CRCGN016_MCF10A.TP53.M_24H:E03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description indole 11.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL2 chemokine (C-X-C motif) ligand 2 4.90488
ABHD6 abhydrolase domain containing 6 4.6092
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.09516
ACAA1 acetyl-CoA acyltransferase 1 3.13432
ATP11B ATPase, class VI, type 11B 2.91081
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.58338
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.41241
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.34978
NGRN neugrin, neurite outgrowth associated 2.27257
DNASE1L3 deoxyribonuclease I-like 3 2.18686
CIB1 calcium and integrin binding 1 (calmyrin) 2.1014
CISD1 CDGSH iron sulfur domain 1 2.09039
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.03096
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) 2.01257
MZT2A mitotic spindle organizing protein 2A 2.00602

decreased expression

Symbol Name Standardized Value
C2CD5 C2 calcium-dependent domain containing 5 -3.8223
PSIP1 PC4 and SFRS1 interacting protein 1 -3.25083
IFRD2 interferon-related developmental regulator 2 -3.08714
SLC35B1 solute carrier family 35, member B1 -2.34104
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -2.28519
RFC2 replication factor C (activator 1) 2, 40kDa -2.28019
BASP1 brain abundant, membrane attached signal protein 1 -2.24988
SERF1A small EDRK-rich factor 1A (telomeric) -2.11194