CRCGN016_MCF10A.TP53.M_24H:D17 Gene Set
Genes
38 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:D17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STAP2
|
signal transducing adaptor family member 2
|
5.34441
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
3.35005
|
|
COMP
|
cartilage oligomeric matrix protein
|
3.31178
|
|
WIF1
|
WNT inhibitory factor 1
|
2.84651
|
|
METRN
|
meteorin, glial cell differentiation regulator
|
2.64531
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.39969
|
|
IGHMBP2
|
immunoglobulin mu binding protein 2
|
2.24806
|
|
PSMC4
|
proteasome (prosome, macropain) 26S subunit, ATPase, 4
|
2.09191
|
|
BID
|
BH3 interacting domain death agonist
|
2.09018
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.06325
|
|
TMEM14A
|
transmembrane protein 14A
|
2.04508
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.01995
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.87069
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.85371
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-4.81276
|
|
PMM2
|
phosphomannomutase 2
|
-4.62399
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-4.55005
|
|
HMG20B
|
high mobility group 20B
|
-4.53422
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.42642
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.40572
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.32086
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
-3.7887
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.77744
|
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
-3.43304
|
|
TOPBP1
|
topoisomerase (DNA) II binding protein 1
|
-2.6493
|
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
-2.61898
|
|
FASN
|
fatty acid synthase
|
-2.4409
|
|
WARS1
|
tryptophanyl-tRNA synthetase 1
|
-2.39663
|
|
MFSD12
|
major facilitator superfamily domain containing 12
|
-2.38139
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.28743
|
|
TCTA
|
T-cell leukemia translocation altered
|
-2.19584
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.19208
|
|
LAMP3
|
lysosomal-associated membrane protein 3
|
-2.14615
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
-2.09628
|
|
APOO
|
apolipoprotein O
|
-2.09414
|
|
MAOB
|
monoamine oxidase B
|
-2.03698
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.00934
|
|
VEGFD
|
vascular endothelial growth factor D
|
-2.00151
|
