CRCGN016_MCF10A.TP53.M_24H:D23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description picloram, technical grade 34.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ARID5B AT rich interactive domain 5B (MRF1-like) 4.70008
SPAG4 sperm associated antigen 4 3.49436
AGR2 anterior gradient 2 3.0581
MAP7 microtubule-associated protein 7 2.92825
MAMLD1 mastermind-like domain containing 1 2.82446
CNRIP1 cannabinoid receptor interacting protein 1 2.62485
ALDOC aldolase C, fructose-bisphosphate 2.2211
CCP110 centriolar coiled coil protein 110kDa 2.20035
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.1327
STX1A syntaxin 1A (brain) 2.02823
GPR171 G protein-coupled receptor 171 2.01998

decreased expression

Symbol Name Standardized Value
CYCS cytochrome c, somatic -5.14807
HSPA1A heat shock 70kDa protein 1A -4.77817
CCNB2 cyclin B2 -3.60166
NPDC1 neural proliferation, differentiation and control, 1 -3.48015
COTL1 coactosin-like F-actin binding protein 1 -3.33794
THAP11 THAP domain containing 11 -3.15549
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.96575
ADI1 acireductone dioxygenase 1 -2.66693
PRPF4 pre-mRNA processing factor 4 -2.47826
MTERF3 mitochondrial transcription termination factor 3 -2.32229
NVL nuclear VCP-like -2.21578
GGCT gamma-glutamylcyclotransferase -2.14959
ACO2 aconitase 2, mitochondrial -2.04866