CRCGN016_MCF10A.TP53.M_24H:E09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3'-dimethylbenzidine.2hcl 11.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

25 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STIMATE STIM activating enhancer 6.42716
ADGRE5 adhesion G protein-coupled receptor E5 4.78498
IGHMBP2 immunoglobulin mu binding protein 2 3.53809
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.5221
LRP5 low density lipoprotein receptor-related protein 5 2.2331
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 2.16836
SAMHD1 SAM domain and HD domain 1 2.12585
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.06766
FGFR4 fibroblast growth factor receptor 4 2.03125

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -5.07323
MSMO1 methylsterol monooxygenase 1 -4.58361
CDC20 cell division cycle 20 -4.58361
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.14571
RALGDS ral guanine nucleotide dissociation stimulator -3.19144
SMC1A structural maintenance of chromosomes 1A -2.83039
TIMP1 TIMP metallopeptidase inhibitor 1 -2.82157
ELOVL1 ELOVL fatty acid elongase 1 -2.77999
HMGB2 high mobility group box 2 -2.60513
TOR1A torsin family 1, member A (torsin A) -2.30411
MCM6 minichromosome maintenance complex component 6 -2.28549
ZWINT ZW10 interacting kinetochore protein -2.18777
ZNF10 zinc finger protein 10 -2.17922
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.10074
EPCIP exosomal polycystin 1 interacting protein -2.05028
ACSS3 acyl-CoA synthetase short-chain family member 3 -2.00241