CRCGN016_MCF10A.TP53.M_24H:E07 Gene Set
Genes
33 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SPAG4
|
sperm associated antigen 4
|
6.31549
|
|
WIF1
|
WNT inhibitory factor 1
|
3.50849
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.8466
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.43986
|
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
|
2.1879
|
|
MSX1
|
msh homeobox 1
|
2.10692
|
|
SGCB
|
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
|
2.06142
|
|
PSMB3
|
proteasome (prosome, macropain) subunit, beta type, 3
|
2.05114
|
|
RMND1
|
required for meiotic nuclear division 1 homolog (S. cerevisiae)
|
2.03231
|
|
ATP1B3
|
ATPase, Na+/K+ transporting, beta 3 polypeptide
|
2.01074
|
|
AMZ2
|
archaelysin family metallopeptidase 2
|
2.00566
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MSMO1
|
methylsterol monooxygenase 1
|
-6.3699
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-6.17375
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-3.16868
|
|
TMEM267
|
transmembrane protein 267
|
-2.83557
|
|
DROSHA
|
drosha, ribonuclease type III
|
-2.71828
|
|
IGFBP7
|
insulin-like growth factor binding protein 7
|
-2.65699
|
|
RBM12B
|
RNA binding motif protein 12B
|
-2.62967
|
|
PAIP1
|
poly(A) binding protein interacting protein 1
|
-2.55996
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.52901
|
|
TSPAN4
|
tetraspanin 4
|
-2.49973
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
-2.48862
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.39445
|
|
DHCR24
|
24-dehydrocholesterol reductase
|
-2.32731
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-2.27781
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-2.22917
|
|
ZNHIT6
|
zinc finger, HIT-type containing 6
|
-2.20436
|
|
FCGR3B
|
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
|
-2.15474
|
|
WDR70
|
WD repeat domain 70
|
-2.13212
|
|
DUSP10
|
dual specificity phosphatase 10
|
-2.12372
|
|
CD47
|
CD47 molecule
|
-2.10083
|
|
PFN1
|
profilin 1
|
-2.06681
|
|
LINC02762
|
long intergenic non-protein coding RNA 2762
|
-2.04885
|
