CRCGN016_MCF10A.TP53.M_24H:E11 Gene Set
Genes
58 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
4.30849
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
4.25382
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
3.89846
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.80677
|
|
CDC25B
|
cell division cycle 25B
|
3.17645
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
3.12315
|
|
IDE
|
insulin-degrading enzyme
|
2.85242
|
|
CADM1
|
cell adhesion molecule 1
|
2.64203
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.59103
|
|
SATB1
|
SATB homeobox 1
|
2.53891
|
|
BRD9
|
bromodomain containing 9
|
2.5261
|
|
TMEM222
|
transmembrane protein 222
|
2.31128
|
|
AGR2
|
anterior gradient 2
|
2.28441
|
|
TLCD3A
|
TLC domain containing 3A
|
2.26975
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
2.25092
|
|
YBX3
|
Y box binding protein 3
|
2.21601
|
|
MSRA
|
methionine sulfoxide reductase A
|
2.17758
|
|
SNX11
|
sorting nexin 11
|
2.1708
|
|
TOM1
|
target of myb1 (chicken)
|
2.16846
|
|
BLCAP
|
bladder cancer associated protein
|
2.16513
|
|
TRAP1
|
TNF receptor-associated protein 1
|
2.13284
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.13185
|
|
DNM1
|
dynamin 1
|
2.1271
|
|
SLC1A4
|
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
|
2.12534
|
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
2.10363
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.0539
|
|
TNFRSF1A
|
tumor necrosis factor receptor superfamily, member 1A
|
2.05328
|
|
MLC1
|
megalencephalic leukoencephalopathy with subcortical cysts 1
|
2.04205
|
|
MCOLN1
|
mucolipin 1
|
2.02681
|
|
KCTD5
|
potassium channel tetramerization domain containing 5
|
2.01127
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.00109
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MSMO1
|
methylsterol monooxygenase 1
|
-4.58749
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.5597
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.29644
|
|
ISOC1
|
isochorismatase domain containing 1
|
-2.95642
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-2.77373
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.74572
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.65141
|
|
DNAJB4
|
DnaJ (Hsp40) homolog, subfamily B, member 4
|
-2.63872
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-2.62447
|
|
RCOR3
|
REST corepressor 3
|
-2.53617
|
|
JMJD6
|
jumonji domain containing 6
|
-2.47527
|
|
TES
|
testin LIM domain protein
|
-2.43702
|
|
THBS1
|
thrombospondin 1
|
-2.33211
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
-2.21229
|
|
ADA2
|
adenosine deaminase 2
|
-2.20258
|
|
PTGER2
|
prostaglandin E receptor 2 (subtype EP2), 53kDa
|
-2.17903
|
|
KPNA5
|
karyopherin alpha 5 (importin alpha 6)
|
-2.15867
|
|
INSIG1
|
insulin induced gene 1
|
-2.15041
|
|
PRPSAP2
|
phosphoribosyl pyrophosphate synthetase-associated protein 2
|
-2.1439
|
|
LXN
|
latexin
|
-2.11963
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.11468
|
|
LPAR6
|
lysophosphatidic acid receptor 6
|
-2.1135
|
|
ARFGEF1
|
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
|
-2.06075
|
|
TOPBP1
|
topoisomerase (DNA) II binding protein 1
|
-2.03717
|
|
MAPK7
|
mitogen-activated protein kinase 7
|
-2.03005
|
|
FOXH1
|
forkhead box H1
|
-2.00882
|
|
GDF3
|
growth differentiation factor 3
|
-2.00863
|
