CRCGN016_MCF10A.TP53.M_24H:D20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acronycine 33.54 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

878 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:D20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 9.25236
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 8.92723
MSRA methionine sulfoxide reductase A 8.56047
TP53BP2 tumor protein p53 binding protein 2 8.42543
TICAM1 toll-like receptor adaptor molecule 1 7.60045
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 6.62294
CHIC2 cysteine-rich hydrophobic domain 2 6.5614
SQOR sulfide quinone oxidoreductase 6.37816
RGS2 regulator of G-protein signaling 2 6.23794
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 6.10125
WIF1 WNT inhibitory factor 1 6.02003
SOX4 SRY (sex determining region Y)-box 4 5.8365
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.78395
LRP10 low density lipoprotein receptor-related protein 10 5.4913
GLRX glutaredoxin (thioltransferase) 5.43371
TNIP1 TNFAIP3 interacting protein 1 5.29869
IL1B interleukin 1, beta 4.64278
DUSP4 dual specificity phosphatase 4 4.55268
CDPF1 cysteine-rich, DPF motif domain containing 1 4.53129
TIMP2 TIMP metallopeptidase inhibitor 2 4.41592
SYNGAP1 synaptic Ras GTPase activating protein 1 4.3458
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 4.30468
KCNK1 potassium channel, two pore domain subfamily K, member 1 4.27364
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 4.12767
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.10153
BCL10 B-cell CLL/lymphoma 10 3.99477
VAT1 vesicle amine transport 1 3.97657
CLDN7 claudin 7 3.9344
MINDY1 MINDY lysine 48 deubiquitinase 1 3.91539
IL4R interleukin 4 receptor 3.91149
CLDN4 claudin 4 3.85175
NIT1 nitrilase 1 3.81821
TMBIM1 transmembrane BAX inhibitor motif containing 1 3.81455
IL1A interleukin 1, alpha 3.80866
STAP2 signal transducing adaptor family member 2 3.80503
TSG101 tumor susceptibility 101 3.80242
PRSS8 protease, serine, 8 3.67586
MVP major vault protein 3.65495
TMEM40 transmembrane protein 40 3.64526
OSBPL2 oxysterol binding protein-like 2 3.60815
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.5853
VGLL4 vestigial-like family member 4 3.57188
CORO1A coronin, actin binding protein, 1A 3.54124
GRAMD2B GRAM domain containing 2B 3.52038
HMGA2 high mobility group AT-hook 2 3.45974
WIPI1 WD repeat domain, phosphoinositide interacting 1 3.45151
CCNG2 cyclin G2 3.44614
LYRM1 LYR motif containing 1 3.4261
LSR lipolysis stimulated lipoprotein receptor 3.37505
PLPP2 phospholipid phosphatase 2 3.36585
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 3.36439
QSOX1 quiescin Q6 sulfhydryl oxidase 1 3.36326
GABARAPL2 GABA(A) receptor-associated protein-like 2 3.36044
COMP cartilage oligomeric matrix protein 3.3265
GPR137B G protein-coupled receptor 137B 3.30091
SKIC2 SKI2 subunit of superkiller complex 3.29191
ZFP36 ZFP36 ring finger protein 3.26691
SSH3 slingshot protein phosphatase 3 3.21448
STX5 syntaxin 5 3.20184
PLK3 polo-like kinase 3 3.19703
NECAP2 NECAP endocytosis associated 2 3.18548
HSPB1 heat shock 27kDa protein 1 3.18196
ITPKC inositol-trisphosphate 3-kinase C 3.17149
CTSV cathepsin V 3.17125
SPATA2L spermatogenesis associated 2-like 3.17025
MBOAT2 membrane bound O-acyltransferase domain containing 2 3.13434
USP6NL USP6 N-terminal like 3.12681
CCDC92 coiled-coil domain containing 92 3.12659
RHOG ras homolog family member G 3.12228
ZC3H12A zinc finger CCCH-type containing 12A 3.11605
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.11083
CSNK1E casein kinase 1, epsilon 3.10586
WDR26 WD repeat domain 26 3.09189
WDR44 WD repeat domain 44 3.09169
GCC2 GRIP and coiled-coil domain containing 2 3.08916
PGAP6 post-GPI attachment to proteins 6 3.08555
ATOSB atos homolog B 3.08038
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 3.0776
LRRC8E leucine rich repeat containing 8 family, member E 3.07614
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 3.07002
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 3.05709
IRF9 interferon regulatory factor 9 3.05177
MFGE8 milk fat globule-EGF factor 8 protein 3.04831
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.04643
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 3.03284
MYH9 myosin, heavy chain 9, non-muscle 3.02536
PLAUR plasminogen activator, urokinase receptor 3.0191
CALCOCO1 calcium binding and coiled-coil domain 1 2.99753
NDEL1 nudE neurodevelopment protein 1-like 1 2.98072
DHRS1 dehydrogenase/reductase (SDR family) member 1 2.9752
KRT23 keratin 23, type I 2.95592
STXBP2 syntaxin binding protein 2 2.93429
DUSP14 dual specificity phosphatase 14 2.93309
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.93291
IP6K2 inositol hexakisphosphate kinase 2 2.91667
STX4 syntaxin 4 2.91149
GABARAP GABA(A) receptor-associated protein 2.90675
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.90241
FKBP14 FK506 binding protein 14, 22 kDa 2.89906
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.89268
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.86956
WDTC1 WD and tetratricopeptide repeats 1 2.86401
ACBD3 acyl-CoA binding domain containing 3 2.86106
SDC4 syndecan 4 2.8603
GTPBP2 GTP binding protein 2 2.8572
GDI1 GDP dissociation inhibitor 1 2.85365
FRYL FRY-like 2.85144
CRCT1 cysteine-rich C-terminal 1 2.84736
CSRNP2 cysteine-serine-rich nuclear protein 2 2.84654
MAPK3 mitogen-activated protein kinase 3 2.84484
PLAU plasminogen activator, urokinase 2.84081
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.83589
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 2.82794
TMEM132A transmembrane protein 132A 2.809
TMEM59 transmembrane protein 59 2.80808
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 2.80659
CXCL8 chemokine (C-X-C motif) ligand 8 2.79957
STK17A serine/threonine kinase 17a 2.785
VILL villin-like 2.77861
MMP24OS MMP24 opposite strand 2.77696
MED15 mediator complex subunit 15 2.77219
KIF13B kinesin family member 13B 2.77024
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.75027
UBE2H ubiquitin-conjugating enzyme E2H 2.74812
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 2.73121
G0S2 G0/G1 switch 2 2.7184
TMEM134 transmembrane protein 134 2.70752
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.70676
FEM1C fem-1 homolog c (C. elegans) 2.69395
IRF6 interferon regulatory factor 6 2.69271
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.68616
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.68504
ARMCX3 armadillo repeat containing, X-linked 3 2.68487
MUC13 mucin 13, cell surface associated 2.68407
CANT1 calcium activated nucleotidase 1 2.68211
IER3 immediate early response 3 2.68046
RGS20 regulator of G-protein signaling 20 2.68002
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.67558
WNT7A wingless-type MMTV integration site family, member 7A 2.67054
MYO6 myosin VI 2.64848
ERBB3 erb-b2 receptor tyrosine kinase 3 2.6464
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.64489
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.64271
KLHL9 kelch-like family member 9 2.6364
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.63434
BSDC1 BSD domain containing 1 2.62558
LAMC2 laminin, gamma 2 2.62391
AMOTL2 angiomotin like 2 2.62369
ATP9A ATPase, class II, type 9A 2.61943
EDN1 endothelin 1 2.61709
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 2.61545
OCLN occludin 2.60276
MAGED2 melanoma antigen family D2 2.59993
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 2.59826
TMCC2 transmembrane and coiled-coil domain family 2 2.5964
PLCD1 phospholipase C, delta 1 2.57987
LIN37 lin-37 DREAM MuvB core complex component 2.5757
LAMB3 laminin, beta 3 2.57207
STX7 syntaxin 7 2.56589
CCS copper chaperone for superoxide dismutase 2.56555
STX12 syntaxin 12 2.55468
UPP1 uridine phosphorylase 1 2.55175
ALAS1 5'-aminolevulinate synthase 1 2.54835
ARMCX6 armadillo repeat containing, X-linked 6 2.54796
FOSL1 FOS-like antigen 1 2.54742
OXSR1 oxidative stress responsive 1 2.54714
MMP15 matrix metallopeptidase 15 (membrane-inserted) 2.53438
CHPF2 chondroitin polymerizing factor 2 2.5311
IL32 interleukin 32 2.52912
EPHA2 EPH receptor A2 2.52513
CLUL1 clusterin-like 1 (retinal) 2.52464
VPS9D1 VPS9 domain containing 1 2.52292
TMEM184B transmembrane protein 184B 2.52024
ITPRID2 ITPR interacting domain containing 2 2.51934
AAMDC adipogenesis associated, Mth938 domain containing 2.51831
STYXL1 serine/threonine/tyrosine interacting-like 1 2.517
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.51488
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 2.51469
HMOX1 heme oxygenase 1 2.51219
CRELD1 cysteine-rich with EGF-like domains 1 2.51208
MPST mercaptopyruvate sulfurtransferase 2.51185
IER2 immediate early response 2 2.51045
TMEM265 transmembrane protein 265 2.50951
ETHE1 ethylmalonic encephalopathy 1 2.50637
RNF170 ring finger protein 170 2.50596
GMIP GEM interacting protein 2.50453
ACAA1 acetyl-CoA acyltransferase 1 2.50335
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.49931
ZNF358 zinc finger protein 358 2.49359
ITPKB inositol-trisphosphate 3-kinase B 2.49271
YPEL5 yippee-like 5 (Drosophila) 2.49024
EHD1 EH-domain containing 1 2.48871
IL36G interleukin 36, gamma 2.48497
OPTN optineurin 2.48479
MBD5 methyl-CpG binding domain protein 5 2.48368
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 2.48037
FHL2 four and a half LIM domains 2 2.4779
PCGF3 polycomb group ring finger 3 2.47608
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.47486
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 2.47099
PPCS phosphopantothenoylcysteine synthetase 2.46234
VEGFC vascular endothelial growth factor C 2.46015
ISG20 interferon stimulated exonuclease gene 20kDa 2.45843
ADAP1 ArfGAP with dual PH domains 1 2.45823
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 2.45464
STX8 syntaxin 8 2.45085
MTMR11 myotubularin related protein 11 2.44974
MICU1 mitochondrial calcium uptake 1 2.44821
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 2.44784
TDRD7 tudor domain containing 7 2.44665
PGPEP1 pyroglutamyl-peptidase I 2.44113
PPARD peroxisome proliferator-activated receptor delta 2.43821
FGD6 FYVE, RhoGEF and PH domain containing 6 2.43367
PRSS3 protease, serine, 3 2.42874
YIPF4 Yip1 domain family, member 4 2.42576
PYCARD PYD and CARD domain containing 2.42309
CAMTA2 calmodulin binding transcription activator 2 2.41961
EPS8L2 EPS8-like 2 2.41789
POF1B premature ovarian failure, 1B 2.40671
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.40214
CORO1B coronin, actin binding protein, 1B 2.40007
DBN1 drebrin 1 2.39996
WBP2 WW domain binding protein 2 2.39878
FOXO4 forkhead box O4 2.39744
TRIM31 tripartite motif containing 31 2.38069
KLK10 kallikrein-related peptidase 10 2.38058
RAP1GAP RAP1 GTPase activating protein 2.37922
KDM6B lysine (K)-specific demethylase 6B 2.37913
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.37878
LGALS4 lectin, galactoside-binding, soluble, 4 2.37618
AKTIP AKT interacting protein 2.37581
PRSS22 protease, serine, 22 2.37433
FBN2 fibrillin 2 2.3631
PLPP6 phospholipid phosphatase 6 2.35958
ALS2CL ALS2 C-terminal like 2.35779
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.35693
ITFG1 integrin alpha FG-GAP repeat containing 1 2.35654
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 2.35338
COPB1 coatomer protein complex, subunit beta 1 2.3438
CDA cytidine deaminase 2.33988
CTSB cathepsin B 2.33516
STAU1 staufen double-stranded RNA binding protein 1 2.33405
NEK7 NIMA-related kinase 7 2.33367
TWF2 twinfilin actin binding protein 2 2.32375
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.30903
INPPL1 inositol polyphosphate phosphatase-like 1 2.30629
LMO2 LIM domain only 2 (rhombotin-like 1) 2.30622
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2.3047
BAG6 BCL2-associated athanogene 6 2.30167
UPK1B uroplakin 1B 2.29709
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 2.29644
KDM5C lysine (K)-specific demethylase 5C 2.28924
RSF1 remodeling and spacing factor 1 2.28447
MAGED1 melanoma antigen family D1 2.28015
LLGL2 lethal giant larvae homolog 2 (Drosophila) 2.27942
ACTN4 actinin, alpha 4 2.27746
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 2.27497
NRBF2 nuclear receptor binding factor 2 2.27482
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 2.27098
KRT16 keratin 16, type I 2.27045
LCN2 lipocalin 2 2.26789
RND1 Rho family GTPase 1 2.2659
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.26274
HLA-A major histocompatibility complex, class I, A 2.25509
MINPP1 multiple inositol-polyphosphate phosphatase 1 2.2518
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.25172
AK5 adenylate kinase 5 2.24274
TJP3 tight junction protein 3 2.24234
KIF3B kinesin family member 3B 2.23828
LIF leukemia inhibitory factor 2.23734
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.23424
INAVA innate immunity activator 2.23298
CALB1 calbindin 1, 28kDa 2.23061
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 2.23009
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 2.23009
COL17A1 collagen, type XVII, alpha 1 2.2292
MNMIP1 manchette microtubule inner protein 1 2.22543
NBEAL2 neurobeachin-like 2 2.22321
SAMD9 sterile alpha motif domain containing 9 2.22015
CFLAR CASP8 and FADD-like apoptosis regulator 2.21491
GPR153 G protein-coupled receptor 153 2.21226
RIOK3 RIO kinase 3 2.21204
PPP4C protein phosphatase 4, catalytic subunit 2.20954
ANXA9 annexin A9 2.20747
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 2.2066
RNF2 ring finger protein 2 2.2064
RALGDS ral guanine nucleotide dissociation stimulator 2.20637
IST1 increased sodium tolerance 1 homolog (yeast) 2.20467
MISP mitotic spindle positioning 2.20341
STUM stum, mechanosensory transduction mediator homolog 2.20291
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 2.1992
SLC67A1 solute carrier family 67 member 1 2.19906
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2.19906
HAGH hydroxyacylglutathione hydrolase 2.19226
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 2.19057
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.18972
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 2.17913
ZNF365 zinc finger protein 365 2.17759
DOCK6 dedicator of cytokinesis 6 2.17354
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.17236
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.17197
SCAND1 SCAN domain containing 1 2.16846
INHBA inhibin, beta A 2.16732
CACFD1 calcium channel flower domain containing 1 2.16589
DGKA diacylglycerol kinase, alpha 80kDa 2.16576
CLTB clathrin, light chain B 2.16502
ZNF281 zinc finger protein 281 2.16491
GNL1 guanine nucleotide binding protein-like 1 2.16415
STC1 stanniocalcin 1 2.16101
CHMP5 charged multivesicular body protein 5 2.15852
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2.15699
GASK1B golgi associated kinase 1B 2.15508
ECM1 extracellular matrix protein 1 2.15243
LYPLA2 lysophospholipase II 2.14694
RNF103 ring finger protein 103 2.14668
CLIC4 chloride intracellular channel 4 2.14449
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 2.14443
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 2.14351
GMPPA GDP-mannose pyrophosphorylase A 2.1393
FAM114A1 family with sequence similarity 114, member A1 2.13904
EPS8L1 EPS8-like 1 2.1384
TRADD TNFRSF1A-associated via death domain 2.13731
ITGAV integrin, alpha V 2.13658
TRIB1 tribbles pseudokinase 1 2.13611
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 2.13535
CCDC90B coiled-coil domain containing 90B 2.13324
PDZK1IP1 PDZK1 interacting protein 1 2.13253
SBNO2 strawberry notch homolog 2 (Drosophila) 2.13092
MMP14 matrix metallopeptidase 14 (membrane-inserted) 2.12939
AMPD3 adenosine monophosphate deaminase 3 2.12935
ISG15 ISG15 ubiquitin-like modifier 2.12521
GARRE1 granule associated Rac and RHOG effector 1 2.12468
SDCBP syndecan binding protein (syntenin) 2.12375
PDGFA platelet-derived growth factor alpha polypeptide 2.11932
COXFA4 cytochrome c oxidase associated subunit FA4 2.11674
RAB4B RAB4B, member RAS oncogene family 2.11623
BET1L Bet1 golgi vesicular membrane trafficking protein-like 2.11577
CHMP7 charged multivesicular body protein 7 2.11403
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.11172
TUFT1 tuftelin 1 2.11144
EGR1 early growth response 1 2.10937
S100A12 S100 calcium binding protein A12 2.10796
JUP junction plakoglobin 2.10771
BBC3 BCL2 binding component 3 2.10568
PRKCZ protein kinase C, zeta 2.10479
PTHLH parathyroid hormone-like hormone 2.10414
MSX2 msh homeobox 2 2.10153
CNKSR1 connector enhancer of kinase suppressor of Ras 1 2.10064
LDLRAD4 low density lipoprotein receptor class A domain containing 4 2.10019
MYO1D myosin ID 2.09984
CLCF1 cardiotrophin-like cytokine factor 1 2.09557
FADD Fas (TNFRSF6)-associated via death domain 2.09512
ANKZF1 ankyrin repeat and zinc finger domain containing 1 2.09448
IL22RA1 interleukin 22 receptor, alpha 1 2.0937
ZNF821 zinc finger protein 821 2.08914
IRF7 interferon regulatory factor 7 2.08764
ARPP21 cAMP-regulated phosphoprotein, 21kDa 2.08709
HDLBP high density lipoprotein binding protein 2.08694
ACADVL acyl-CoA dehydrogenase, very long chain 2.08503
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.08307
YIPF3 Yip1 domain family, member 3 2.08089
TM2D1 TM2 domain containing 1 2.07936
CSDC2 cold shock domain containing C2, RNA binding 2.07554
FAM8A1 family with sequence similarity 8, member A1 2.07356
DYNLT3 dynein, light chain, Tctex-type 3 2.07272
SUSD6 sushi domain containing 6 2.07179
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.06881
CCL20 chemokine (C-C motif) ligand 20 2.06843
IGHMBP2 immunoglobulin mu binding protein 2 2.0666
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.06183
CXCL6 chemokine (C-X-C motif) ligand 6 2.06153
PCDH1 protocadherin 1 2.0607
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.05495
OPRPN opiorphin prepropeptide 2.05422
CCND3 cyclin D3 2.0535
CAPN3 calpain 3, (p94) 2.05024
PAOX polyamine oxidase (exo-N4-amino) 2.04922
PLEKHA6 pleckstrin homology domain containing, family A member 6 2.04778
ELF4 E74-like factor 4 (ets domain transcription factor) 2.04746
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.04675
GPC1 glypican 1 2.04441
NPC1 Niemann-Pick disease, type C1 2.04179
BIK BCL2-interacting killer (apoptosis-inducing) 2.04059
PDLIM1 PDZ and LIM domain 1 2.04006
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 2.03782
ZDHHC13 zinc finger, DHHC-type containing 13 2.03438
ROPN1B rhophilin associated tail protein 1B 2.03321
PMP22 peripheral myelin protein 22 2.03176
RBMS2 RNA binding motif, single stranded interacting protein 2 2.03048
PTPN21 protein tyrosine phosphatase, non-receptor type 21 2.02951
RAB9A RAB9A, member RAS oncogene family 2.02914
ZNF688 zinc finger protein 688 2.02862
EFHD1 EF-hand domain family, member D1 2.02695
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.02693
BCAS4 breast carcinoma amplified sequence 4 2.02359
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.02328
CHMP4B charged multivesicular body protein 4B 2.0215
CNIH4 cornichon family AMPA receptor auxiliary protein 4 2.02083
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.0208
PSPN persephin 2.02051
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.0188
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.01546
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.01356
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 2.01323
FOLR3 folate receptor 3 (gamma) 2.01223
WBP1L WW domain binding protein 1-like 2.0102
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 2.00701
LIMK2 LIM domain kinase 2 2.00627
MEF2D myocyte enhancer factor 2D 2.00558
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.00318
SOX10 SRY (sex determining region Y)-box 10 2.00226
HBEGF heparin-binding EGF-like growth factor 2.00042

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -9.14859
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -7.50293
CD320 CD320 molecule -7.49609
CCNB2 cyclin B2 -7.48719
PCNA proliferating cell nuclear antigen -6.65453
TSC22D3 TSC22 domain family, member 3 -6.01822
SH3D19 SH3 domain containing 19 -6.00671
PSRC1 proline/serine-rich coiled-coil 1 -5.93176
CCDC86 coiled-coil domain containing 86 -5.53966
INSIG1 insulin induced gene 1 -5.45276
PARP1 poly (ADP-ribose) polymerase 1 -5.44295
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -5.30828
MCM3 minichromosome maintenance complex component 3 -5.0475
TOP2A topoisomerase (DNA) II alpha 170kDa -5.0044
BIRC5 baculoviral IAP repeat containing 5 -4.89385
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -4.78278
STMN1 stathmin 1 -4.76733
HSPA1A heat shock 70kDa protein 1A -4.74894
KIF20A kinesin family member 20A -4.74495
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.71809
CDC45 cell division cycle 45 -4.62472
MCM10 minichromosome maintenance complex component 10 -4.58804
OIP5 Opa interacting protein 5 -4.54627
NUSAP1 nucleolar and spindle associated protein 1 -4.54568
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -4.44193
CDC6 cell division cycle 6 -4.42305
CDK4 cyclin-dependent kinase 4 -4.41827
NUP133 nucleoporin 133kDa -4.35066
NCAPD3 non-SMC condensin II complex, subunit D3 -4.33917
NEIL3 nei endonuclease VIII-like 3 (E. coli) -4.2798
TSEN2 TSEN2 tRNA splicing endonuclease subunit -4.23963
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.1979
CCNA2 cyclin A2 -4.17807
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.15636
CDC25B cell division cycle 25B -4.08984
SCARB1 scavenger receptor class B, member 1 -4.0488
KIF14 kinesin family member 14 -3.96904
KIF4A kinesin family member 4A -3.94006
ZSCAN5A zinc finger and SCAN domain containing 5A -3.93607
MCM6 minichromosome maintenance complex component 6 -3.90245
NSDHL NAD(P) dependent steroid dehydrogenase-like -3.8739
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.87368
UBE2C ubiquitin-conjugating enzyme E2C -3.86259
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -3.85642
NCAPH non-SMC condensin I complex, subunit H -3.83583
NUP155 nucleoporin 155kDa -3.8142
CDK1 cyclin-dependent kinase 1 -3.81142
ERCC6L excision repair cross-complementation group 6-like -3.80557
FAM216A family with sequence similarity 216, member A -3.76364
YME1L1 YME1-like 1 ATPase -3.74152
WDR3 WD repeat domain 3 -3.72812
TRIP13 thyroid hormone receptor interactor 13 -3.71382
POLR1G RNA polymerase I subunit G -3.69268
NCAPD2 non-SMC condensin I complex, subunit D2 -3.68072
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.67368
ECH1 enoyl CoA hydratase 1, peroxisomal -3.66619
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -3.6428
TMEM97 transmembrane protein 97 -3.64216
PARPBP PARP1 binding protein -3.64009
LBR lamin B receptor -3.59591
DKC1 dyskeratosis congenita 1, dyskerin -3.59543
DERA deoxyribose-phosphate aldolase (putative) -3.59323
UNG uracil-DNA glycosylase -3.57832
IDI1 isopentenyl-diphosphate delta isomerase 1 -3.57414
USP1 ubiquitin specific peptidase 1 -3.56715
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -3.56041
SPC25 SPC25, NDC80 kinetochore complex component -3.52899
KIF15 kinesin family member 15 -3.52314
ANKRD10 ankyrin repeat domain 10 -3.51883
TIMELESS timeless circadian clock -3.50058
SOAT2 sterol O-acyltransferase 2 -3.49634
CDC7 cell division cycle 7 -3.48778
CYCS cytochrome c, somatic -3.45403
CENPA centromere protein A -3.45378
SCML2 sex comb on midleg-like 2 (Drosophila) -3.44541
NOLC1 nucleolar and coiled-body phosphoprotein 1 -3.44499
RFC2 replication factor C (activator 1) 2, 40kDa -3.43273
CDCA3 cell division cycle associated 3 -3.42403
ALDOC aldolase C, fructose-bisphosphate -3.41611
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -3.41145
PLK1 polo-like kinase 1 -3.40512
CISD1 CDGSH iron sulfur domain 1 -3.40116
CCNF cyclin F -3.396
PARP2 poly (ADP-ribose) polymerase 2 -3.39411
TIPIN TIMELESS interacting protein -3.38466
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.37348
NASP nuclear autoantigenic sperm protein (histone-binding) -3.37182
SMC4 structural maintenance of chromosomes 4 -3.35324
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -3.35066
DBF4 DBF4 zinc finger -3.33946
FEN1 flap structure-specific endonuclease 1 -3.3332
FOXM1 forkhead box M1 -3.30989
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -3.30695
FANCI Fanconi anemia, complementation group I -3.30319
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -3.2962
AUNIP aurora kinase A and ninein interacting protein -3.28227
KIF18B kinesin family member 18B -3.27723
ASCC3 activating signal cointegrator 1 complex subunit 3 -3.27237
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.24522
SESN1 sestrin 1 -3.24073
COQ3 coenzyme Q3 methyltransferase -3.23184
AURKA aurora kinase A -3.23097
DEPDC1 DEP domain containing 1 -3.21454
CENPN centromere protein N -3.19453
PRPF4 pre-mRNA processing factor 4 -3.18239
NUP205 nucleoporin 205kDa -3.17527
PRPF31 pre-mRNA processing factor 31 -3.17152
EXO1 exonuclease 1 -3.15126
DUT deoxyuridine triphosphatase -3.15009
TMPO thymopoietin -3.14829
NUP85 nucleoporin 85kDa -3.14426
ACLY ATP citrate lyase -3.13911
ASF1B anti-silencing function 1B histone chaperone -3.13793
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.1359
FANCC Fanconi anemia, complementation group C -3.12568
NAT10 N-acetyltransferase 10 (GCN5-related) -3.12158
ISOC2 isochorismatase domain containing 2 -3.1197
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.11288
SAE1 SUMO1 activating enzyme subunit 1 -3.11243
SKA1 spindle and kinetochore associated complex subunit 1 -3.10751
MCM7 minichromosome maintenance complex component 7 -3.10689
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -3.09081
PRCP prolylcarboxypeptidase (angiotensinase C) -3.08088
TTK TTK protein kinase -3.07916
RACGAP1 Rac GTPase activating protein 1 -3.07044
RFC4 replication factor C (activator 1) 4, 37kDa -3.06976
NCAPG2 non-SMC condensin II complex, subunit G2 -3.06968
PRC1 protein regulator of cytokinesis 1 -3.06669
KIF23 kinesin family member 23 -3.06004
NDC80 NDC80 kinetochore complex component -3.05803
SPDL1 spindle apparatus coiled-coil protein 1 -3.05131
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -3.05022
PGRMC1 progesterone receptor membrane component 1 -3.04937
PSIP1 PC4 and SFRS1 interacting protein 1 -3.03894
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.03803
BRCA1 breast cancer 1, early onset -3.03289
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -3.03054
SQLE squalene epoxidase -3.02303
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -3.00835
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -3.00798
EBNA1BP2 EBNA1 binding protein 2 -2.99041
FKBP5 FK506 binding protein 5 -2.9859
BRIX1 BRX1, biogenesis of ribosomes -2.97099
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.94124
ISOC1 isochorismatase domain containing 1 -2.93888
EXOSC5 exosome component 5 -2.92674
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.9198
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.87926
KIF18A kinesin family member 18A -2.87715
PCOLCE2 procollagen C-endopeptidase enhancer 2 -2.87623
NEK2 NIMA-related kinase 2 -2.87071
HADH hydroxyacyl-CoA dehydrogenase -2.8527
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.852
NOP16 NOP16 nucleolar protein -2.8513
ACOD1 aconitate decarboxylase 1 -2.8455
PUS7 pseudouridylate synthase 7 (putative) -2.83967
SPAG5 sperm associated antigen 5 -2.83488
MPHOSPH9 M-phase phosphoprotein 9 -2.82432
MCM5 minichromosome maintenance complex component 5 -2.82268
IRAK1 interleukin-1 receptor-associated kinase 1 -2.81372
DLAT dihydrolipoamide S-acetyltransferase -2.80392
HLTF helicase-like transcription factor -2.7979
ANGPT1 angiopoietin 1 -2.79634
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -2.79586
GRWD1 glutamate-rich WD repeat containing 1 -2.77206
ANAPC1 anaphase promoting complex subunit 1 -2.76887
CENPE centromere protein E, 312kDa -2.76799
FBXO5 F-box protein 5 -2.76626
PFAS phosphoribosylformylglycinamidine synthase -2.76557
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -2.75979
AURKB aurora kinase B -2.75768
IPO4 importin 4 -2.75466
TSPAN3 tetraspanin 3 -2.75275
UXT ubiquitously-expressed, prefoldin-like chaperone -2.74676
MCMBP minichromosome maintenance complex binding protein -2.74653
MRPS2 mitochondrial ribosomal protein S2 -2.73837
APIP APAF1 interacting protein -2.73686
HSPA14 heat shock 70kDa protein 14 -2.7326
PHGDH phosphoglycerate dehydrogenase -2.72499
MRPL3 mitochondrial ribosomal protein L3 -2.72316
CHEK1 checkpoint kinase 1 -2.72203
DNA2 DNA replication helicase/nuclease 2 -2.72156
PIMREG PICALM interacting mitotic regulator -2.71549
UNC119B unc-119 homolog B (C. elegans) -2.7089
CDCA8 cell division cycle associated 8 -2.70848
NUP62 nucleoporin 62kDa -2.70776
RIOX1 ribosomal oxygenase 1 -2.69821
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.69366
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.68895
ARHGAP11A Rho GTPase activating protein 11A -2.68765
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.68384
PBK PDZ binding kinase -2.65911
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.64628
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.64351
TATDN2 TatD DNase domain containing 2 -2.62912
HMGB2 high mobility group box 2 -2.62593
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.62523
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.62517
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.61491
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.60999
DHCR7 7-dehydrocholesterol reductase -2.60682
TUBA3E tubulin, alpha 3e -2.60398
RBL1 retinoblastoma-like 1 -2.60216
TK1 thymidine kinase 1, soluble -2.59243
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -2.58454
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -2.58348
MYO19 myosin XIX -2.57856
INTS14 integrator complex subunit 14 -2.57645
PRMT1 protein arginine methyltransferase 1 -2.57218
OAT ornithine aminotransferase -2.57217
RAD51C RAD51 paralog C -2.56741
HOXA5 homeobox A5 -2.56703
KDM5D lysine (K)-specific demethylase 5D -2.56656
ENTR1 endosome associated trafficking regulator 1 -2.56571
GMNN geminin, DNA replication inhibitor -2.56321
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.56142
PGAM4 phosphoglycerate mutase family member 4 -2.55886
CDC25C cell division cycle 25C -2.55722
ZBTB24 zinc finger and BTB domain containing 24 -2.5556
WDR12 WD repeat domain 12 -2.55306
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.54933
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.54632
CBR1 carbonyl reductase 1 -2.54444
MEPCE methylphosphate capping enzyme -2.5347
HEATR3 HEAT repeat containing 3 -2.53421
NPR2 natriuretic peptide receptor 2 -2.52303
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -2.52177
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.52086
TMX2 thioredoxin-related transmembrane protein 2 -2.5201
TFAM transcription factor A, mitochondrial -2.51923
KIF11 kinesin family member 11 -2.51821
ACACA acetyl-CoA carboxylase alpha -2.51768
DNM1 dynamin 1 -2.5174
PRDX4 peroxiredoxin 4 -2.50659
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.49741
BLM Bloom syndrome, RecQ helicase-like -2.49325
OXA1L oxidase (cytochrome c) assembly 1-like -2.48606
GPD1L glycerol-3-phosphate dehydrogenase 1-like -2.48192
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -2.47933
APOO apolipoprotein O -2.47422
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.47113
TRIM28 tripartite motif containing 28 -2.47033
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.47006
EXOSC9 exosome component 9 -2.46912
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.46841
WDR77 WD repeat domain 77 -2.46504
TARP TCR gamma alternate reading frame protein -2.45553
NR1H2 nuclear receptor subfamily 1, group H, member 2 -2.45162
CENPU centromere protein U -2.4466
MRPL34 mitochondrial ribosomal protein L34 -2.44186
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.43927
SRSF2 serine/arginine-rich splicing factor 2 -2.43715
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.43712
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -2.43605
FADS2 fatty acid desaturase 2 -2.4355
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.43538
CDC25A cell division cycle 25A -2.43048
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -2.42922
COA7 cytochrome c oxidase assembly factor 7 (putative) -2.42913
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 -2.42385
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.42029
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.41927
MIS18A MIS18 kinetochore protein A -2.41793
RGPD2 RANBP2-like and GRIP domain containing 2 -2.41421
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.41331
RPP40 ribonuclease P/MRP 40kDa subunit -2.40959
DHCR24 24-dehydrocholesterol reductase -2.40653
SNRPA small nuclear ribonucleoprotein polypeptide A -2.40571
MTPAP mitochondrial poly(A) polymerase -2.40561
RAD51 RAD51 recombinase -2.4055
DSN1 DSN1, MIS12 kinetochore complex component -2.40269
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.40113
TROAP trophinin associated protein -2.39605
AK8 adenylate kinase 8 -2.39568
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.39481
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.39125
CDC20 cell division cycle 20 -2.38976
ASTN2 astrotactin 2 -2.38829
THAP11 THAP domain containing 11 -2.3855
KPTN kaptin (actin binding protein) -2.38008
NT5DC2 5'-nucleotidase domain containing 2 -2.37883
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.37746
RPP25 ribonuclease P/MRP 25kDa subunit -2.37514
CEP55 centrosomal protein 55kDa -2.37485
RUSC1 RUN and SH3 domain containing 1 -2.37428
SNRPF small nuclear ribonucleoprotein polypeptide F -2.3735
ALG3 ALG3, alpha-1,3- mannosyltransferase -2.37311
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -2.37137
TOE1 target of EGR1, member 1 (nuclear) -2.36807
TWNK twinkle mtDNA helicase -2.36625
WBP11 WW domain binding protein 11 -2.36377
FBL fibrillarin -2.35706
CCNB1 cyclin B1 -2.35484
NOL8 nucleolar protein 8 -2.35106
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.34908
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.34495
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.34439
GLB1L2 galactosidase, beta 1-like 2 -2.34202
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.33984
KLK2 kallikrein-related peptidase 2 -2.33606
RFC3 replication factor C (activator 1) 3, 38kDa -2.3349
TMEM39B transmembrane protein 39B -2.33324
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.33136
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.33127
MSTO1 misato 1, mitochondrial distribution and morphology regulator -2.32955
DSCC1 DNA replication and sister chromatid cohesion 1 -2.32876
CKS1B CDC28 protein kinase regulatory subunit 1B -2.32807
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.32762
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.32733
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.32498
PRPF19 pre-mRNA processing factor 19 -2.32419
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 -2.32413
UBIAD1 UbiA prenyltransferase domain containing 1 -2.32372
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.32144
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.32019
PUS1 pseudouridylate synthase 1 -2.31835
ALG9 ALG9, alpha-1,2-mannosyltransferase -2.31611
LAP3 leucine aminopeptidase 3 -2.31474
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.31168
NUP93 nucleoporin 93kDa -2.30747
DCK deoxycytidine kinase -2.30549
CDKN3 cyclin-dependent kinase inhibitor 3 -2.30378
COIL coilin -2.30376
UBE2S ubiquitin-conjugating enzyme E2S -2.2899
RIOX2 ribosomal oxygenase 2 -2.28848
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.28837
STAC SH3 and cysteine rich domain -2.28768
NUP37 nucleoporin 37kDa -2.28626
CCDC15 coiled-coil domain containing 15 -2.27837
CTCF CCCTC-binding factor (zinc finger protein) -2.26966
SCML1 sex comb on midleg-like 1 (Drosophila) -2.26944
TCERG1 transcription elongation regulator 1 -2.26892
BZW2 basic leucine zipper and W2 domains 2 -2.26404
MRPL12 mitochondrial ribosomal protein L12 -2.26389
LAS1L LAS1-like (S. cerevisiae) -2.26263
GEMIN4 gem (nuclear organelle) associated protein 4 -2.25365
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -2.25279
LSM12 LSM12 homolog (S. cerevisiae) -2.25233
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.25083
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.25006
CTPS1 CTP synthase 1 -2.24997
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.24881
TTC27 tetratricopeptide repeat domain 27 -2.24848
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.24789
MKI67 marker of proliferation Ki-67 -2.24749
RABEPK Rab9 effector protein with kelch motifs -2.24457
RASA4B RAS p21 protein activator 4B -2.24431
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.24411
SFTPD surfactant protein D -2.24145
NUP160 nucleoporin 160kDa -2.24081
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.23893
CENPS-CORT CENPS-CORT readthrough -2.23866
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -2.23673
TBP TATA box binding protein -2.23194
HAUS7 HAUS augmin-like complex, subunit 7 -2.2261
CHODL chondrolectin -2.22352
WDR70 WD repeat domain 70 -2.22332
ZNF274 zinc finger protein 274 -2.22319
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.22052
RRM1 ribonucleotide reductase M1 -2.21731
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 -2.21602
MCM4 minichromosome maintenance complex component 4 -2.21362
PCCB propionyl CoA carboxylase, beta polypeptide -2.21011
COL4A2 collagen, type IV, alpha 2 -2.20572
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.20435
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.20142
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -2.18953
LMNB1 lamin B1 -2.18761
IPO5 importin 5 -2.18588
CENPI centromere protein I -2.18426
SLC35F2 solute carrier family 35, member F2 -2.18267
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -2.18258
TUBGCP3 tubulin, gamma complex associated protein 3 -2.17861
SSRP1 structure specific recognition protein 1 -2.17746
BORA bora, aurora kinase A activator -2.17623
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.17264
KIAA0586 KIAA0586 -2.16871
ZWILCH zwilch kinetochore protein -2.16807
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.16765
COASY CoA synthase -2.16499
TUBGCP5 tubulin, gamma complex associated protein 5 -2.16391
IPO9 importin 9 -2.16313
GRSF1 G-rich RNA sequence binding factor 1 -2.16098
POLR3B polymerase (RNA) III (DNA directed) polypeptide B -2.16047
RBM14-RBM4 RBM14-RBM4 readthrough -2.16016
HJURP Holliday junction recognition protein -2.15779
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.15773
SEPHS1 selenophosphate synthetase 1 -2.15657
ZDHHC6 zinc finger, DHHC-type containing 6 -2.15263
CENPM centromere protein M -2.15169
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.15122
TUBGCP4 tubulin, gamma complex associated protein 4 -2.15085
TPX2 TPX2, microtubule-associated -2.14913
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.14838
CLCC1 chloride channel CLIC-like 1 -2.14637
ATF5 activating transcription factor 5 -2.14564
ATP5F1B ATP synthase F1 subunit beta -2.14368
TCTN3 tectonic family member 3 -2.14065
ZWINT ZW10 interacting kinetochore protein -2.14032
ACSL1 acyl-CoA synthetase long-chain family member 1 -2.13221
PPT1 palmitoyl-protein thioesterase 1 -2.1322
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.13145
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) -2.13097
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -2.13034
ZBTB35 zinc finger and BTB domain containing 35 -2.12955
ICE2 interactor of little elongation complex ELL subunit 2 -2.12899
PLK4 polo-like kinase 4 -2.12896
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.12895
CDCA4 cell division cycle associated 4 -2.12438
DPH2 DPH2 homolog (S. cerevisiae) -2.12365
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.12193
MPC2 mitochondrial pyruvate carrier 2 -2.12069
SRFBP1 serum response factor binding protein 1 -2.11806
YEATS4 YEATS domain containing 4 -2.11767
MTA2 metastasis associated 1 family, member 2 -2.11597
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.11567
SORD sorbitol dehydrogenase -2.11499
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -2.10872
FAM184A family with sequence similarity 184, member A -2.10837
ZNF473 zinc finger protein 473 -2.10146
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.0984
CRY1 cryptochrome circadian clock 1 -2.09704
MIS18BP1 MIS18 binding protein 1 -2.09561
FXN frataxin -2.09485
EIF4A3 eukaryotic translation initiation factor 4A3 -2.0933
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -2.08915
EXOSC2 exosome component 2 -2.08891
DROSHA drosha, ribonuclease type III -2.08571
EXOSC8 exosome component 8 -2.0849
ANOS1 anosmin 1 -2.08037
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.07976
RSU1 Ras suppressor protein 1 -2.07826
ZNF551 zinc finger protein 551 -2.07131
MSH2 mutS homolog 2 -2.07043
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.06551
TRA2B transformer 2 beta homolog (Drosophila) -2.06133
FASTKD3 FAST kinase domains 3 -2.05967
PRMT3 protein arginine methyltransferase 3 -2.0587
CCP110 centriolar coiled coil protein 110kDa -2.05612
GMPS guanine monphosphate synthase -2.05561
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.0554
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.05312
SYPL1 synaptophysin-like 1 -2.04594
PGC progastricsin (pepsinogen C) -2.04278
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.03605
KIF20B kinesin family member 20B -2.03509
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.03048
SRSF1 serine/arginine-rich splicing factor 1 -2.02883
NDC1 NDC1 transmembrane nucleoporin -2.02717
CCDC102B coiled-coil domain containing 102B -2.02392
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.02158
MRPS34 mitochondrial ribosomal protein S34 -2.02152
RAD54L RAD54-like (S. cerevisiae) -2.01871
INTS7 integrator complex subunit 7 -2.01801
CEP85 centrosomal protein 85kDa -2.01624
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -2.01334
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -2.01327
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.01272
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.01261
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -2.01113
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.00906
HMGN2 high mobility group nucleosomal binding domain 2 -2.00685
SRPRB signal recognition particle receptor, B subunit -2.00418
PA2G4 proliferation-associated 2G4, 38kDa -2.0025
RNFT2 ring finger protein, transmembrane 2 -2.00168
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.00047