CRCGN016_MCF10A.TP53.M_24H:E05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diphenyl-p-phenylenediamine 33.49 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HBA1 hemoglobin, alpha 1 5.6747
HBB hemoglobin, beta 4.21439
IGHMBP2 immunoglobulin mu binding protein 2 2.87838
KDM5D lysine (K)-specific demethylase 5D 2.53135
FAT1 FAT atypical cadherin 1 2.40609
CEP57 centrosomal protein 57kDa 2.22358
AGR2 anterior gradient 2 2.19442
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.19177
THAP12 THAP domain containing 12 2.04094

decreased expression

Symbol Name Standardized Value
DYNLT3 dynein, light chain, Tctex-type 3 -5.55951
CCDC86 coiled-coil domain containing 86 -4.25418
YME1L1 YME1-like 1 ATPase -3.58497
SMC1A structural maintenance of chromosomes 1A -2.82861
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.69135
RPIA ribose 5-phosphate isomerase A -2.63175
CDC20 cell division cycle 20 -2.57692
RBM34 RNA binding motif protein 34 -2.36746
XPO7 exportin 7 -2.23769
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.22724
RALGDS ral guanine nucleotide dissociation stimulator -2.21429
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.18969
PUDP pseudouridine 5'-phosphatase -2.12777
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 -2.0044