishevelled segment polarity protein 1
|
2.0153
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.00231
|
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
2.00196
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-5.50062
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-5.44279
|
|
TCTA
|
T-cell leukemia translocation altered
|
-5.37767
|
|
CCNB1
|
cyclin B1
|
-3.67215
|
|
KIF14
|
kinesin family member 14
|
-3.47236
|
|
KIF20A
|
kinesin family member 20A
|
-3.37244
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.32958
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-3.2005
|
|
LYPLA1
|
lysophospholipase I
|
-3.05073
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-2.7384
|
|
BPNT2
|
3'(2'), 5'-bisphosphate nucleotidase 2
|
-2.66012
|
|
ZMYM2
|
zinc finger, MYM-type 2
|
-2.52681
|
|
THEM6
|
thioesterase superfamily member 6
|
-2.48889
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.41811
|
|
FNDC3B
|
fibronectin type III domain containing 3B
|
-2.40286
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.3644
|
|
EIF1AY
|
eukaryotic translation initiation factor 1A, Y-linked
|
-2.32082
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.25332
|
|
IQGAP1
|
IQ motif containing GTPase activating protein 1
|
-2.20557
|
|
KDM5D
|
lysine (K)-specific demethylase 5D
|
-2.18512
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.1523
|
|
PIGZ
|
phosphatidylinositol glycan anchor biosynthesis, class Z
|
-2.10945
|
|
SOSTDC1
|
sclerostin domain containing 1
|
-2.06177
|
|
USP9Y
|
ubiquitin specific peptidase 9, Y-linked
|
-2.03452
|