CRCGN016_MCF10A.TP53.M_24H:E13 Gene Set
Genes
39 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
5.07261
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.06883
|
|
DHX29
|
DEAH (Asp-Glu-Ala-His) box polypeptide 29
|
3.61785
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
3.45717
|
|
KIF5C
|
kinesin family member 5C
|
3.45061
|
|
TLR4
|
toll-like receptor 4
|
3.30358
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
3.09981
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.89394
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.86109
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.86003
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.60365
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
2.56113
|
|
IKBKB
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
|
2.46191
|
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
2.45938
|
|
STK10
|
serine/threonine kinase 10
|
2.44148
|
|
SV2B
|
synaptic vesicle glycoprotein 2B
|
2.1724
|
|
ZNF384
|
zinc finger protein 384
|
2.15018
|
|
IQGAP1
|
IQ motif containing GTPase activating protein 1
|
2.14994
|
|
FRS2
|
fibroblast growth factor receptor substrate 2
|
2.05943
|
|
GSK3B
|
glycogen synthase kinase 3 beta
|
2.04047
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.97482
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.81012
|
|
COG2
|
component of oligomeric golgi complex 2
|
-3.75019
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
-3.28857
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-3.20751
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-3.08738
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-2.96663
|
|
KIF20A
|
kinesin family member 20A
|
-2.92446
|
|
UNC50
|
unc-50 homolog (C. elegans)
|
-2.82956
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.66432
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
-2.54938
|
|
HLA-DOB
|
major histocompatibility complex, class II, DO beta
|
-2.27438
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-2.18162
|
|
E2F5
|
E2F transcription factor 5, p130-binding
|
-2.18024
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.15228
|
|
PSMB9
|
proteasome (prosome, macropain) subunit, beta type, 9
|
-2.148
|
|
COX5B
|
cytochrome c oxidase subunit Vb
|
-2.14299
|
|
TMEM121
|
transmembrane protein 121
|
-2.12574
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.05247
|
