CRCGN016_MCF10A.TP53.M_24H:D11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description rosi with tphp perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:D11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.11281
SATB1 SATB homeobox 1 3.14359
TCEA2 transcription elongation factor A (SII), 2 2.74559
TOMM34 translocase of outer mitochondrial membrane 34 2.37718
AAMDC adipogenesis associated, Mth938 domain containing 2.32473
PKN1 protein kinase N1 2.07629
MCUR1 mitochondrial calcium uniporter regulator 1 2.04206
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.03818

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -4.57348
HMG20B high mobility group 20B -4.37221
THAP11 THAP domain containing 11 -3.43528
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.72608
GADD45B growth arrest and DNA-damage-inducible, beta -2.50165
NPIPA6 nuclear pore complex interacting protein family, member A6 -2.24373
GDF15 growth differentiation factor 15 -2.21552
RELN reelin -2.15303
SCYL3 SCY1-like 3 (S. cerevisiae) -2.15266
SGK1 serum/glucocorticoid regulated kinase 1 -2.10221