CRCGN016_MCF10A.TP53.M_24H:C24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vorinostat 1.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

1444 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:C24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 8.75948
PRCP prolylcarboxypeptidase (angiotensinase C) 7.67613
PRAF2 PRA1 domain family, member 2 7.391
VAT1 vesicle amine transport 1 7.22353
S100A4 S100 calcium binding protein A4 6.95283
GAA glucosidase, alpha; acid 6.87918
STXBP1 syntaxin binding protein 1 6.87242
TMEM50A transmembrane protein 50A 6.78668
WFS1 Wolfram syndrome 1 (wolframin) 6.45392
UBE2L6 ubiquitin-conjugating enzyme E2L 6 6.43616
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 6.1281
ALDOC aldolase C, fructose-bisphosphate 5.99822
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 5.89218
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 5.76787
NIT1 nitrilase 1 5.72351
SYNGR3 synaptogyrin 3 5.52524
FYN FYN proto-oncogene, Src family tyrosine kinase 5.48343
NUCB2 nucleobindin 2 5.35861
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 5.21156
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 5.21109
NIPSNAP1 nipsnap homolog 1 (C. elegans) 5.15063
AGR2 anterior gradient 2 5.04847
CEMIP2 cell migration inducing hyaluronidase 2 4.98578
NME7 NME/NM23 family member 7 4.9388
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 4.90949
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 4.87437
PLA2G15 phospholipase A2, group XV 4.74012
PTPN1 protein tyrosine phosphatase, non-receptor type 1 4.71169
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 4.65465
GABARAPL2 GABA(A) receptor-associated protein-like 2 4.64194
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 4.63048
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 4.62821
ZNF586 zinc finger protein 586 4.59515
CADM1 cell adhesion molecule 1 4.59447
GLRX glutaredoxin (thioltransferase) 4.57695
CNRIP1 cannabinoid receptor interacting protein 1 4.49282
EPN2 epsin 2 4.47478
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 4.46626
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 4.44572
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.43197
DHRS2 dehydrogenase/reductase (SDR family) member 2 4.35671
CREG1 cellular repressor of E1A-stimulated genes 1 4.34174
FGFR4 fibroblast growth factor receptor 4 4.34166
FOXO4 forkhead box O4 4.2729
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.26184
SFXN3 sideroflexin 3 4.24187
MINDY1 MINDY lysine 48 deubiquitinase 1 4.22465
MOSPD3 motile sperm domain containing 3 4.21079
TRAK2 trafficking protein, kinesin binding 2 4.20921
SNAP25 synaptosomal-associated protein, 25kDa 4.17671
CHIC2 cysteine-rich hydrophobic domain 2 4.13649
DHRS7 dehydrogenase/reductase (SDR family) member 7 4.1017
SGCE sarcoglycan, epsilon 4.0899
HDAC5 histone deacetylase 5 4.08884
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 4.06924
DYNLT3 dynein, light chain, Tctex-type 3 4.06625
RTN3 reticulon 3 4.05794
DHRS1 dehydrogenase/reductase (SDR family) member 1 4.04964
SKIC2 SKI2 subunit of superkiller complex 4.03867
SERTAD3 SERTA domain containing 3 4.03737
CDPF1 cysteine-rich, DPF motif domain containing 1 4.03413
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 4.0243
PEG10 paternally expressed 10 4.00971
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 4.00254
DUSP4 dual specificity phosphatase 4 3.98535
IFT52 intraflagellar transport 52 3.98512
FHL2 four and a half LIM domains 2 3.98039
MAN2B1 mannosidase, alpha, class 2B, member 1 3.96129
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 3.90347
TBCB tubulin folding cofactor B 3.88403
WBP1L WW domain binding protein 1-like 3.88018
RRAS related RAS viral (r-ras) oncogene homolog 3.86437
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 3.84355
OXSR1 oxidative stress responsive 1 3.83068
CCL20 chemokine (C-C motif) ligand 20 3.82509
TMEM59 transmembrane protein 59 3.82392
NDRG3 NDRG family member 3 3.82322
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 3.74626
DUSP14 dual specificity phosphatase 14 3.70298
BLVRA biliverdin reductase A 3.66493
TXNRD1 thioredoxin reductase 1 3.65462
KIF3C kinesin family member 3C 3.65034
RAB31 RAB31, member RAS oncogene family 3.63429
HS1BP3 HCLS1 binding protein 3 3.6227
METRN meteorin, glial cell differentiation regulator 3.62107
FAM114A1 family with sequence similarity 114, member A1 3.61347
ANO10 anoctamin 10 3.59427
CALCOCO1 calcium binding and coiled-coil domain 1 3.58355
KIF3B kinesin family member 3B 3.56409
RBKS ribokinase 3.55345
PCYOX1L prenylcysteine oxidase 1 like 3.55167
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 3.54654
RAB8B RAB8B, member RAS oncogene family 3.54524
TMEM184B transmembrane protein 184B 3.51685
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 3.51432
GRN granulin 3.49628
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 3.49042
CLDND1 claudin domain containing 1 3.48985
COL21A1 collagen, type XXI, alpha 1 3.48669
ABHD6 abhydrolase domain containing 6 3.47457
GSTA4 glutathione S-transferase alpha 4 3.47138
ZNHIT1 zinc finger, HIT-type containing 1 3.45234
MBD5 methyl-CpG binding domain protein 5 3.42903
PRSS23 protease, serine, 23 3.40703
DOCK1 dedicator of cytokinesis 1 3.40495
SPAG16 sperm associated antigen 16 3.39724
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 3.38809
TCTN1 tectonic family member 1 3.38238
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.37403
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 3.36885
IGF2R insulin-like growth factor 2 receptor 3.36853
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 3.36233
OCEL1 occludin/ELL domain containing 1 3.34686
SMIM29 small integral membrane protein 29 3.34311
CCDC85B coiled-coil domain containing 85B 3.3372
FGD1 FYVE, RhoGEF and PH domain containing 1 3.31999
WASHC5 WASH complex subunit 5 3.31168
KIAA0930 KIAA0930 3.30541
GDI1 GDP dissociation inhibitor 1 3.29532
FIG4 FIG4 phosphoinositide 5-phosphatase 3.28936
RABAC1 Rab acceptor 1 (prenylated) 3.28569
NECAB3 N-terminal EF-hand calcium binding protein 3 3.28099
PLA1A phospholipase A1 member A 3.27987
RTL8C retrotransposon Gag like 8C 3.2797
MMD monocyte to macrophage differentiation-associated 3.27687
BCL10 B-cell CLL/lymphoma 10 3.27114
TM4SF20 transmembrane 4 L six family member 20 3.26699
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 3.2654
ZMAT5 zinc finger, matrin-type 5 3.23161
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 3.22752
GPC3 glypican 3 3.22724
IFI6 interferon, alpha-inducible protein 6 3.22152
SDC3 syndecan 3 3.22089
ZC4H2 zinc finger, C4H2 domain containing 3.21987
MAPK3 mitogen-activated protein kinase 3 3.21334
TBPL1 TBP-like 1 3.21107
DKK3 dickkopf WNT signaling pathway inhibitor 3 3.19593
INTS3 integrator complex subunit 3 3.19524
ELOB elongin B 3.18705
TUBB2B tubulin, beta 2B class IIb 3.18674
PIEZO2 piezo-type mechanosensitive ion channel component 2 3.18221
CBR1 carbonyl reductase 1 3.1713
SSBP2 single-stranded DNA binding protein 2 3.16846
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 3.1609
CDK19 cyclin-dependent kinase 19 3.15921
RAB5B RAB5B, member RAS oncogene family 3.15066
FAT1 FAT atypical cadherin 1 3.14192
SARAF store-operated calcium entry-associated regulatory factor 3.13483
TUBB4A tubulin, beta 4A class IVa 3.1233
CCDC6 coiled-coil domain containing 6 3.10888
NISCH nischarin 3.10835
AGTPBP1 ATP/GTP binding protein 1 3.10662
CRYZ crystallin, zeta (quinone reductase) 3.10508
CLTC clathrin, heavy chain (Hc) 3.09358
BOLA2B bolA family member 2B 3.0931
SATB1 SATB homeobox 1 3.08105
ELOVL4 ELOVL fatty acid elongase 4 3.07706
SLC67A1 solute carrier family 67 member 1 3.06391
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 3.05813
HEBP1 heme binding protein 1 3.05305
PPP4C protein phosphatase 4, catalytic subunit 3.0459
EPHB2 EPH receptor B2 3.04471
CHMP2A charged multivesicular body protein 2A 3.04155
CHMP1B charged multivesicular body protein 1B 3.03078
WIF1 WNT inhibitory factor 1 3.02712
DUSP10 dual specificity phosphatase 10 3.02394
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 3.02007
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 3.01737
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 3.01729
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 3.00933
EIF3L eukaryotic translation initiation factor 3, subunit L 3.00698
TWF2 twinfilin actin binding protein 2 3.00344
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 2.99689
TTLL1 tubulin tyrosine ligase-like family member 1 2.98618
STX8 syntaxin 8 2.9564
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 2.95077
ARID5B AT rich interactive domain 5B (MRF1-like) 2.95063
MYH9 myosin, heavy chain 9, non-muscle 2.94426
LCMT1 leucine carboxyl methyltransferase 1 2.94026
GM2A GM2 ganglioside activator 2.93979
KIFAP3 kinesin-associated protein 3 2.93314
RAP1GAP RAP1 GTPase activating protein 2.92616
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.92069
MMP24OS MMP24 opposite strand 2.92045
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 2.91729
HMG20B high mobility group 20B 2.91551
BACE2 beta-site APP-cleaving enzyme 2 2.91473
SIPA1 signal-induced proliferation-associated 1 2.91117
JARID2 jumonji, AT rich interactive domain 2 2.90973
WDR47 WD repeat domain 47 2.90348
ANXA5 annexin A5 2.90057
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.89608
ABLIM3 actin binding LIM protein family, member 3 2.89182
TCIM transcriptional and immune response regulator 2.88677
NXPE3 neurexophilin and PC-esterase domain family, member 3 2.87858
PM20D1 peptidase M20 domain containing 1 2.8781
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.87467
FAXDC2 fatty acid hydroxylase domain containing 2 2.87222
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.85961
MARK4 MAP/microtubule affinity-regulating kinase 4 2.85297
PRSS3 protease, serine, 3 2.85105
TMEM134 transmembrane protein 134 2.84849
TM7SF2 transmembrane 7 superfamily member 2 2.8417
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 2.83988
ADGRE5 adhesion G protein-coupled receptor E5 2.83861
DLL3 delta-like 3 (Drosophila) 2.83861
COPS8 COP9 signalosome subunit 8 2.82998
KCTD5 potassium channel tetramerization domain containing 5 2.82815
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.82194
FAM131A family with sequence similarity 131, member A 2.82186
STX5 syntaxin 5 2.82159
TSG101 tumor susceptibility 101 2.81567
EVI5 ecotropic viral integration site 5 2.81018
ARL3 ADP-ribosylation factor-like 3 2.80955
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 2.80932
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.80786
TPPP3 tubulin polymerization-promoting protein family member 3 2.80345
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 2.79909
CALCOCO2 calcium binding and coiled-coil domain 2 2.7965
NECAP2 NECAP endocytosis associated 2 2.79483
RAP2A RAP2A, member of RAS oncogene family 2.79384
NPY1R neuropeptide Y receptor Y1 2.79206
RNF11 ring finger protein 11 2.78867
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.78804
TRIB1 tribbles pseudokinase 1 2.78555
HAL histidine ammonia-lyase 2.78443
EFNB2 ephrin-B2 2.78436
ELL2 elongation factor, RNA polymerase II, 2 2.77998
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.7793
BBLN bublin coiled coil protein 2.77659
MAPK7 mitogen-activated protein kinase 7 2.77331
MUC13 mucin 13, cell surface associated 2.77146
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.76462
PSENEN presenilin enhancer gamma secretase subunit 2.76108
DDR1 discoidin domain receptor tyrosine kinase 1 2.76075
EGR3 early growth response 3 2.75797
GNPAT glyceronephosphate O-acyltransferase 2.75412
WHRN whirlin 2.75336
FIBP fibroblast growth factor (acidic) intracellular binding protein 2.74933
BCORL1 BCL6 corepressor-like 1 2.74403
AGBL5 ATP/GTP binding protein-like 5 2.74328
DSTN destrin (actin depolymerizing factor) 2.7426
BABAM2 BRISC and BRCA1 A complex member 2 2.74151
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 2.73846
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.73269
F3 coagulation factor III (thromboplastin, tissue factor) 2.72643
WDTC1 WD and tetratricopeptide repeats 1 2.72303
WDR26 WD repeat domain 26 2.71995
CD3D CD3d molecule, delta (CD3-TCR complex) 2.71461
IST1 increased sodium tolerance 1 homolog (yeast) 2.71442
RNF103 ring finger protein 103 2.70652
PROS1 protein S (alpha) 2.70526
LEPROTL1 leptin receptor overlapping transcript-like 1 2.70487
TIMP2 TIMP metallopeptidase inhibitor 2 2.70222
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.70102
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 2.69652
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.69232
CYB5R3 cytochrome b5 reductase 3 2.68676
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 2.68668
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 2.68574
LTA4H leukotriene A4 hydrolase 2.68521
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.6848
STUM stum, mechanosensory transduction mediator homolog 2.68203
AAMDC adipogenesis associated, Mth938 domain containing 2.67586
TMPRSS15 transmembrane protease, serine 15 2.67562
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.67523
UFM1 ubiquitin-fold modifier 1 2.67263
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 2.67146
KIAA0040 KIAA0040 2.66791
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.66265
MAP1B microtubule-associated protein 1B 2.66148
PORCN porcupine homolog (Drosophila) 2.66037
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 2.65959
STN1 STN1 subunit of CST complex 2.65807
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.65426
TOR1AIP2 torsin A interacting protein 2 2.65194
APLP1 amyloid beta (A4) precursor-like protein 1 2.65151
OLFML2A olfactomedin-like 2A 2.6465
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 2.64448
COG2 component of oligomeric golgi complex 2 2.64366
IGF1R insulin-like growth factor 1 receptor 2.64348
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 2.63985
ATOX1 antioxidant 1 copper chaperone 2.63704
IRS1 insulin receptor substrate 1 2.63704
ITGAV integrin, alpha V 2.63653
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 2.63235
AVPI1 arginine vasopressin-induced 1 2.6309
IL1B interleukin 1, beta 2.62719
PKNOX2 PBX/knotted 1 homeobox 2 2.62657
CDA cytidine deaminase 2.62505
CAMLG calcium modulating ligand 2.61966
JUND jun D proto-oncogene 2.61862
MFAP1 microfibrillar-associated protein 1 2.61814
ECI2 enoyl-CoA delta isomerase 2 2.61771
EYA1 EYA transcriptional coactivator and phosphatase 1 2.61085
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 2.61025
TMEM40 transmembrane protein 40 2.60868
IFNG interferon, gamma 2.60655
MLPH melanophilin 2.60611
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.60581
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.60434
LGALS1 lectin, galactoside-binding, soluble, 1 2.59971
EHD2 EH-domain containing 2 2.5972
AHNAK2 AHNAK nucleoprotein 2 2.59476
MFGE8 milk fat globule-EGF factor 8 protein 2.59236
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 2.59113
KIF3A kinesin family member 3A 2.58996
PDLIM1 PDZ and LIM domain 1 2.58893
RBBP9 retinoblastoma binding protein 9 2.58744
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 2.5853
PRSS2 protease, serine, 2 (trypsin 2) 2.58495
IGBP1 immunoglobulin (CD79A) binding protein 1 2.58383
CNN3 calponin 3, acidic 2.58308
MBNL2 muscleblind-like splicing regulator 2 2.58225
TRPC1 transient receptor potential cation channel, subfamily C, member 1 2.58138
ARHGAP29 Rho GTPase activating protein 29 2.58111
CDR2L cerebellar degeneration-related protein 2-like 2.57959
TSPAN31 tetraspanin 31 2.57379
MCOLN1 mucolipin 1 2.57198
PRDX1 peroxiredoxin 1 2.57037
MVP major vault protein 2.5671
ATOSB atos homolog B 2.56367
ASB13 ankyrin repeat and SOCS box containing 13 2.56338
TUBA4B tubulin, alpha 4b 2.56189
ANKZF1 ankyrin repeat and zinc finger domain containing 1 2.5553
PPARG peroxisome proliferator-activated receptor gamma 2.55465
NRIP1 nuclear receptor interacting protein 1 2.55442
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 2.55302
MNT MAX network transcriptional repressor 2.53994
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 2.53683
PMM1 phosphomannomutase 1 2.53317
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.52056
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 2.52047
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.51864
STX10 syntaxin 10 2.51454
TBC1D16 TBC1 domain family, member 16 2.51175
SPANXA1 sperm protein associated with the nucleus, X-linked, family member A1 2.50891
COG5 component of oligomeric golgi complex 5 2.50859
NKAIN1 Na+/K+ transporting ATPase interacting 1 2.508
CCNG2 cyclin G2 2.5053
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 2.50411
NOCT nocturnin 2.50302
L1CAM L1 cell adhesion molecule 2.49925
AMZ2 archaelysin family metallopeptidase 2 2.49619
GNS glucosamine (N-acetyl)-6-sulfatase 2.49211
RAB7A RAB7A, member RAS oncogene family 2.48909
EPB41L2 erythrocyte membrane protein band 4.1-like 2 2.48443
CUTA cutA divalent cation tolerance homolog (E. coli) 2.4824
CDK5 cyclin-dependent kinase 5 2.48118
CSRP1 cysteine and glycine-rich protein 1 2.48084
ZNF706 zinc finger protein 706 2.47846
VPS13B vacuolar protein sorting 13 homolog B (yeast) 2.47823
FNDC4 fibronectin type III domain containing 4 2.47759
SNX24 sorting nexin 24 2.47745
HOMER2 homer scaffolding protein 2 2.47627
TUBG2 tubulin, gamma 2 2.4758
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 2.47286
ADRB2 adrenoceptor beta 2, surface 2.47245
DUSP5 dual specificity phosphatase 5 2.47129
MEAF6 MYST/Esa1-associated factor 6 2.46877
ERCC1 excision repair cross-complementation group 1 2.46288
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.46144
PLD3 phospholipase D family, member 3 2.45987
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 2.45959
MTMR11 myotubularin related protein 11 2.45764
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 2.45759
GABARAP GABA(A) receptor-associated protein 2.45462
EXTL2 exostosin-like glycosyltransferase 2 2.45104
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 2.44576
ASMTL acetylserotonin O-methyltransferase-like 2.44425
PYCR1 pyrroline-5-carboxylate reductase 1 2.44246
AGFG1 ArfGAP with FG repeats 1 2.44054
GPSM3 G-protein signaling modulator 3 2.43785
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.43627
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 2.43512
CKB creatine kinase, brain 2.434
BTG1 B-cell translocation gene 1, anti-proliferative 2.43335
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 2.4305
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.42664
WASHC3 WASH complex subunit 3 2.42412
MGST3 microsomal glutathione S-transferase 3 2.42285
COPG1 coatomer protein complex, subunit gamma 1 2.41885
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 2.41644
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 2.41551
MAGED2 melanoma antigen family D2 2.41537
ELOVL5 ELOVL fatty acid elongase 5 2.40977
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.40508
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 2.40504
MXD4 MAX dimerization protein 4 2.40486
BTG2 BTG family, member 2 2.40435
CDHR1 cadherin-related family member 1 2.40142
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 2.40062
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 2.39319
NDRG4 NDRG family member 4 2.39213
BBS7 Bardet-Biedl syndrome 7 2.39126
TTLL7 tubulin tyrosine ligase-like family member 7 2.38874
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.38817
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.38608
PTGFR prostaglandin F receptor (FP) 2.38603
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.38448
SIK2 salt-inducible kinase 2 2.38403
ARFIP2 ADP-ribosylation factor interacting protein 2 2.38384
BLVRB biliverdin reductase B 2.37943
VKORC1 vitamin K epoxide reductase complex, subunit 1 2.37752
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 2.37742
DMBT1 deleted in malignant brain tumors 1 2.37585
PHKB phosphorylase kinase, beta 2.37158
LIG4 ligase IV, DNA, ATP-dependent 2.36617
PHF21A PHD finger protein 21A 2.36224
POPDC3 popeye domain containing 3 2.35618
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.35253
FBXL7 F-box and leucine-rich repeat protein 7 2.35113
JUN jun proto-oncogene 2.35089
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 2.34873
ZNF277 zinc finger protein 277 2.3475
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.34017
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 2.33774
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.33713
CGGBP1 CGG triplet repeat binding protein 1 2.33663
INSIG2 insulin induced gene 2 2.33527
RAP1A RAP1A, member of RAS oncogene family 2.3307
EXT2 exostosin glycosyltransferase 2 2.32898
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 2.32838
TSPAN15 tetraspanin 15 2.32798
PSEN2 presenilin 2 2.32652
GULP1 GULP, engulfment adaptor PTB domain containing 1 2.32649
VASH1 vasohibin 1 2.3257
CCDC186 coiled-coil domain containing 186 2.3249
GLO1 glyoxalase I 2.32099
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.3183
STAT1 signal transducer and activator of transcription 1, 91kDa 2.31713
EFNB1 ephrin-B1 2.31645
AHCYL1 adenosylhomocysteinase-like 1 2.31483
YPEL5 yippee-like 5 (Drosophila) 2.3137
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 2.3129
IFT81 intraflagellar transport 81 2.31268
CLDN18 claudin 18 2.3106
P3H1 prolyl 3-hydroxylase 1 2.30938
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 2.30936
MYH10 myosin, heavy chain 10, non-muscle 2.30858
RB1CC1 RB1-inducible coiled-coil 1 2.30736
DCTN1 dynactin 1 2.30668
SALL2 spalt-like transcription factor 2 2.30608
SIN3B SIN3 transcription regulator family member B 2.30513
SERF2 small EDRK-rich factor 2 2.30484
SERINC3 serine incorporator 3 2.30238
PRR14 proline rich 14 2.30229
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 2.30178
RHOB ras homolog family member B 2.30028
ATP7A ATPase, Cu++ transporting, alpha polypeptide 2.29775
DNAL4 dynein, axonemal, light chain 4 2.29748
MOSPD2 motile sperm domain containing 2 2.29743
NACAD NAC alpha domain containing 2.29529
TMEM45A transmembrane protein 45A 2.29478
SIAH1 siah E3 ubiquitin protein ligase 1 2.29014
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 2.28996
NECTIN3 nectin cell adhesion molecule 3 2.28902
UBXN7 UBX domain protein 7 2.28864
USP33 ubiquitin specific peptidase 33 2.28587
KDM5B lysine (K)-specific demethylase 5B 2.28586
RHOC ras homolog family member C 2.2832
CALCA calcitonin-related polypeptide alpha 2.27942
TOX3 TOX high mobility group box family member 3 2.27777
APH1B APH1B gamma secretase subunit 2.27685
EID1 EP300 interacting inhibitor of differentiation 1 2.27613
GTF2B general transcription factor IIB 2.27572
FLRT2 fibronectin leucine rich transmembrane protein 2 2.27454
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.27394
DCTN3 dynactin 3 (p22) 2.27183
DGAT1 diacylglycerol O-acyltransferase 1 2.26686
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 2.26623
SECISBP2L SECIS binding protein 2-like 2.26574
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.26499
TMED7 transmembrane emp24 protein transport domain containing 7 2.26333
RAB26 RAB26, member RAS oncogene family 2.26319
PCDH12 protocadherin 12 2.26267
EXOC2 exocyst complex component 2 2.26262
CLDN5 claudin 5 2.26124
GNG12 guanine nucleotide binding protein (G protein), gamma 12 2.25929
MUL1 mitochondrial E3 ubiquitin protein ligase 1 2.25876
FKBP9 FK506 binding protein 9, 63 kDa 2.25868
CSNK1G3 casein kinase 1, gamma 3 2.25604
GLB1L galactosidase, beta 1-like 2.25456
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.25363
IL6ST interleukin 6 signal transducer 2.25327
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 2.25122
NR4A3 nuclear receptor subfamily 4, group A, member 3 2.24528
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.24464
ACBD4 acyl-CoA binding domain containing 4 2.24463
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 2.24421
EFHC1 EF-hand domain (C-terminal) containing 1 2.24364
IL36RN interleukin 36 receptor antagonist 2.24306
ZNF587 zinc finger protein 587 2.24061
BAD BCL2-associated agonist of cell death 2.23495
ARRB2 arrestin, beta 2 2.23462
RAB38 RAB38, member RAS oncogene family 2.23423
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.23346
GSTA3 glutathione S-transferase alpha 3 2.23233
BMPR1B bone morphogenetic protein receptor, type IB 2.23035
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 2.22972
GUK1 guanylate kinase 1 2.22783
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 2.22754
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 2.22706
DOK7 docking protein 7 2.22704
TUFT1 tuftelin 1 2.22445
STX2 syntaxin 2 2.22184
BCAS4 breast carcinoma amplified sequence 4 2.22095
REPS2 RALBP1 associated Eps domain containing 2 2.22067
BBS1 Bardet-Biedl syndrome 1 2.21998
GOLGB1 golgin B1 2.21926
CCL21 chemokine (C-C motif) ligand 21 2.21836
PLEKHO2 pleckstrin homology domain containing, family O member 2 2.21672
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 2.21618
NRCAM neuronal cell adhesion molecule 2.21039
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.21005
FGG fibrinogen gamma chain 2.2098
RBP1 retinol binding protein 1, cellular 2.20897
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 2.20638
NQO2 NAD(P)H dehydrogenase, quinone 2 2.20638
NDFIP1 Nedd4 family interacting protein 1 2.2048
CORO1A coronin, actin binding protein, 1A 2.19988
CBX4 chromobox homolog 4 2.19406
NPY5R neuropeptide Y receptor Y5 2.18868
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 2.18579
SNX6 sorting nexin 6 2.18356
NDRG1 N-myc downstream regulated 1 2.18008
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 2.17958
CTSF cathepsin F 2.17878
UEVLD UEV and lactate/malate dehyrogenase domains 2.17738
TSPAN13 tetraspanin 13 2.17689
LDLRAD4 low density lipoprotein receptor class A domain containing 4 2.17676
WASF3 WAS protein family, member 3 2.17577
SNF8 SNF8, ESCRT-II complex subunit 2.17485
KLHL9 kelch-like family member 9 2.17419
TXNIP thioredoxin interacting protein 2.17413
TES testin LIM domain protein 2.17319
ZNF606 zinc finger protein 606 2.17259
TMEM132A transmembrane protein 132A 2.17018
GRK5 G protein-coupled receptor kinase 5 2.16981
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 2.16858
GYG2 glycogenin 2 2.16844
NBPF19 neuroblastoma breakpoint family, member 19 2.16801
GNA13 guanine nucleotide binding protein (G protein), alpha 13 2.16754
FAM107A family with sequence similarity 107, member A 2.16554
CTSA cathepsin A 2.16519
GNG11 guanine nucleotide binding protein (G protein), gamma 11 2.16511
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.16471
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 2.16466
TRIM2 tripartite motif containing 2 2.16304
LGMN legumain 2.16299
PELO pelota homolog (Drosophila) 2.16255
NELFE negative elongation factor complex member E 2.16098
TTC17 tetratricopeptide repeat domain 17 2.1609
CA14 carbonic anhydrase XIV 2.15475
KANSL1 KAT8 regulatory NSL complex subunit 1 2.15421
TRIM23 tripartite motif containing 23 2.15189
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.15051
RNMT RNA (guanine-7-) methyltransferase 2.15013
GPR137B G protein-coupled receptor 137B 2.14944
TBC1D19 TBC1 domain family, member 19 2.14767
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.14687
ZBED2 zinc finger, BED-type containing 2 2.14605
DUSP6 dual specificity phosphatase 6 2.14551
FCMR Fc fragment of IgM receptor 2.14473
TMEM164 transmembrane protein 164 2.14347
UBE2H ubiquitin-conjugating enzyme E2H 2.14285
FPGT fucose-1-phosphate guanylyltransferase 2.14192
HDAC2 histone deacetylase 2 2.1418
STX1A syntaxin 1A (brain) 2.13954
IFT20 intraflagellar transport 20 2.13911
LORICRIN loricrin cornified envelope precursor protein 2.1371
PROCR protein C receptor, endothelial 2.13586
STMN2 stathmin 2 2.13545
SENP7 SUMO1/sentrin specific peptidase 7 2.13502
TAC4 tachykinin 4 (hemokinin) 2.13039
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 2.12995
CSF1R colony stimulating factor 1 receptor 2.12925
SNRPN small nuclear ribonucleoprotein polypeptide N 2.12888
RNF167 ring finger protein 167 2.12688
ITPKC inositol-trisphosphate 3-kinase C 2.12443
LRP10 low density lipoprotein receptor-related protein 10 2.12114
ENO2 enolase 2 (gamma, neuronal) 2.11695
SNTA1 syntrophin, alpha 1 2.11693
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 2.11641
MAG myelin associated glycoprotein 2.11617
NECTIN2 nectin cell adhesion molecule 2 2.11579
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 2.115
VEGFC vascular endothelial growth factor C 2.11485
SUCO SUN domain containing ossification factor 2.11477
RASL11B RAS-like, family 11, member B 2.11338
TRIM16 tripartite motif containing 16 2.11299
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 2.11154
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.11098
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 2.10994
COMMD9 COMM domain containing 9 2.10746
WSB1 WD repeat and SOCS box containing 1 2.10743
BBOF1 basal body orientation factor 1 2.1045
RALB v-ral simian leukemia viral oncogene homolog B 2.10364
HSF2BP heat shock transcription factor 2 binding protein 2.10349
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 2.1006
IDS iduronate 2-sulfatase 2.09956
NME3 NME/NM23 nucleoside diphosphate kinase 3 2.09439
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 2.0937
VAMP3 vesicle-associated membrane protein 3 2.08863
SUMO1 small ubiquitin-like modifier 1 2.08852
ADRA2A adrenoceptor alpha 2A 2.0871
CALU calumenin 2.08709
ADGRG2 adhesion G protein-coupled receptor G2 2.08378
MFSD1 major facilitator superfamily domain containing 1 2.08237
IER3 immediate early response 3 2.07974
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 2.07951
SHARPIN SHANK-associated RH domain interactor 2.07759
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 2.07598
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 2.07472
EDIL3 EGF-like repeats and discoidin I-like domains 3 2.07307
FLRT3 fibronectin leucine rich transmembrane protein 3 2.0692
JAG1 jagged 1 2.0674
DYNLRB1 dynein, light chain, roadblock-type 1 2.06723
CETN2 centrin, EF-hand protein, 2 2.06717
PFN2 profilin 2 2.06538
TMCC2 transmembrane and coiled-coil domain family 2 2.06535
SLC39A6 solute carrier family 39 (zinc transporter), member 6 2.06518
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 2.06495
STX12 syntaxin 12 2.06341
CIDEC cell death-inducing DFFA-like effector c 2.06268
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 2.06257
SLC38A6 solute carrier family 38, member 6 2.06236
IL22RA1 interleukin 22 receptor, alpha 1 2.06174
NFS1 NFS1 cysteine desulfurase 2.06137
LRRC42 leucine rich repeat containing 42 2.05905
MAP3K12 mitogen-activated protein kinase kinase kinase 12 2.05656
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 2.05572
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 2.05279
DNM3 dynamin 3 2.05274
TYW2 tRNA wybutosine-synthesizing protein 2 2.05028
KDM6B lysine (K)-specific demethylase 6B 2.04993
LYST lysosomal trafficking regulator 2.04915
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 2.04842
MACROH2A1 macroH2A.1 histone 2.04769
CHD4 chromodomain helicase DNA binding protein 4 2.04547
TPGS2 tubulin polyglutamylase complex subunit 2 2.0449
KRT1 keratin 1, type II 2.04173
SYT12 synaptotagmin XII 2.04156
MXRA7 matrix-remodelling associated 7 2.04035
UBL5 ubiquitin-like 5 2.03864
UBE2W ubiquitin-conjugating enzyme E2W (putative) 2.03841
COPA coatomer protein complex, subunit alpha 2.03813
LRRC49 leucine rich repeat containing 49 2.03698
SF3B5 splicing factor 3b, subunit 5, 10kDa 2.03613
IRS2 insulin receptor substrate 2 2.03611
PRKCZ protein kinase C, zeta 2.03376
FANCF Fanconi anemia, complementation group F 2.03367
PALLD palladin, cytoskeletal associated protein 2.03295
C1QL1 complement component 1, q subcomponent-like 1 2.03209
AGER advanced glycosylation end product-specific receptor 2.03171
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.03117
DOK2 docking protein 2, 56kDa 2.03109
UBXN1 UBX domain protein 1 2.02732
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.02352
TSPAN5 tetraspanin 5 2.02317
PEX19 peroxisomal biogenesis factor 19 2.02217
LDOC1 leucine zipper, down-regulated in cancer 1 2.02127
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 2.01989
SCAND1 SCAN domain containing 1 2.01957
ZMYM5 zinc finger, MYM-type 5 2.0171
IER5 immediate early response 5 2.01551
TNNT1 troponin T type 1 (skeletal, slow) 2.01354
HDAC3 histone deacetylase 3 2.01292
RNF139 ring finger protein 139 2.01251
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.01165
PID1 phosphotyrosine interaction domain containing 1 2.01013
SPANXB1 SPANX family, member B1 2.00776
SEZ6L2 seizure related 6 homolog (mouse)-like 2 2.00773
PHF20L1 PHD finger protein 20-like 1 2.00707
SNAI2 snail family zinc finger 2 2.0066
PRKCD protein kinase C, delta 2.00573
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 2.0045
RAB6B RAB6B, member RAS oncogene family 2.00319
SCARB1 scavenger receptor class B, member 1 2.00147
INTS8 integrator complex subunit 8 2.00053
TOB2 transducer of ERBB2, 2 2.00049

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -10.0
ATF5 activating transcription factor 5 -9.49654
CDC45 cell division cycle 45 -9.1639
KIF20A kinesin family member 20A -8.44446
CCNB2 cyclin B2 -8.37225
PCNA proliferating cell nuclear antigen -8.33745
PLK1 polo-like kinase 1 -8.00886
MSRA methionine sulfoxide reductase A -7.80723
UBE2C ubiquitin-conjugating enzyme E2C -7.603
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -7.36282
DCK deoxycytidine kinase -7.18734
SPAG7 sperm associated antigen 7 -7.09625
KIF14 kinesin family member 14 -6.97692
KEAP1 kelch-like ECH-associated protein 1 -6.91384
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -6.78627
FOXM1 forkhead box M1 -6.75677
AURKB aurora kinase B -6.73155
NCAPH non-SMC condensin I complex, subunit H -6.36715
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -6.29046
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -6.24465
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -6.20862
CD320 CD320 molecule -6.13942
CCNA2 cyclin A2 -5.98603
KIF15 kinesin family member 15 -5.98092
CDCA8 cell division cycle associated 8 -5.91088
TOP2A topoisomerase (DNA) II alpha 170kDa -5.87531
KIF11 kinesin family member 11 -5.87352
NUP85 nucleoporin 85kDa -5.86771
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -5.85567
FANCI Fanconi anemia, complementation group I -5.71265
TTK TTK protein kinase -5.67767
KIF4A kinesin family member 4A -5.66983
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -5.66137
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -5.56802
CDC25A cell division cycle 25A -5.54237
ASCC3 activating signal cointegrator 1 complex subunit 3 -5.50941
TROAP trophinin associated protein -5.46493
CDT1 chromatin licensing and DNA replication factor 1 -5.4489
GINS3 GINS complex subunit 3 (Psf3 homolog) -5.44745
C1QBP complement component 1, q subcomponent binding protein -5.42534
CHEK1 checkpoint kinase 1 -5.39987
NCAPG2 non-SMC condensin II complex, subunit G2 -5.3733
KIF23 kinesin family member 23 -5.31792
TUBB6 tubulin, beta 6 class V -5.31697
MCM5 minichromosome maintenance complex component 5 -5.30228
FXN frataxin -5.30005
BIRC5 baculoviral IAP repeat containing 5 -5.29655
NEIL3 nei endonuclease VIII-like 3 (E. coli) -5.29506
BID BH3 interacting domain death agonist -5.24773
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -5.23087
MCM10 minichromosome maintenance complex component 10 -5.23036
SPAG5 sperm associated antigen 5 -5.22601
BRCA1 breast cancer 1, early onset -5.14003
DNA2 DNA replication helicase/nuclease 2 -5.09987
FASN fatty acid synthase -5.04609
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -5.01782
KIF18A kinesin family member 18A -4.9905
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.9811
ASF1B anti-silencing function 1B histone chaperone -4.95711
HJURP Holliday junction recognition protein -4.94349
DERA deoxyribose-phosphate aldolase (putative) -4.90386
POLE polymerase (DNA directed), epsilon, catalytic subunit -4.90063
CDC20 cell division cycle 20 -4.87524
TK1 thymidine kinase 1, soluble -4.85651
MCM3 minichromosome maintenance complex component 3 -4.85479
SPC25 SPC25, NDC80 kinetochore complex component -4.79788
ERCC6L excision repair cross-complementation group 6-like -4.78512
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -4.76688
CEP55 centrosomal protein 55kDa -4.7527
KIF18B kinesin family member 18B -4.74934
PRC1 protein regulator of cytokinesis 1 -4.72151
HMMR hyaluronan-mediated motility receptor (RHAMM) -4.72072
LMNB1 lamin B1 -4.71822
SHCBP1 SHC SH2-domain binding protein 1 -4.71542
EXO1 exonuclease 1 -4.70382
SLC35F2 solute carrier family 35, member F2 -4.61569
CDK1 cyclin-dependent kinase 1 -4.60178
ERAP2 endoplasmic reticulum aminopeptidase 2 -4.58727
SYNE2 spectrin repeat containing, nuclear envelope 2 -4.57734
PARPBP PARP1 binding protein -4.5767
CDC6 cell division cycle 6 -4.53848
AURKA aurora kinase A -4.51208
RAD51AP1 RAD51 associated protein 1 -4.49534
PARP2 poly (ADP-ribose) polymerase 2 -4.44209
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.4367
ST20-MTHFS ST20-MTHFS readthrough -4.41484
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -4.39316
USP1 ubiquitin specific peptidase 1 -4.38856
CHAF1B chromatin assembly factor 1, subunit B (p60) -4.38663
MCM7 minichromosome maintenance complex component 7 -4.38441
TCERG1 transcription elongation regulator 1 -4.38417
CIAPIN1 cytokine induced apoptosis inhibitor 1 -4.37267
NDC80 NDC80 kinetochore complex component -4.37145
STMN1 stathmin 1 -4.35539
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -4.32521
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -4.32038
PBK PDZ binding kinase -4.31314
OXA1L oxidase (cytochrome c) assembly 1-like -4.30857
ACOD1 aconitate decarboxylase 1 -4.28736
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -4.25784
YEATS4 YEATS domain containing 4 -4.23195
DEPDC1 DEP domain containing 1 -4.21998
BCL7B B-cell CLL/lymphoma 7B -4.20375
CCT8 chaperonin containing TCP1, subunit 8 (theta) -4.20339
TIMELESS timeless circadian clock -4.20201
MAK16 MAK16 homolog (S. cerevisiae) -4.19698
NUSAP1 nucleolar and spindle associated protein 1 -4.19028
DONSON downstream neighbor of SON -4.18001
FEN1 flap structure-specific endonuclease 1 -4.15224
CCNB1 cyclin B1 -4.13261
DBF4 DBF4 zinc finger -4.10764
NEK2 NIMA-related kinase 2 -4.09985
KRT14 keratin 14, type I -4.06364
C2CD5 C2 calcium-dependent domain containing 5 -4.05425
BORA bora, aurora kinase A activator -4.0512
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -4.04151
PFAS phosphoribosylformylglycinamidine synthase -4.03487
RXYLT1 ribitol xylosyltransferase 1 -4.02971
TACC3 transforming, acidic coiled-coil containing protein 3 -4.0064
FIRRM FIGNL1 interacting regulator of recombination and mitosis -4.00087
WDHD1 WD repeat and HMG-box DNA binding protein 1 -3.99225
SKA1 spindle and kinetochore associated complex subunit 1 -3.99208
CDCA3 cell division cycle associated 3 -3.98214
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.97442
AUNIP aurora kinase A and ninein interacting protein -3.9595
TIPIN TIMELESS interacting protein -3.94804
HMGB2 high mobility group box 2 -3.94748
ANKRD10 ankyrin repeat domain 10 -3.93551
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -3.92792
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -3.92754
PCNT pericentrin -3.90898
MCM9 minichromosome maintenance complex component 9 -3.90352
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.90015
MCM4 minichromosome maintenance complex component 4 -3.893
RCC1 regulator of chromosome condensation 1 -3.88551
TMEM39B transmembrane protein 39B -3.87821
CENPA centromere protein A -3.86985
CENPN centromere protein N -3.84116
TMPO thymopoietin -3.83372
TRIP13 thyroid hormone receptor interactor 13 -3.83223
POLK polymerase (DNA directed) kappa -3.832
OIP5 Opa interacting protein 5 -3.82742
CHAF1A chromatin assembly factor 1, subunit A (p150) -3.82526
BAZ1A bromodomain adjacent to zinc finger domain, 1A -3.81553
MKI67 marker of proliferation Ki-67 -3.80023
SMNDC1 survival motor neuron domain containing 1 -3.77706
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -3.76343
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.75433
DKC1 dyskeratosis congenita 1, dyskerin -3.74618
GTPBP6 GTP binding protein 6 (putative) -3.73365
RFC2 replication factor C (activator 1) 2, 40kDa -3.73041
KIFC1 kinesin family member C1 -3.72539
TCOF1 Treacher Collins-Franceschetti syndrome 1 -3.72001
CDK4 cyclin-dependent kinase 4 -3.71847
CCNF cyclin F -3.69391
ARHGAP11A Rho GTPase activating protein 11A -3.66731
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -3.66635
MSH2 mutS homolog 2 -3.61944
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.61516
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -3.60406
E2F8 E2F transcription factor 8 -3.59672
POLR1G RNA polymerase I subunit G -3.59255
MDN1 MDN1, midasin homolog (yeast) -3.58532
RYR1 ryanodine receptor 1 (skeletal) -3.58193
PRPF8 pre-mRNA processing factor 8 -3.57734
RAD51 RAD51 recombinase -3.5721
CENPI centromere protein I -3.5661
PUS1 pseudouridylate synthase 1 -3.5621
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.55888
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.55442
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -3.55348
RFC3 replication factor C (activator 1) 3, 38kDa -3.55228
NAT10 N-acetyltransferase 10 (GCN5-related) -3.54934
CTSO cathepsin O -3.54713
CENPE centromere protein E, 312kDa -3.54318
RPIA ribose 5-phosphate isomerase A -3.52184
ZWINT ZW10 interacting kinetochore protein -3.51538
H2AX H2A.X variant histone -3.51401
AGMAT agmatine ureohydrolase (agmatinase) -3.50998
FANCC Fanconi anemia, complementation group C -3.50261
MELK maternal embryonic leucine zipper kinase -3.50194
VRK1 vaccinia related kinase 1 -3.48171
F8A2 coagulation factor VIII-associated 2 -3.46832
MORC3 MORC family CW-type zinc finger 3 -3.46141
HNRNPM heterogeneous nuclear ribonucleoprotein M -3.4601
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -3.4568
DSN1 DSN1, MIS12 kinetochore complex component -3.45382
MYO19 myosin XIX -3.45316
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) -3.44204
NUBP2 nucleotide binding protein 2 -3.43795
RACGAP1 Rac GTPase activating protein 1 -3.43666
NEMP1 nuclear envelope integral membrane protein 1 -3.41623
FBXO5 F-box protein 5 -3.40879
PLK4 polo-like kinase 4 -3.40528
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 -3.38407
DHFR dihydrofolate reductase -3.3802
S100A8 S100 calcium binding protein A8 -3.3727
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -3.36949
KRT5 keratin 5, type II -3.35488
EIF5 eukaryotic translation initiation factor 5 -3.35078
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -3.35047
GTSE1 G-2 and S-phase expressed 1 -3.33802
PILRB paired immunoglobin-like type 2 receptor beta -3.31544
THUMPD2 THUMP domain containing 2 -3.31045
FZD7 frizzled class receptor 7 -3.30831
TP53 tumor protein p53 -3.30826
BAG3 BCL2-associated athanogene 3 -3.30806
DCTD dCMP deaminase -3.30755
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -3.30618
AVEN apoptosis, caspase activation inhibitor -3.3024
TEAD4 TEA domain family member 4 -3.29835
EXOSC8 exosome component 8 -3.28889
IPO4 importin 4 -3.2802
ACOT2 acyl-CoA thioesterase 2 -3.27594
GMPPB GDP-mannose pyrophosphorylase B -3.27507
THOP1 thimet oligopeptidase 1 -3.27257
SPRY2 sprouty homolog 2 (Drosophila) -3.27023
ZC3H4 zinc finger CCCH-type containing 4 -3.26847
ARMC6 armadillo repeat containing 6 -3.26625
VBP1 von Hippel-Lindau binding protein 1 -3.26588
KNTC1 kinetochore associated 1 -3.25802
KANSL2 KAT8 regulatory NSL complex subunit 2 -3.25188
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -3.24402
DNM1L dynamin 1-like -3.24401
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -3.24346
LBR lamin B receptor -3.23914
AEN apoptosis enhancing nuclease -3.2341
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.2291
CASP8AP2 caspase 8 associated protein 2 -3.21681
HAUS7 HAUS augmin-like complex, subunit 7 -3.2032
ANAPC10 anaphase promoting complex subunit 10 -3.19778
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -3.19257
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.18856
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -3.18238
RAD54L RAD54-like (S. cerevisiae) -3.17483
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -3.17377
POMK protein-O-mannose kinase -3.16797
CENPC centromere protein C -3.16034
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.15956
MCUR1 mitochondrial calcium uniporter regulator 1 -3.15475
GRWD1 glutamate-rich WD repeat containing 1 -3.15463
NOL8 nucleolar protein 8 -3.15123
SRSF4 serine/arginine-rich splicing factor 4 -3.14962
LRRC41 leucine rich repeat containing 41 -3.1446
CUTC cutC copper transporter -3.14243
MRPS2 mitochondrial ribosomal protein S2 -3.14168
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -3.13488
RCC1L RCC1 like -3.13305
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -3.11793
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -3.1116
NMI N-myc (and STAT) interactor -3.10292
TOE1 target of EGR1, member 1 (nuclear) -3.10206
TFDP1 transcription factor Dp-1 -3.10111
SPOUT1 SPOUT domain containing methyltransferase 1 -3.1006
SFMBT1 Scm-like with four mbt domains 1 -3.09931
CTCF CCCTC-binding factor (zinc finger protein) -3.09775
IFRD2 interferon-related developmental regulator 2 -3.09502
PCCB propionyl CoA carboxylase, beta polypeptide -3.09405
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -3.08619
CLUH clustered mitochondria (cluA/CLU1) homolog -3.08411
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -3.08064
CTPS1 CTP synthase 1 -3.07907
NUP54 nucleoporin 54kDa -3.07538
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) -3.07434
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -3.06526
TTC31 tetratricopeptide repeat domain 31 -3.06219
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -3.06194
USP21 ubiquitin specific peptidase 21 -3.06048
NUP210 nucleoporin 210kDa -3.06004
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -3.05946
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -3.05359
ECT2 epithelial cell transforming 2 -3.05122
REPIN1 replication initiator 1 -3.04545
LTF lactotransferrin -3.03855
USP18 ubiquitin specific peptidase 18 -3.03729
ECH1 enoyl CoA hydratase 1, peroxisomal -3.03578
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -3.03471
DPP3 dipeptidyl-peptidase 3 -3.03011
TRAIP TRAF interacting protein -3.02866
GEMIN4 gem (nuclear organelle) associated protein 4 -3.02801
MPZL2 myelin protein zero-like 2 -3.0185
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -3.01661
RBL1 retinoblastoma-like 1 -3.01206
MCMBP minichromosome maintenance complex binding protein -3.01042
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -3.00963
PRPF3 pre-mRNA processing factor 3 -3.00354
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.99522
WRAP73 WD repeat containing, antisense to TP73 -2.99197
COQ6 coenzyme Q6 monooxygenase -2.98854
VCPKMT valosin containing protein lysine (K) methyltransferase -2.98235
PIMREG PICALM interacting mitotic regulator -2.98035
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.97852
FAM149A family with sequence similarity 149, member A -2.9704
PREB prolactin regulatory element binding -2.96988
RRM2 ribonucleotide reductase M2 -2.96956
E2F1 E2F transcription factor 1 -2.96583
CNTRL centriolin -2.9617
WDR6 WD repeat domain 6 -2.9503
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -2.94754
NSD2 nuclear receptor binding SET domain protein 2 -2.93633
TRIM22 tripartite motif containing 22 -2.93484
NUP107 nucleoporin 107kDa -2.92199
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.91689
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -2.91494
NOP16 NOP16 nucleolar protein -2.90663
YJU2 YJU2 splicing factor homolog -2.90595
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.90505
LUC7L2 LUC7-like 2 (S. cerevisiae) -2.9034
METTL1 methyltransferase like 1 -2.89938
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.89866
BHMT betaine--homocysteine S-methyltransferase -2.89849
DDB2 damage-specific DNA binding protein 2, 48kDa -2.89343
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -2.89278
SNRPA small nuclear ribonucleoprotein polypeptide A -2.89185
NCAPD3 non-SMC condensin II complex, subunit D3 -2.89153
MRPL15 mitochondrial ribosomal protein L15 -2.89032
MIS18A MIS18 kinetochore protein A -2.8893
CENPS-CORT CENPS-CORT readthrough -2.88814
MAPK13 mitogen-activated protein kinase 13 -2.88685
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -2.88362
HELLS helicase, lymphoid-specific -2.87522
CBR3 carbonyl reductase 3 -2.87121
GAR1 GAR1 ribonucleoprotein -2.86486
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.86342
SAE1 SUMO1 activating enzyme subunit 1 -2.85442
ENOSF1 enolase superfamily member 1 -2.85244
RBM23 RNA binding motif protein 23 -2.84125
LAMP5 lysosomal-associated membrane protein family, member 5 -2.84069
NUP205 nucleoporin 205kDa -2.83496
TUBGCP4 tubulin, gamma complex associated protein 4 -2.83332
MTX2 metaxin 2 -2.82206
SYK spleen tyrosine kinase -2.81593
PRPF4 pre-mRNA processing factor 4 -2.81501
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.80635
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -2.80349
IRAK1 interleukin-1 receptor-associated kinase 1 -2.80226
WDR43 WD repeat domain 43 -2.79959
NLRP4 NLR family, pyrin domain containing 4 -2.79951
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -2.7988
HSPA8 heat shock 70kDa protein 8 -2.79556
NOP14 NOP14 nucleolar protein -2.79261
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -2.79005
HMGN2 high mobility group nucleosomal binding domain 2 -2.78818
LAMP3 lysosomal-associated membrane protein 3 -2.78792
FPGS folylpolyglutamate synthase -2.78709
RAB33B RAB33B, member RAS oncogene family -2.78614
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.78586
HAT1 histone acetyltransferase 1 -2.78455
ELAC2 elaC ribonuclease Z 2 -2.78345
ARAF A-Raf proto-oncogene, serine/threonine kinase -2.78341
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -2.7813
BLM Bloom syndrome, RecQ helicase-like -2.77967
SMG9 SMG9 nonsense mediated mRNA decay factor -2.77803
STRN4 striatin, calmodulin binding protein 4 -2.77569
MCM6 minichromosome maintenance complex component 6 -2.77252
HROB homologous recombination factor with OB-fold -2.76949
CAPN15 calpain 15 -2.76401
TUBGCP3 tubulin, gamma complex associated protein 3 -2.76299
PRSS16 protease, serine, 16 (thymus) -2.7628
RFWD3 ring finger and WD repeat domain 3 -2.76241
CKS1B CDC28 protein kinase regulatory subunit 1B -2.76053
RBM14-RBM4 RBM14-RBM4 readthrough -2.75869
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.75822
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -2.75707
PHF2 PHD finger protein 2 -2.7528
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.75242
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.75145
SPDL1 spindle apparatus coiled-coil protein 1 -2.75112
PDF peptide deformylase (mitochondrial) -2.74526
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.74412
PUM3 pumilio RNA binding family member 3 -2.74396
GALP galanin-like peptide -2.74378
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.74089
MRPL46 mitochondrial ribosomal protein L46 -2.74018
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -2.74002
JADE2 jade family PHD finger 2 -2.73981
DSCC1 DNA replication and sister chromatid cohesion 1 -2.7382
RPN1 ribophorin I -2.73152
TRMT5 tRNA methyltransferase 5 -2.72417
MRPL39 mitochondrial ribosomal protein L39 -2.72392
KMT5A lysine methyltransferase 5A -2.71873
SETD6 SET domain containing 6 -2.71624
AK8 adenylate kinase 8 -2.71284
SMC4 structural maintenance of chromosomes 4 -2.70998
HMGB1 high mobility group box 1 -2.70421
ANAPC1 anaphase promoting complex subunit 1 -2.70114
TYMS thymidylate synthetase -2.69516
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -2.69458
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.69103
TOR3A torsin family 3, member A -2.69046
MOK MOK protein kinase -2.68462
MRM3 mitochondrial rRNA methyltransferase 3 -2.68252
EPCAM epithelial cell adhesion molecule -2.67993
CUL1 cullin 1 -2.67395
GYG1 glycogenin 1 -2.6736
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -2.67251
KIF22 kinesin family member 22 -2.6692
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.66486
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.6642
PGM1 phosphoglucomutase 1 -2.66044
TMED1 transmembrane emp24 protein transport domain containing 1 -2.65934
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -2.65929
GLOD4 glyoxalase domain containing 4 -2.65924
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.65786
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.65558
SMYD5 SMYD family member 5 -2.64942
ESRP2 epithelial splicing regulatory protein 2 -2.64725
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -2.6444
PUF60 poly-U binding splicing factor 60KDa -2.63984
INTS14 integrator complex subunit 14 -2.6326
AKAP1 A kinase (PRKA) anchor protein 1 -2.63167
PCLAF PCNA clamp associated factor -2.62772
NLE1 notchless homolog 1 (Drosophila) -2.6261
UBXN8 UBX domain protein 8 -2.62572
SNUPN snurportin 1 -2.62542
MYBBP1A MYB binding protein (P160) 1a -2.62246
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.62007
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -2.61923
CCDC59 coiled-coil domain containing 59 -2.61765
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -2.61731
INTS7 integrator complex subunit 7 -2.61504
SPRR3 small proline-rich protein 3 -2.61406
ENDOG endonuclease G -2.6087
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.60126
TEX30 testis expressed 30 -2.59779
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -2.59394
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.59276
FKBP11 FK506 binding protein 11, 19 kDa -2.58626
DAZAP1 DAZ associated protein 1 -2.57589
USP19 ubiquitin specific peptidase 19 -2.57287
CYB561D2 cytochrome b561 family, member D2 -2.56507
RAD54B RAD54 homolog B (S. cerevisiae) -2.56309
UNG uracil-DNA glycosylase -2.56125
WDR62 WD repeat domain 62 -2.56105
WWC2 WW and C2 domain containing 2 -2.56055
CENPM centromere protein M -2.55947
RIOX1 ribosomal oxygenase 1 -2.55862
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -2.55832
AK6 adenylate kinase 6 -2.55713
PSRC1 proline/serine-rich coiled-coil 1 -2.55471
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -2.54703
CCDC15 coiled-coil domain containing 15 -2.54555
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -2.53918
CDC7 cell division cycle 7 -2.53897
ZNF107 zinc finger protein 107 -2.53684
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -2.53022
PMF1-BGLAP PMF1-BGLAP readthrough -2.52996
DUSP2 dual specificity phosphatase 2 -2.52732
TEDC2 tubulin epsilon and delta complex 2 -2.52726
VRK2 vaccinia related kinase 2 -2.5224
HYI hydroxypyruvate isomerase (putative) -2.51901
RMI1 RecQ mediated genome instability 1 -2.51453
TIMCC TIM double twin CX3C motif chaperone -2.51073
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -2.5106
SSBP1 single-stranded DNA binding protein 1, mitochondrial -2.5066
TLK2 tousled-like kinase 2 -2.50438
ZWILCH zwilch kinetochore protein -2.50247
CDKN2AIP CDKN2A interacting protein -2.50194
THEM6 thioesterase superfamily member 6 -2.49766
EXPH5 exophilin 5 -2.49313
LARP7 La ribonucleoprotein domain family, member 7 -2.49111
PEX26 peroxisomal biogenesis factor 26 -2.48845
ST14 suppression of tumorigenicity 14 (colon carcinoma) -2.487
SRPRA SRP receptor subunit alpha -2.48611
PALB2 partner and localizer of BRCA2 -2.48505
FANCA Fanconi anemia, complementation group A -2.48069
NUP155 nucleoporin 155kDa -2.47583
SH2D4A SH2 domain containing 4A -2.47337
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.45908
CDC25C cell division cycle 25C -2.45673
URGCP upregulator of cell proliferation -2.45384
LYRM2 LYR motif containing 2 -2.4535
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 -2.4503
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -2.45028
RBM19 RNA binding motif protein 19 -2.44917
TGFB3 transforming growth factor, beta 3 -2.44708
PTCD3 pentatricopeptide repeat domain 3 -2.44573
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -2.44549
CHEK2 checkpoint kinase 2 -2.44489
ARMCX5 armadillo repeat containing, X-linked 5 -2.44366
SMAGP small cell adhesion glycoprotein -2.44162
MLH3 mutL homolog 3 -2.43185
PYGM phosphorylase, glycogen, muscle -2.42764
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) -2.42561
TPGS1 tubulin polyglutamylase complex subunit 1 -2.42258
CLDN1 claudin 1 -2.42023
PCBP1 poly(rC) binding protein 1 -2.41747
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.41602
DACT1 dishevelled-binding antagonist of beta-catenin 1 -2.41248
LAGE3 L antigen family, member 3 -2.41101
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -2.40885
NUP62 nucleoporin 62kDa -2.40869
CFAP298 cilia and flagella associated protein 298 -2.40757
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 -2.40394
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -2.40298
PSMC3IP PSMC3 interacting protein -2.402
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -2.39766
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.397
WDR4 WD repeat domain 4 -2.39199
ORC6 origin recognition complex, subunit 6 -2.39127
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.38957
CD177 CD177 molecule -2.38643
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.3857
APOBEC3A_B APOBEC3A and APOBEC3B deletion hybrid -2.3852
WDR12 WD repeat domain 12 -2.37885
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.37825
MRPS7 mitochondrial ribosomal protein S7 -2.37585
EXOSC10 exosome component 10 -2.37009
HIRA histone cell cycle regulator -2.36965
DCPS decapping enzyme, scavenger -2.369
EVI2B ecotropic viral integration site 2B -2.36707
GALE UDP-galactose-4-epimerase -2.36132
MYOM2 myomesin 2 -2.36054
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.35773
NFX1 nuclear transcription factor, X-box binding 1 -2.35661
CYREN cell cycle regulator of NHEJ -2.35478
ATRIP ATR interacting protein -2.35261
TEX10 testis expressed 10 -2.35147
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -2.34919
NOP2 NOP2 nucleolar protein -2.34743
PHF11 PHD finger protein 11 -2.34631
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.3394
ZNF512B zinc finger protein 512B -2.33903
CCDC51 coiled-coil domain containing 51 -2.33377
SH3YL1 SH3 and SYLF domain containing 1 -2.33028
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -2.32899
KANK1 KN motif and ankyrin repeat domains 1 -2.32644
SESN1 sestrin 1 -2.32521
ADGRA3 adhesion G protein-coupled receptor A3 -2.32241
NDC1 NDC1 transmembrane nucleoporin -2.32127
CENPF centromere protein F, 350/400kDa -2.31912
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -2.31721
MPHOSPH9 M-phase phosphoprotein 9 -2.31625
INTS15 integrator complex subunit 15 -2.31364
CDC23 cell division cycle 23 -2.31333
PPP1R12A protein phosphatase 1, regulatory subunit 12A -2.30986
EBNA1BP2 EBNA1 binding protein 2 -2.30897
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) -2.30804
RBM28 RNA binding motif protein 28 -2.30211
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.30098
TSSC4 tumor suppressing subtransferable candidate 4 -2.3003
KLHDC4 kelch domain containing 4 -2.30028
IARS1 isoleucyl-tRNA synthetase 1 -2.2998
AKAP8 A kinase (PRKA) anchor protein 8 -2.29924
MRPL4 mitochondrial ribosomal protein L4 -2.29864
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.29851
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -2.2985
MRPL9 mitochondrial ribosomal protein L9 -2.29607
MRPL58 mitochondrial ribosomal protein L58 -2.29441
MFAP5 microfibrillar associated protein 5 -2.29202
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.29153
BYSL bystin-like -2.29017
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -2.28776
REV1 REV1, polymerase (DNA directed) -2.28657
PRR16 proline rich 16 -2.28386
STAG2 stromal antigen 2 -2.28292
SRBD1 S1 RNA binding domain 1 -2.27897
ART3 ADP-ribosyltransferase 3 -2.27701
BAX BCL2-associated X protein -2.27655
UMOD uromodulin -2.2742
STIL SCL/TAL1 interrupting locus -2.27078
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin -2.27051
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -2.26478
CENPU centromere protein U -2.26344
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -2.25246
QTRT1 queuine tRNA-ribosyltransferase 1 -2.25027
UBAP2 ubiquitin associated protein 2 -2.24944
ZNF282 zinc finger protein 282 -2.24939
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.24816
VCP valosin containing protein -2.24699
USP39 ubiquitin specific peptidase 39 -2.2443
CCNJ cyclin J -2.24383
PARP1 poly (ADP-ribose) polymerase 1 -2.24336
NANS N-acetylneuraminic acid synthase -2.24318
RBM38 RNA binding motif protein 38 -2.23784
TBC1D10C TBC1 domain family, member 10C -2.23591
TRDN triadin -2.23449
HLF hepatic leukemia factor -2.23271
RPL39L ribosomal protein L39-like -2.23216
ZNF202 zinc finger protein 202 -2.23018
PTS 6-pyruvoyltetrahydropterin synthase -2.22718
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -2.22625
CKAP2 cytoskeleton associated protein 2 -2.22568
RRP1B ribosomal RNA processing 1B -2.22223
EXOSC9 exosome component 9 -2.22196
RABGGTA Rab geranylgeranyltransferase, alpha subunit -2.21831
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.21789
MCRS1 microspherule protein 1 -2.2168
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -2.21649
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 -2.21594
CNPY3 canopy FGF signaling regulator 3 -2.21168
CLASRP CLK4-associating serine/arginine rich protein -2.20805
ACYP2 acylphosphatase 2, muscle type -2.207
RBM6 RNA binding motif protein 6 -2.20634
DPH2 DPH2 homolog (S. cerevisiae) -2.20497
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) -2.20301
CASC3 cancer susceptibility candidate 3 -2.20158
COQ9 coenzyme Q9 -2.20146
MYL2 myosin, light chain 2, regulatory, cardiac, slow -2.20138
LRRC15 leucine rich repeat containing 15 -2.19955
ATAD2 ATPase family, AAA domain containing 2 -2.19911
MPDU1 mannose-P-dolichol utilization defect 1 -2.19866
SOAT2 sterol O-acyltransferase 2 -2.1982
RSL1D1 ribosomal L1 domain containing 1 -2.19453
EIF4H eukaryotic translation initiation factor 4H -2.19434
PRMT1 protein arginine methyltransferase 1 -2.1921
MYH7 myosin, heavy chain 7, cardiac muscle, beta -2.19091
TUBGCP5 tubulin, gamma complex associated protein 5 -2.18982
HEATR1 HEAT repeat containing 1 -2.18897
EMC6 ER membrane protein complex subunit 6 -2.18876
TLR3 toll-like receptor 3 -2.18803
OSGEP O-sialoglycoprotein endopeptidase -2.18635
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.18572
LSG1 large 60S subunit nuclear export GTPase 1 -2.18431
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.1812
NOL11 nucleolar protein 11 -2.1802
UMPS uridine monophosphate synthetase -2.18009
RPAP3 RNA polymerase II associated protein 3 -2.17673
RGS4 regulator of G-protein signaling 4 -2.17671
FLOT2 flotillin 2 -2.17463
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.17158
POU2AF1 POU class 2 associating factor 1 -2.17078
ELANE elastase, neutrophil expressed -2.17024
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -2.16968
GUSB glucuronidase, beta -2.16681
PMPCA peptidase (mitochondrial processing) alpha -2.16521
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.16451
SPATA5L1 spermatogenesis associated 5-like 1 -2.16374
NCLN nicalin -2.16281
ISOC1 isochorismatase domain containing 1 -2.16056
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein -2.16026
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -2.15907
OTUD4 OTU deubiquitinase 4 -2.15882
HOXA5 homeobox A5 -2.15654
PNN pinin, desmosome associated protein -2.15104
GTPBP8 GTP-binding protein 8 (putative) -2.14896
TRAF3 TNF receptor-associated factor 3 -2.14803
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.14778
GREM2 gremlin 2, DAN family BMP antagonist -2.1453
SPARCL1 SPARC-like 1 (hevin) -2.14508
AFG3L2 AFG3-like AAA ATPase 2 -2.14293
TRAP1 TNF receptor-associated protein 1 -2.14159
NOTCH1 notch 1 -2.13913
KAT5 K(lysine) acetyltransferase 5 -2.13826
DCXR dicarbonyl/L-xylulose reductase -2.13819
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -2.13787
MRPL35 mitochondrial ribosomal protein L35 -2.13637
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -2.13584
GOSR1 golgi SNAP receptor complex member 1 -2.1338
RECQL4 RecQ protein-like 4 -2.13072
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I -2.1294
NFYB nuclear transcription factor Y, beta -2.12823
TRMO tRNA methyltransferase O -2.12698
ZC3H14 zinc finger CCCH-type containing 14 -2.12397
ALG9 ALG9, alpha-1,2-mannosyltransferase -2.12363
PRMT5 protein arginine methyltransferase 5 -2.12352
ACSM2A acyl-CoA synthetase medium-chain family member 2A -2.12305
PRKX protein kinase, X-linked -2.12292
RAB11FIP2 RAB11 family interacting protein 2 (class I) -2.12099
CDCA4 cell division cycle associated 4 -2.12013
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -2.12003
TARDBP TAR DNA binding protein -2.11934
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.11767
SF3B3 splicing factor 3b, subunit 3, 130kDa -2.11752
PA2G4 proliferation-associated 2G4, 38kDa -2.11719
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.11712
TPX2 TPX2, microtubule-associated -2.11591
CLDN8 claudin 8 -2.11574
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -2.11507
INPP5F inositol polyphosphate-5-phosphatase F -2.11372
RAD50 RAD50 homolog (S. cerevisiae) -2.11235
RABEPK Rab9 effector protein with kelch motifs -2.1118
FANCG Fanconi anemia, complementation group G -2.11111
WDR73 WD repeat domain 73 -2.10961
SLC39A1 solute carrier family 39 (zinc transporter), member 1 -2.10838
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -2.10317
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.10202
SEC13 SEC13 homolog (S. cerevisiae) -2.10047
PTER phosphotriesterase related -2.09977
KRI1 KRI1 homolog (S. cerevisiae) -2.09898
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -2.0989
CIRBP cold inducible RNA binding protein -2.09831
KRT13 keratin 13, type I -2.0927
ERC1 ELKS/RAB6-interacting/CAST family member 1 -2.09135
LINS1 lines homolog 1 -2.09011
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -2.08801
LOC102724594 splicing factor U2AF 35 kDa subunit -2.08627
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -2.08122
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -2.08051
FAM169A family with sequence similarity 169, member A -2.07691
XPO1 exportin 1 -2.07657
CEP192 centrosomal protein 192kDa -2.07561
ECPAS Ecm29 proteasome adaptor and scaffold -2.07495
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.07462
TRAF4 TNF receptor-associated factor 4 -2.07431
ZMYND11 zinc finger, MYND-type containing 11 -2.07213
BAZ1B bromodomain adjacent to zinc finger domain, 1B -2.07143
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.07121
MRPS34 mitochondrial ribosomal protein S34 -2.06993
MRPL3 mitochondrial ribosomal protein L3 -2.06812
KIF20B kinesin family member 20B -2.06812
MAT2B methionine adenosyltransferase II, beta -2.06731
CCDC92 coiled-coil domain containing 92 -2.0673
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 -2.06701
SNRPG small nuclear ribonucleoprotein polypeptide G -2.06459
CCT2 chaperonin containing TCP1, subunit 2 (beta) -2.06427
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa -2.06398
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 -2.06325
NUP58 nucleoporin 58 -2.06258
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.06155
PTH1R parathyroid hormone 1 receptor -2.0615
CAAP1 caspase activity and apoptosis inhibitor 1 -2.06116
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -2.06007
MAN2A2 mannosidase, alpha, class 2A, member 2 -2.05948
CDK10 cyclin-dependent kinase 10 -2.05788
ARHGAP19 Rho GTPase activating protein 19 -2.05532
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -2.05446
RIOK2 RIO kinase 2 -2.05437
CENPO centromere protein O -2.05394
PPIF peptidylprolyl isomerase F -2.05321
DDRGK1 DDRGK domain containing 1 -2.05253
TXLNA taxilin alpha -2.05119
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.05117
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.05098
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -2.04845
TNIP2 TNFAIP3 interacting protein 2 -2.04805
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.04459
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -2.04221
ESRP1 epithelial splicing regulatory protein 1 -2.04124
DEK DEK proto-oncogene -2.0399
MTO1 mitochondrial tRNA translation optimization 1 -2.03922
CAND1 cullin-associated and neddylation-dissociated 1 -2.03804
TATDN2 TatD DNase domain containing 2 -2.03763
ZBTB35 zinc finger and BTB domain containing 35 -2.0361
NSUN5 NOP2/Sun domain family, member 5 -2.03574
MAN2C1 mannosidase, alpha, class 2C, member 1 -2.03373
ICAM3 intercellular adhesion molecule 3 -2.03327
AP5S1 adaptor-related protein complex 5, sigma 1 subunit -2.0315
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 -2.03099
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -2.02679
WDR18 WD repeat domain 18 -2.02651
HAUS4 HAUS augmin-like complex, subunit 4 -2.02452
SMC1A structural maintenance of chromosomes 1A -2.02401
COX5A cytochrome c oxidase subunit Va -2.02322
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -2.02285
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.02167
LY6G5C lymphocyte antigen 6 complex, locus G5C -2.02161
SENP6 SUMO1/sentrin specific peptidase 6 -2.02007
HMGN1 high mobility group nucleosome binding domain 1 -2.0199
DARS1 aspartyl-tRNA synthetase 1 -2.01694
HAUS6 HAUS augmin-like complex, subunit 6 -2.01348
CENPQ centromere protein Q -2.01153
TMEM131L transmembrane 131 like -2.00967
RBBP8 retinoblastoma binding protein 8 -2.00844
PMCH pro-melanin-concentrating hormone -2.00754
RSAD2 radical S-adenosyl methionine domain containing 2 -2.00511
ATAD5 ATPase family, AAA domain containing 5 -2.00486
NUP160 nucleoporin 160kDa -2.00386
TTI2 TELO2 interacting protein 2 -2.0026
KCTD9 potassium channel tetramerization domain containing 9 -2.00163
ZNF692 zinc finger protein 692 -2.00139
MTIF2 mitochondrial translational initiation factor 2 -2.00122
HOXB7 homeobox B7 -2.00088