CRCGN016_MCF10A.TP53.M_24H:D22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description picloram, technical grade 102.29 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:D22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHMP6 charged multivesicular body protein 6 4.98669
MAP7 microtubule-associated protein 7 3.91486
FGFR4 fibroblast growth factor receptor 4 2.97053
STAP2 signal transducing adaptor family member 2 2.8689
PYCR1 pyrroline-5-carboxylate reductase 1 2.84457
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.0768

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -5.63593
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -5.3143
MT2A metallothionein 2A -5.12926
MT1X metallothionein 1X -3.77512
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.36459
DVL3 dishevelled segment polarity protein 3 -2.85719
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -2.85476
HMG20B high mobility group 20B -2.79792
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.69661
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -2.60157
MSN moesin -2.48395
CD320 CD320 molecule -2.4563
RNF167 ring finger protein 167 -2.33854
PCNA proliferating cell nuclear antigen -2.30688
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -2.18184
CTNND1 catenin (cadherin-associated protein), delta 1 -2.14927
MAGEF1 melanoma antigen family F1 -2.08145
HSPA1A heat shock 70kDa protein 1A -2.06397
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.0225