CRCGN016_MCF10A.TP53.M_24H:E17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinyl acetate 34.67 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

684 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LGMN legumain 6.0205
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 5.97348
SSBP2 single-stranded DNA binding protein 2 5.83535
TSEN2 TSEN2 tRNA splicing endonuclease subunit 5.31641
PPARG peroxisome proliferator-activated receptor gamma 5.27231
TBXA2R thromboxane A2 receptor 3.41423
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 3.20679
INSL3 insulin-like 3 (Leydig cell) 3.1608
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.14818
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 3.1233
MTUS2 microtubule associated tumor suppressor candidate 2 3.12046
RELN reelin 3.05255
SYK spleen tyrosine kinase 3.02307
RYR2 ryanodine receptor 2 (cardiac) 3.0066
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.99782
C5 complement component 5 2.99598
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 2.95564
CLDN11 claudin 11 2.9461
TERT telomerase reverse transcriptase 2.93302
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.90477
SPDEF SAM pointed domain containing ETS transcription factor 2.86405
ZBTB44 zinc finger and BTB domain containing 44 2.85728
UPK2 uroplakin 2 2.84356
FHL5 four and a half LIM domains 5 2.8301
FAIM Fas apoptotic inhibitory molecule 2.81462
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 2.81013
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 2.80458
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.7937
EPB41L5 erythrocyte membrane protein band 4.1 like 5 2.78664
DLX6 distal-less homeobox 6 2.78599
MAGIX MAGI family member, X-linked 2.7761
BMP4 bone morphogenetic protein 4 2.76864
GSTM5 glutathione S-transferase mu 5 2.74396
GPER1 G protein-coupled estrogen receptor 1 2.72185
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.71682
VSIG10 V-set and immunoglobulin domain containing 10 2.7143
CDX4 caudal type homeobox 4 2.70243
CRYGD crystallin, gamma D 2.69933
DRP2 dystrophin related protein 2 2.69285
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.68928
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.68031
UBQLN2 ubiquilin 2 2.65031
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 2.64179
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.64132
LYN LYN proto-oncogene, Src family tyrosine kinase 2.63832
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2.62951
NRXN3 neurexin 3 2.62798
TUBA8 tubulin, alpha 8 2.61766
OR5I1 olfactory receptor, family 5, subfamily I, member 1 2.61139
STARD3 StAR-related lipid transfer (START) domain containing 3 2.59107
SP4 Sp4 transcription factor 2.59084
FSD1 fibronectin type III and SPRY domain containing 1 2.59074
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 2.58916
CCN5 cellular communication network factor 5 2.58849
ZNF507 zinc finger protein 507 2.58787
OR52A1 olfactory receptor, family 52, subfamily A, member 1 2.58648
RRH retinal pigment epithelium-derived rhodopsin homolog 2.5859
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.58546
TBL1Y transducin (beta)-like 1, Y-linked 2.58446
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.57719
RAG1 recombination activating gene 1 2.57195
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 2.57072
S100A5 S100 calcium binding protein A5 2.57019
DOCK5 dedicator of cytokinesis 5 2.55883
IFNA7 interferon, alpha 7 2.54799
TAS2R16 taste receptor, type 2, member 16 2.53976
INHA inhibin, alpha 2.53546
NIPSNAP3B nipsnap homolog 3B (C. elegans) 2.53383
PCDHB1 protocadherin beta 1 2.52529
AKAP5 A kinase (PRKA) anchor protein 5 2.51951
FAM204A family with sequence similarity 204, member A 2.51592
NOL10 nucleolar protein 10 2.50986
DNAH2 dynein, axonemal, heavy chain 2 2.50619
CD163L1 CD163 molecule-like 1 2.50394
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.50389
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 2.50342
MED31 mediator complex subunit 31 2.50083
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.50042
ATG10 autophagy related 10 2.49997
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 2.49543
IFNA10 interferon, alpha 10 2.49209
TAAR2 trace amine associated receptor 2 2.49126
ZNF549 zinc finger protein 549 2.49112
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 2.49035
VAV3 vav 3 guanine nucleotide exchange factor 2.48962
KLK14 kallikrein-related peptidase 14 2.48723
GCM1 glial cells missing homolog 1 (Drosophila) 2.4841
ZNF221 zinc finger protein 221 2.48263
SULT4A1 sulfotransferase family 4A, member 1 2.48242
FOXH1 forkhead box H1 2.47352
ODAD2 outer dynein arm docking complex subunit 2 2.46979
TENM1 teneurin transmembrane protein 1 2.46775
LCT lactase 2.46183
OR10H3 olfactory receptor, family 10, subfamily H, member 3 2.46182
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 2.46126
FGF20 fibroblast growth factor 20 2.45977
FPGT-TNNI3K FPGT-TNNI3K readthrough 2.45934
MTMR10 myotubularin related protein 10 2.45563
CA7 carbonic anhydrase VII 2.45011
CCNA1 cyclin A1 2.44943
FNDC8 fibronectin type III domain containing 8 2.4491
MAP7D3 MAP7 domain containing 3 2.44869
ZIC4 Zic family member 4 2.44535
SHOX short stature homeobox 2.44407
CRHR2 corticotropin releasing hormone receptor 2 2.44231
GNG3 guanine nucleotide binding protein (G protein), gamma 3 2.4419
ASCL3 achaete-scute family bHLH transcription factor 3 2.44026
ENTREP2 endosomal transmembrane epsin interactor 2 2.43741
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 2.43297
IHH indian hedgehog 2.43288
PRAMEF12 PRAME family member 12 2.43241
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.43026
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 2.42759
HID1 HID1 domain containing 2.42735
ZNF721 zinc finger protein 721 2.42397
NMBR neuromedin B receptor 2.4228
ZFR2 zinc finger RNA binding protein 2 2.42153
RAG2 recombination activating gene 2 2.41902
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 2.41765
OMP olfactory marker protein 2.41727
TRPC7 transient receptor potential cation channel, subfamily C, member 7 2.41449
SNCG synuclein, gamma (breast cancer-specific protein 1) 2.41348
CPED1 cadherin-like and PC-esterase domain containing 1 2.41192
QPCTL glutaminyl-peptide cyclotransferase-like 2.40654
EFR3B EFR3 homolog B (S. cerevisiae) 2.40622
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 2.40581
TRIM49B tripartite motif containing 49B 2.40397
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 2.40099
IFNA16 interferon, alpha 16 2.40035
CSH2 chorionic somatomammotropin hormone 2 2.40015
ANKRD44 ankyrin repeat domain 44 2.39997
PCDHA2 protocadherin alpha 2 2.39429
SMIM41 small integral membrane protein 41 2.39367
SCN4A sodium channel, voltage gated, type IV alpha subunit 2.39287
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 2.39163
HYOU1 hypoxia up-regulated 1 2.39086
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 2.39005
DCAF4 DDB1 and CUL4 associated factor 4 2.39001
PRDM9 PR domain containing 9 2.38912
GLRA2 glycine receptor, alpha 2 2.38894
CHRM5 cholinergic receptor, muscarinic 5 2.38748
CTIF CBP80/20-dependent translation initiation factor 2.38474
COLEC10 collectin sub-family member 10 (C-type lectin) 2.38077
TCL1B T-cell leukemia/lymphoma 1B 2.37863
SYN3 synapsin III 2.37715
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 2.3759
TTBK2 tau tubulin kinase 2 2.3756
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.37557
CBX2 chromobox homolog 2 2.3746
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 2.37436
CCDC82 coiled-coil domain containing 82 2.37319
ADAM21 ADAM metallopeptidase domain 21 2.37295
ANKRD34C ankyrin repeat domain 34C 2.37259
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.36914
ADPRH ADP-ribosylarginine hydrolase 2.36801
LHCGR luteinizing hormone/choriogonadotropin receptor 2.3671
THRB thyroid hormone receptor, beta 2.3663
H2BC3 H2B clustered histone 3 2.366
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 2.36139
FAM174B family with sequence similarity 174, member B 2.36079
TCP10L t-complex 10-like 2.35843
FGF8 fibroblast growth factor 8 (androgen-induced) 2.35797
TBX6 T-box 6 2.35432
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 2.35347
TEX13A testis expressed 13A 2.35302
KRT33B keratin 33B, type I 2.35051
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 2.34878
UNC5C unc-5 homolog C (C. elegans) 2.34445
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 2.34177
OR1E2 olfactory receptor, family 1, subfamily E, member 2 2.34165
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 2.34134
FRAS1 Fraser extracellular matrix complex subunit 1 2.339
ONECUT2 one cut homeobox 2 2.33723
TMLHE trimethyllysine hydroxylase, epsilon 2.33593
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.3355
PGR progesterone receptor 2.3353
GATA3 GATA binding protein 3 2.33466
ZNF343 zinc finger protein 343 2.33405
RERGL RERG/RAS-like 2.33382
FAM131B family with sequence similarity 131, member B 2.33232
VPS50 VPS50 subunit of EARP/GARPII complex 2.33222
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 2.32833
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.32766
UNC13A unc-13 homolog A (C. elegans) 2.32537
ASXL3 additional sex combs like transcriptional regulator 3 2.32457
CHP2 calcineurin-like EF-hand protein 2 2.32354
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2.32348
SPATA31A3 SPATA31 subfamily A, member 3 2.32059
IQSEC3 IQ motif and Sec7 domain 3 2.31886
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.3185
CBLN1 cerebellin 1 precursor 2.31624
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 2.31617
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 2.31495
NSUN7 NOP2/Sun domain family, member 7 2.31197
MIMS2 mitochondrial inner membrane scaffold 2 2.31155
CNTNAP3B contactin associated protein-like 3B 2.3106
GUCY2F guanylate cyclase 2F, retinal 2.31044
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.31001
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.30851
NSD3 nuclear receptor binding SET domain protein 3 2.3077
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 2.3074
SIGLEC5 sialic acid binding Ig-like lectin 5 2.30626
TRMT9B tRNA methyltransferase 9B (putative) 2.30609
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.30395
PKD2L2 polycystic kidney disease 2-like 2 2.3028
CAMK1G calcium/calmodulin-dependent protein kinase IG 2.30226
SIRPB1 signal-regulatory protein beta 1 2.30142
GPR52 G protein-coupled receptor 52 2.30041
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 2.29946
MTMR14 myotubularin related protein 14 2.29753
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 2.29427
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 2.29418
PSG2 pregnancy specific beta-1-glycoprotein 2 2.29259
GPR75 G protein-coupled receptor 75 2.29065
SYN1 synapsin I 2.28693
TEC tec protein tyrosine kinase 2.2852
ERN2 endoplasmic reticulum to nucleus signaling 2 2.285
WDR7 WD repeat domain 7 2.2849
NOX3 NADPH oxidase 3 2.28423
HRH4 histamine receptor H4 2.28354
OR2W1 olfactory receptor, family 2, subfamily W, member 1 2.2828
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 2.28265
NPY4R2 neuropeptide Y receptor Y4-2 2.28208
CER1 cerberus 1, DAN family BMP antagonist 2.28149
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 2.27834
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 2.27777
TAS2R8 taste receptor, type 2, member 8 2.27743
CT55 cancer/testis antigen 55 2.27722
PHF13 PHD finger protein 13 2.27583
CSDC2 cold shock domain containing C2, RNA binding 2.27555
SYNGR3 synaptogyrin 3 2.2729
ZNF157 zinc finger protein 157 2.27216
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.27202
FAM246A family with sequence similarity 246 member A 2.27164
ELAC1 elaC ribonuclease Z 1 2.27124
FAM76A family with sequence similarity 76, member A 2.27076
STS steroid sulfatase (microsomal), isozyme S 2.27059
EDN2 endothelin 2 2.27013
NYX nyctalopin 2.26966
TSBP1 testis expressed basic protein 1 2.26907
RGS7 regulator of G-protein signaling 7 2.26839
ZNF235 zinc finger protein 235 2.26817
GPR50 G protein-coupled receptor 50 2.26656
ACAA1 acetyl-CoA acyltransferase 1 2.26431
CEND1 cell cycle exit and neuronal differentiation 1 2.26372
TRIM49D2 tripartite motif containing 49D2 2.26348
TAS2R3 taste receptor, type 2, member 3 2.26346
ADGRE3 adhesion G protein-coupled receptor E3 2.26294
ZNF385D zinc finger protein 385D 2.26071
EFCAB6 EF-hand calcium binding domain 6 2.26035
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.25976
FOXL2 forkhead box L2 2.25975
GSTT4 glutathione S-transferase theta 4 2.25949
GRM1 glutamate receptor, metabotropic 1 2.25859
TEX28 testis expressed 28 2.25637
ARHGAP44 Rho GTPase activating protein 44 2.25553
PHAF1 phagosome assembly factor 1 2.25074
FAM120C family with sequence similarity 120C 2.2503
FAM184A family with sequence similarity 184, member A 2.24962
OR2B2 olfactory receptor, family 2, subfamily B, member 2 2.24879
TAS2R4 taste receptor, type 2, member 4 2.24457
WRNIP1 Werner helicase interacting protein 1 2.2423
TMEM212 transmembrane protein 212 2.2406
PARP11 poly (ADP-ribose) polymerase family, member 11 2.23624
GPR85 G protein-coupled receptor 85 2.23606
ZNF639 zinc finger protein 639 2.23481
GPRASP1 G protein-coupled receptor associated sorting protein 1 2.2346
KIF25 kinesin family member 25 2.2339
SHH sonic hedgehog 2.23346
KMT2D lysine (K)-specific methyltransferase 2D 2.23267
NEUROD2 neuronal differentiation 2 2.23121
FZD1 frizzled class receptor 1 2.22987
GML glycosylphosphatidylinositol anchored molecule like 2.22941
CSHL1 chorionic somatomammotropin hormone-like 1 2.22819
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 2.22802
ZFYVE9 zinc finger, FYVE domain containing 9 2.22783
PRAMEF13 PRAME family member 13 2.22725
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.22533
TAAR5 trace amine associated receptor 5 2.2253
RASL11B RAS-like, family 11, member B 2.22252
CA5B carbonic anhydrase VB, mitochondrial 2.22228
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.22073
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.22031
GPR6 G protein-coupled receptor 6 2.22028
CCDC177 coiled-coil domain containing 177 2.21904
ZNF586 zinc finger protein 586 2.21847
LCOR ligand dependent nuclear receptor corepressor 2.21773
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 2.21752
TESC tescalcin 2.21714
GATA4 GATA binding protein 4 2.21631
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 2.21571
RGSL1 regulator of G-protein signaling like 1 2.21343
MTSS2 MTSS I-BAR domain containing 2 2.21201
KRT83 keratin 83, type II 2.21149
OCM2 oncomodulin 2 2.21113
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.21091
NABP1 nucleic acid binding protein 1 2.21084
CNKSR2 connector enhancer of kinase suppressor of Ras 2 2.21071
HTATSF1 HIV-1 Tat specific factor 1 2.21025
FRRS1L ferric-chelate reductase 1-like 2.21004
IL16 interleukin 16 2.20939
LPCAT3 lysophosphatidylcholine acyltransferase 3 2.20745
IRGC immunity-related GTPase family, cinema 2.20692
HOXC5 homeobox C5 2.20675
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 2.20623
MRPS18C mitochondrial ribosomal protein S18C 2.20532
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 2.20519
SPRYD7 SPRY domain containing 7 2.20478
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 2.20232
PRDM5 PR domain containing 5 2.20175
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.20174
TRHR thyrotropin-releasing hormone receptor 2.20117
HMHB1 histocompatibility (minor) HB-1 2.20116
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.20105
KRT38 keratin 38, type I 2.20021
SOX2 SRY (sex determining region Y)-box 2 2.19993
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.19991
RXFP3 relaxin/insulin-like family peptide receptor 3 2.19868
ZNF548 zinc finger protein 548 2.19863
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.19821
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 2.19706
H2AJ H2A.J histone 2.19633
FGF4 fibroblast growth factor 4 2.19575
RIT2 Ras-like without CAAX 2 2.19558
DKK4 dickkopf WNT signaling pathway inhibitor 4 2.19453
SNAP25 synaptosomal-associated protein, 25kDa 2.19448
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 2.19437
FAM13C family with sequence similarity 13, member C 2.1935
EYA3 EYA transcriptional coactivator and phosphatase 3 2.19205
OR7A17 olfactory receptor, family 7, subfamily A, member 17 2.19179
SYT13 synaptotagmin XIII 2.18989
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 2.18952
TLR6 toll-like receptor 6 2.18908
TNP2 transition protein 2 (during histone to protamine replacement) 2.18784
CETN1 centrin, EF-hand protein, 1 2.18749
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 2.18312
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.18296
FSHR follicle stimulating hormone receptor 2.18194
OR2B6 olfactory receptor, family 2, subfamily B, member 6 2.1813
ISL1 ISL LIM homeobox 1 2.17951
CA4 carbonic anhydrase IV 2.1784
UPK1A uroplakin 1A 2.17653
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 2.17636
OR1A2 olfactory receptor, family 1, subfamily A, member 2 2.17633
FLT3LG fms-related tyrosine kinase 3 ligand 2.17547
PRSS16 protease, serine, 16 (thymus) 2.17538
POM121L2 POM121 transmembrane nucleoporin-like 2 2.17477
INO80D INO80 complex subunit D 2.17456
IL22 interleukin 22 2.17399
PAX4 paired box 4 2.17395
PRR15L proline rich 15-like 2.17382
TAS2R9 taste receptor, type 2, member 9 2.17378
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.17334
CST8 cystatin 8 (cystatin-related epididymal specific) 2.17243
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 2.17228
PRICKLE3 prickle homolog 3 (Drosophila) 2.17193
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.17081
APOE apolipoprotein E 2.17018
TMC7 transmembrane channel-like 7 2.16969
VRTN vertebrae development associated 2.16774
ONECUT1 one cut homeobox 1 2.16738
OR1A1 olfactory receptor, family 1, subfamily A, member 1 2.1664
THAP9 THAP domain containing 9 2.1644
MCF2 MCF.2 cell line derived transforming sequence 2.16382
KCTD17 potassium channel tetramerization domain containing 17 2.16349
H3-4 H3.4 histone, cluster member 2.16319
OR7C1 olfactory receptor, family 7, subfamily C, member 1 2.16318
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 2.16105
GRM3 glutamate receptor, metabotropic 3 2.158
GJB4 gap junction protein, beta 4, 30.3kDa 2.15749
CDADC1 cytidine and dCMP deaminase domain containing 1 2.15687
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.15345
ADAM20 ADAM metallopeptidase domain 20 2.15305
IFT46 intraflagellar transport 46 2.15234
S1PR2 sphingosine-1-phosphate receptor 2 2.15147
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 2.15114
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2.14961
ADCY6 adenylate cyclase 6 2.14844
NEU3 sialidase 3 (membrane sialidase) 2.14838
KLHDC8A kelch domain containing 8A 2.14791
PSG11 pregnancy specific beta-1-glycoprotein 11 2.14759
ZNF816 zinc finger protein 816 2.14719
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 2.14685
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 2.14527
LHX3 LIM homeobox 3 2.14494
FSTL4 follistatin-like 4 2.14458
ENTREP1 endosomal transmembrane epsin interactor 1 2.14392
RAB40A RAB40A, member RAS oncogene family 2.14256
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 2.1413
VN1R1 vomeronasal 1 receptor 1 2.13839
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 2.1378
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 2.13683
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 2.13403
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.13239
MAPK10 mitogen-activated protein kinase 10 2.13236
LGALS12 lectin, galactoside-binding, soluble, 12 2.13216
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 2.13173
CRYGA crystallin, gamma A 2.13107
SLIT3 slit homolog 3 (Drosophila) 2.13045
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.12983
PDE12 phosphodiesterase 12 2.12908
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 2.12901
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.12819
ZNF225 zinc finger protein 225 2.12787
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 2.12768
OR10J1 olfactory receptor, family 10, subfamily J, member 1 2.12745
ADAM11 ADAM metallopeptidase domain 11 2.12649
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 2.12558
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.12476
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 2.12436
BCL2L11 BCL2-like 11 (apoptosis facilitator) 2.12258
BTG4 B-cell translocation gene 4 2.12233
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 2.12229
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 2.12217
CFAP74 cilia and flagella associated protein 74 2.12133
CEP41 centrosomal protein 41kDa 2.12068
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 2.1205
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 2.12042
MTNR1B melatonin receptor 1B 2.12007
HIGD1B HIG1 hypoxia inducible domain family, member 1B 2.11971
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.11857
GHRH growth hormone releasing hormone 2.11651
IFNA5 interferon, alpha 5 2.11605
SCN10A sodium channel, voltage gated, type X alpha subunit 2.1149
PDZD7 PDZ domain containing 7 2.11461
SCN7A sodium channel, voltage gated, type VII alpha subunit 2.11444
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.11399
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 2.1139
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 2.11375
RGS11 regulator of G-protein signaling 11 2.11264
DNAH6 dynein, axonemal, heavy chain 6 2.11205
IFNA21 interferon, alpha 21 2.11193
KRTAP2-3 keratin associated protein 2-3 2.11075
CATSPERH catsper channel auxiliary subunit eta 2.11068
CPQ carboxypeptidase Q 2.11031
GP6 glycoprotein VI (platelet) 2.10997
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 2.10883
TMEM151B transmembrane protein 151B 2.10717
RFX4 regulatory factor X, 4 (influences HLA class II expression) 2.10657
LONRF3 LON peptidase N-terminal domain and ring finger 3 2.10518
DPF3 D4, zinc and double PHD fingers, family 3 2.10463
TMEM101 transmembrane protein 101 2.10289
NRIP2 nuclear receptor interacting protein 2 2.10269
LOC100996750 keratin-associated protein 4-7 2.10184
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.10099
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 2.10004
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.09994
ZBTB33 zinc finger and BTB domain containing 33 2.09858
ARHGAP26 Rho GTPase activating protein 26 2.09855
UTF1 undifferentiated embryonic cell transcription factor 1 2.09851
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 2.09815
BTNL2 butyrophilin-like 2 2.09812
HPCAL4 hippocalcin like 4 2.09732
ZNF550 zinc finger protein 550 2.09688
CD101 CD101 molecule 2.09643
PLA2G5 phospholipase A2, group V 2.09606
ABHD14A abhydrolase domain containing 14A 2.09502
NOTCH4 notch 4 2.09366
ZFP91 ZFP91 zinc finger protein 2.09366
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.09354
TSNAXIP1 translin-associated factor X interacting protein 1 2.09337
OR3A3 olfactory receptor, family 3, subfamily A, member 3 2.09293
SCN2A sodium channel, voltage gated, type II alpha subunit 2.09262
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 2.09089
CCDC57 coiled-coil domain containing 57 2.09064
DCAF13 DDB1 and CUL4 associated factor 13 2.0896
SPO11 SPO11 meiotic protein covalently bound to DSB 2.0893
RPA4 replication protein A4, 30kDa 2.08767
KNL1 kinetochore scaffold 1 2.08756
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 2.08725
ACRV1 acrosomal vesicle protein 1 2.0865
TMEM143 transmembrane protein 143 2.08601
SPATA1 spermatogenesis associated 1 2.08475
SNAP91 synaptosomal-associated protein, 91kDa 2.08297
SPACA1 sperm acrosome associated 1 2.08257
GFM1 G elongation factor, mitochondrial 1 2.08236
RIMS1 regulating synaptic membrane exocytosis 1 2.08153
FBXO24 F-box protein 24 2.08116
NLGN4X neuroligin 4, X-linked 2.08092
PCDHA3 protocadherin alpha 3 2.08026
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 2.0802
PTGDR2 prostaglandin D2 receptor 2 2.07976
CXCR1 chemokine (C-X-C motif) receptor 1 2.07974
KRT3 keratin 3, type II 2.07971
GPR45 G protein-coupled receptor 45 2.07949
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 2.07913
EMC10 ER membrane protein complex subunit 10 2.07837
NANOG Nanog homeobox 2.07703
MAGEB3 melanoma antigen family B3 2.07584
GNRHR gonadotropin-releasing hormone receptor 2.07582
LOC124903372 uncharacterized LOC124903372 2.07572
ARHGAP24 Rho GTPase activating protein 24 2.07564
LINS1 lines homolog 1 2.07557
ZNF613 zinc finger protein 613 2.07438
PURG purine-rich element binding protein G 2.07427
TBC1D22B TBC1 domain family, member 22B 2.07355
IREB2 iron-responsive element binding protein 2 2.07273
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.07173
ZNF471 zinc finger protein 471 2.07138
ETV3 ets variant 3 2.06976
FN3K fructosamine 3 kinase 2.0696
STON1-GTF2A1L STON1-GTF2A1L readthrough 2.0695
GDAP2 ganglioside induced differentiation associated protein 2 2.06937
GPR27 G protein-coupled receptor 27 2.06907
CASS4 Cas scaffolding protein family member 4 2.06808
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 2.0677
ZNF835 zinc finger protein 835 2.0677
PSG4 pregnancy specific beta-1-glycoprotein 4 2.06682
LOC128966601 pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial-like 2.06531
ACSL5 acyl-CoA synthetase long-chain family member 5 2.06458
OLFML1 olfactomedin-like 1 2.0644
MC5R melanocortin 5 receptor 2.06406
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 2.064
FAM135A family with sequence similarity 135, member A 2.06331
SOCS4 suppressor of cytokine signaling 4 2.06319
FRMPD4 FERM and PDZ domain containing 4 2.06293
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 2.0626
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 2.06202
SSX3 synovial sarcoma, X breakpoint 3 2.06187
GTPBP10 GTP-binding protein 10 (putative) 2.06133
TLL2 tolloid-like 2 2.06049
PARM1 prostate androgen-regulated mucin-like protein 1 2.06011
FLT4 fms-related tyrosine kinase 4 2.05877
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.05845
DOT1L DOT1-like histone H3K79 methyltransferase 2.05686
HROB homologous recombination factor with OB-fold 2.05604
TIMP2 TIMP metallopeptidase inhibitor 2 2.05393
OR10H2 olfactory receptor, family 10, subfamily H, member 2 2.05392
SIX3 SIX homeobox 3 2.05326
CDKL5 cyclin-dependent kinase-like 5 2.05298
PSG3 pregnancy specific beta-1-glycoprotein 3 2.05272
NAXE NAD(P)HX epimerase 2.05182
LY6G5C lymphocyte antigen 6 complex, locus G5C 2.05153
SLC4A3 solute carrier family 4 (anion exchanger), member 3 2.05083
CABP2 calcium binding protein 2 2.05082
FPR2 formyl peptide receptor 2 2.05057
CDH9 cadherin 9, type 2 (T1-cadherin) 2.05044
DRD3 dopamine receptor D3 2.04953
ZNF493 zinc finger protein 493 2.04935
SPIN2A spindlin family, member 2A 2.04904
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 2.04884
TRAIP TRAF interacting protein 2.04878
ECEL1 endothelin converting enzyme-like 1 2.04834
LGI1 leucine-rich, glioma inactivated 1 2.04819
OSGEP O-sialoglycoprotein endopeptidase 2.04811
GRIA3 glutamate receptor, ionotropic, AMPA 3 2.04793
H2AP H2A.P histone 2.04737
GPR63 G protein-coupled receptor 63 2.04597
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 2.04557
GJA8 gap junction protein, alpha 8, 50kDa 2.04507
CD1B CD1b molecule 2.04423
VIPR2 vasoactive intestinal peptide receptor 2 2.04418
GREB1 growth regulation by estrogen in breast cancer 1 2.04403
CPLX2 complexin 2 2.04362
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 2.04342
ASMT acetylserotonin O-methyltransferase 2.04336
LMX1B LIM homeobox transcription factor 1, beta 2.04295
ADCY10 adenylate cyclase 10 (soluble) 2.0428
POU3F4 POU class 3 homeobox 4 2.04246
ZSCAN12 zinc finger and SCAN domain containing 12 2.04117
GRK1 G protein-coupled receptor kinase 1 2.04073
MYO15A myosin XVA 2.04003
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 2.03976
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 2.03962
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 2.0388
INPP5J inositol polyphosphate-5-phosphatase J 2.03832
GPR31 G protein-coupled receptor 31 2.03812
GREB1L growth regulation by estrogen in breast cancer-like 2.03784
OR11A1 olfactory receptor, family 11, subfamily A, member 1 2.03758
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.0372
EDN3 endothelin 3 2.03652
PLA2G2E phospholipase A2, group IIE 2.03618
BTN1A1 butyrophilin, subfamily 1, member A1 2.0361
H1-1 H1.1 linker histone, cluster member 2.03516
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 2.03495
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 2.03493
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 2.0341
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 2.03395
EYA1 EYA transcriptional coactivator and phosphatase 1 2.03392
NPAS1 neuronal PAS domain protein 1 2.03372
NEUROD4 neuronal differentiation 4 2.03354
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 2.03352
TREML2 triggering receptor expressed on myeloid cells-like 2 2.03347
LOC102723713 TP53-target gene 3 protein 2.03288
BMP15 bone morphogenetic protein 15 2.03231
C5AR2 complement component 5a receptor 2 2.03172
PTTG2 pituitary tumor-transforming 2 2.03165
SCAI suppressor of cancer cell invasion 2.03125
BICDL1 BICD family like cargo adaptor 1 2.0309
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 2.03024
TRAF3IP2 TRAF3 interacting protein 2 2.03017
RAD51D RAD51 paralog D 2.03004
CDH20 cadherin 20, type 2 2.03
NPHP1 nephronophthisis 1 (juvenile) 2.02969
KLHL1 kelch-like family member 1 2.02935
NTN3 netrin 3 2.02836
PCSK5 proprotein convertase subtilisin/kexin type 5 2.02831
CCIN calicin 2.02783
IMPG2 interphotoreceptor matrix proteoglycan 2 2.02772
BCL2 B-cell CLL/lymphoma 2 2.02732
ZNF391 zinc finger protein 391 2.02679
STEEP1 STING1 ER exit protein 1 2.0264
OR10H1 olfactory receptor, family 10, subfamily H, member 1 2.02638
TRPV1 transient receptor potential cation channel, subfamily V, member 1 2.02632
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.02479
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 2.02452
TRIM10 tripartite motif containing 10 2.02437
HPSE2 heparanase 2 (inactive) 2.0238
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 2.02372
ZNF253 zinc finger protein 253 2.02372
TEX13B testis expressed 13B 2.02212
HRH3 histamine receptor H3 2.02188
ZNF324B zinc finger protein 324B 2.02144
DGKE diacylglycerol kinase, epsilon 64kDa 2.02074
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 2.01948
LYZL6 lysozyme-like 6 2.01946
TRPC6 transient receptor potential cation channel, subfamily C, member 6 2.01939
IFT54 intraflagellar transport 54 2.01879
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 2.01845
TSPO2 translocator protein 2 2.01794
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 2.01669
PTPN9 protein tyrosine phosphatase, non-receptor type 9 2.01643
KRT37 keratin 37, type I 2.01636
KIF5A kinesin family member 5A 2.01515
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 2.01494
AFF2 AF4/FMR2 family, member 2 2.01486
PMFBP1 polyamine modulated factor 1 binding protein 1 2.01348
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2.01322
RFX3 regulatory factor X, 3 (influences HLA class II expression) 2.0132
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2.01296
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 2.01288
GRM7 glutamate receptor, metabotropic 7 2.0127
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.01223
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 2.0113
SSX5 synovial sarcoma, X breakpoint 5 2.01122
LEP leptin 2.01062
ZNF236 zinc finger protein 236 2.01002
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 2.00993
RNF122 ring finger protein 122 2.00769
SLITRK2 SLIT and NTRK-like family, member 2 2.0066
H2BC15 H2B clustered histone 15 2.00582
MMP26 matrix metallopeptidase 26 2.00578
SLC22A14 solute carrier family 22, member 14 2.00556
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 2.00551
SPIDR scaffolding protein involved in DNA repair 2.00504
OPRL1 opiate receptor-like 1 2.00485
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.00463
CD200R1 CD200 receptor 1 2.0043
ADAM30 ADAM metallopeptidase domain 30 2.0042
ZNF460 zinc finger protein 460 2.00355
DCSTAMP dendrocyte expressed seven transmembrane protein 2.00354
AMHR2 anti-Mullerian hormone receptor, type II 2.0035
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 2.00307
NAGLU N-acetylglucosaminidase, alpha 2.00276
OPRM1 opioid receptor, mu 1 2.00096
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 2.00055
GLP1R glucagon-like peptide 1 receptor 2.00026

decreased expression

Symbol Name Standardized Value
DERA deoxyribose-phosphate aldolase (putative) -4.9993
KIF20A kinesin family member 20A -4.83031
LAP3 leucine aminopeptidase 3 -4.42222
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -4.04014
CD320 CD320 molecule -3.76889
CAB39 calcium binding protein 39 -3.67356
PCCB propionyl CoA carboxylase, beta polypeptide -3.55354
PCNA proliferating cell nuclear antigen -2.70769
DDB2 damage-specific DNA binding protein 2, 48kDa -2.62927
GRPEL1 GrpE-like 1, mitochondrial (E. coli) -2.60531
KRT14 keratin 14, type I -2.55321
CTSV cathepsin V -2.54829
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.3849
UBE3C ubiquitin protein ligase E3C -2.31151
KIAA0232 KIAA0232 -2.29433
STXBP1 syntaxin binding protein 1 -2.27098
CREB1 cAMP responsive element binding protein 1 -2.22303
MTERF3 mitochondrial transcription termination factor 3 -2.22006
RCOR1 REST corepressor 1 -2.1738
UFM1 ubiquitin-fold modifier 1 -2.08971
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -2.08553
ZBED2 zinc finger, BED-type containing 2 -2.06199
DSG2 desmoglein 2 -2.02846
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.02377
YME1L1 YME1-like 1 ATPase -2.00927
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -2.00715
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.00172