CRCGN016_MCF10A.TP53.M_24H:E02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description indole 33.82 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 3.31565
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.90131
KLHL21 kelch-like family member 21 2.86634
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.63121
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.0808
TMEM186 transmembrane protein 186 2.06066
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.04955

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.75065
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.99618
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.40218
THAP11 THAP domain containing 11 -2.27854
MRPS2 mitochondrial ribosomal protein S2 -2.26799
CLTB clathrin, light chain B -2.25987
UBE2A ubiquitin-conjugating enzyme E2A -2.24605
CORO1A coronin, actin binding protein, 1A -2.179
RGS2 regulator of G-protein signaling 2 -2.06127