CRCGN016_MCF10A.TP53.M_24H:E12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phenyl-b-naphthylamine 11.16 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HBA1 hemoglobin, alpha 1 3.52875
FKBP14 FK506 binding protein 14, 22 kDa 3.51381
GPER1 G protein-coupled estrogen receptor 1 3.3624
GATA2 GATA binding protein 2 3.17889
MAMLD1 mastermind-like domain containing 1 2.95398
C2CD2 C2 calcium-dependent domain containing 2 2.91572
HBB hemoglobin, beta 2.507
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.43988
BACE2 beta-site APP-cleaving enzyme 2 2.33956
CENPE centromere protein E, 312kDa 2.23122

decreased expression

Symbol Name Standardized Value
KIF20A kinesin family member 20A -3.354
LAP3 leucine aminopeptidase 3 -3.27298
MRPS2 mitochondrial ribosomal protein S2 -3.16217
TUBB6 tubulin, beta 6 class V -3.00813
COTL1 coactosin-like F-actin binding protein 1 -2.97493
PAEP progestagen-associated endometrial protein -2.72831
HMG20B high mobility group 20B -2.67607
DCK deoxycytidine kinase -2.48244
KRT14 keratin 14, type I -2.37896
KDM3A lysine (K)-specific demethylase 3A -2.34983
UBAC1 UBA domain containing 1 -2.32842
HEBP1 heme binding protein 1 -2.13156
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.0424