CRCGN016_MCF10A.TP53.M_24H:E04 Gene Set
Genes
31 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LAGE3
|
L antigen family, member 3
|
4.47082
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
3.49541
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
3.25919
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.1957
|
|
NUCB2
|
nucleobindin 2
|
2.9454
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.71967
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.46638
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.23735
|
|
ACBD3
|
acyl-CoA binding domain containing 3
|
2.20067
|
|
UBL4A
|
ubiquitin-like 4A
|
2.12
|
|
DFFA
|
DNA fragmentation factor, 45kDa, alpha polypeptide
|
2.08047
|
|
KCNH2
|
potassium channel, voltage gated eag related subfamily H, member 2
|
2.05336
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PGAM4
|
phosphoglycerate mutase family member 4
|
-4.27531
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-3.58011
|
|
ENOPH1
|
enolase-phosphatase 1
|
-3.56678
|
|
VAT1
|
vesicle amine transport 1
|
-3.54043
|
|
MSN
|
moesin
|
-3.4137
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-3.23777
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.20841
|
|
GOLT1B
|
golgi transport 1B
|
-3.11453
|
|
HMG20B
|
high mobility group 20B
|
-3.11409
|
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
-3.09843
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-2.90221
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
-2.76766
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-2.70523
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-2.32594
|
|
ASCC3
|
activating signal cointegrator 1 complex subunit 3
|
-2.2798
|
|
ANXA2
|
annexin A2
|
-2.157
|
|
PTTG1IP
|
pituitary tumor-transforming 1 interacting protein
|
-2.14857
|
|
GABPA
|
GA binding protein transcription factor, alpha subunit 60kDa
|
-2.13604
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
-2.09657
|
