CRCGN016_MCF10A.TP53.M_24H:E15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description g-butyrolactone 10.99 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

10 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FGFR4 fibroblast growth factor receptor 4 4.19347
ADAM10 ADAM metallopeptidase domain 10 3.77016
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 3.7444
MELK maternal embryonic leucine zipper kinase 2.23315
MMP1 matrix metallopeptidase 1 2.08637

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -4.90788
PCCB propionyl CoA carboxylase, beta polypeptide -2.64162
EIF5 eukaryotic translation initiation factor 5 -2.16971
GRN granulin -2.16155
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.14807