CRCGN016_MCF10A.TP53.M_24H:E21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description clotrimazole 10.98 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

506 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 9.21083
TXNRD1 thioredoxin reductase 1 8.80302
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 8.69946
HMOX1 heme oxygenase 1 8.09199
AARS1 alanyl-tRNA synthetase 1 7.62517
PYCR1 pyrroline-5-carboxylate reductase 1 6.80652
GLRX glutaredoxin (thioltransferase) 6.69501
CTSL cathepsin L 6.40913
PSAT1 phosphoserine aminotransferase 1 6.32902
PHGDH phosphoglycerate dehydrogenase 6.19884
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 6.10369
XPOT exportin, tRNA 5.89136
GFPT1 glutamine--fructose-6-phosphate transaminase 1 5.77389
ASNS asparagine synthetase (glutamine-hydrolyzing) 5.71501
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 5.63867
TRIB3 tribbles pseudokinase 3 5.61628
GARS1 glycyl-tRNA synthetase 1 5.43167
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 5.42853
ALAS1 5'-aminolevulinate synthase 1 5.30242
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 5.17481
SQSTM1 sequestosome 1 5.07486
RBKS ribokinase 4.90953
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 4.7649
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.66872
GAA glucosidase, alpha; acid 4.60794
ABHD4 abhydrolase domain containing 4 4.43704
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 4.34473
YARS1 tyrosyl-tRNA synthetase 1 4.30329
CARS1 cysteinyl-tRNA synthetase 1 4.1915
LOC128125814 uncharacterized LOC128125814 4.08595
CXCL2 chemokine (C-X-C motif) ligand 2 4.07632
SSBP2 single-stranded DNA binding protein 2 4.05365
VSIG2 V-set and immunoglobulin domain containing 2 4.04567
ECH1 enoyl CoA hydratase 1, peroxisomal 4.01725
ATF4 activating transcription factor 4 3.97031
PRAF2 PRA1 domain family, member 2 3.93497
DDIT4 DNA-damage-inducible transcript 4 3.86772
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 3.84088
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.78166
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.7795
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.7632
HBA1 hemoglobin, alpha 1 3.72458
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 3.59086
LRP10 low density lipoprotein receptor-related protein 10 3.57674
NARS1 asparaginyl-tRNA synthetase 1 3.56968
TARS1 threonyl-tRNA synthetase 1 3.56101
GTPBP2 GTP binding protein 2 3.52862
TWF2 twinfilin actin binding protein 2 3.52469
CCDC92 coiled-coil domain containing 92 3.52384
FYN FYN proto-oncogene, Src family tyrosine kinase 3.50433
NUCB2 nucleobindin 2 3.49779
GRB10 growth factor receptor-bound protein 10 3.47735
C2CD2 C2 calcium-dependent domain containing 2 3.46265
WARS1 tryptophanyl-tRNA synthetase 1 3.43524
CCNA1 cyclin A1 3.43212
NLRP4 NLR family, pyrin domain containing 4 3.41998
SARS1 seryl-tRNA synthetase 1 3.4149
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 3.39232
IL1B interleukin 1, beta 3.34455
TERF2IP telomeric repeat binding factor 2, interacting protein 3.33954
MARS1 methionyl-tRNA synthetase 1 3.33948
PPARG peroxisome proliferator-activated receptor gamma 3.30572
EGR1 early growth response 1 3.29646
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 3.27996
STC2 stanniocalcin 2 3.24466
IARS1 isoleucyl-tRNA synthetase 1 3.24157
HAX1 HCLS1 associated protein X-1 3.2229
LOC102724560 cystathionine beta-synthase 3.21611
ACAA1 acetyl-CoA acyltransferase 1 3.20619
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 3.17748
CDPF1 cysteine-rich, DPF motif domain containing 1 3.129
ABHD6 abhydrolase domain containing 6 3.12768
UGDH UDP-glucose 6-dehydrogenase 3.10753
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 3.06792
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 2.98911
SLC67A1 solute carrier family 67 member 1 2.98899
TCTN1 tectonic family member 1 2.92806
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.90632
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.90261
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 2.85791
HMBOX1 homeobox containing 1 2.84051
MAP7 microtubule-associated protein 7 2.79417
FNDC4 fibronectin type III domain containing 4 2.788
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 2.77776
SOCS2 suppressor of cytokine signaling 2 2.77646
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.77053
ACTMAP actin maturation protease 2.71259
SPG11 spastic paraplegia 11 (autosomal recessive) 2.70851
TES testin LIM domain protein 2.70721
IER3 immediate early response 3 2.70163
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.69397
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.68524
TXLNA taxilin alpha 2.68188
ACSS3 acyl-CoA synthetase short-chain family member 3 2.68008
GSTZ1 glutathione S-transferase zeta 1 2.67479
G0S2 G0/G1 switch 2 2.66723
EPRS1 glutamyl-prolyl-tRNA synthetase 1 2.65445
SIL1 SIL1 nucleotide exchange factor 2.63882
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.61988
AKTIP AKT interacting protein 2.61049
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.55743
SLC35B1 solute carrier family 35, member B1 2.55712
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.54627
HMGA2 high mobility group AT-hook 2 2.52253
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 2.50841
S100P S100 calcium binding protein P 2.50801
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.5071
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.49053
IFT88 intraflagellar transport 88 2.47374
IFRD1 interferon-related developmental regulator 1 2.46025
GOLT1A golgi transport 1A 2.44735
ORAI3 ORAI calcium release-activated calcium modulator 3 2.44675
WFS1 Wolfram syndrome 1 (wolframin) 2.44599
GALE UDP-galactose-4-epimerase 2.44506
NFE2L1 nuclear factor, erythroid 2-like 1 2.43083
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough 2.38551
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.37864
ACY1 aminoacylase 1 2.3612
NRDC nardilysin convertase 2.31095
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 2.28885
MSRA methionine sulfoxide reductase A 2.28851
PCCB propionyl CoA carboxylase, beta polypeptide 2.2873
ACADVL acyl-CoA dehydrogenase, very long chain 2.27917
ZCCHC8 zinc finger, CCHC domain containing 8 2.27602
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.2742
STAMBP STAM binding protein 2.27273
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 2.26149
NAMPT nicotinamide phosphoribosyltransferase 2.25804
CERS2 ceramide synthase 2 2.25784
CHIC2 cysteine-rich hydrophobic domain 2 2.25584
BAX BCL2-associated X protein 2.2493
METTL25B methyltransferase like 25B 2.24151
NCK2 NCK adaptor protein 2 2.23781
IGHMBP2 immunoglobulin mu binding protein 2 2.23382
NPIPB5 nuclear pore complex interacting protein family, member B5 2.21542
ITM2A integral membrane protein 2A 2.21513
NIT1 nitrilase 1 2.21235
KRCC1 lysine-rich coiled-coil 1 2.20777
ACTC1 actin, alpha, cardiac muscle 1 2.20423
GDF5 growth differentiation factor 5 2.19539
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.194
SRPK3 SRSF protein kinase 3 2.18823
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.18102
NUPR1 nuclear protein, transcriptional regulator, 1 2.17183
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.16999
SSR4 signal sequence receptor, delta 2.16247
CHMP4B charged multivesicular body protein 4B 2.15865
KMT5B lysine methyltransferase 5B 2.15802
ERP29 endoplasmic reticulum protein 29 2.15047
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2.14875
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.14082
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.13723
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.13153
AGTPBP1 ATP/GTP binding protein 1 2.12506
TSKU tsukushi, small leucine rich proteoglycan 2.1185
SETD5 SET domain containing 5 2.11646
ANKRD11 ankyrin repeat domain 11 2.11106
INHBE inhibin, beta E 2.1068
P4HB prolyl 4-hydroxylase, beta polypeptide 2.10229
TALDO1 transaldolase 1 2.09406
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 2.0863
LOC114841035 uncharacterized LOC114841035 2.08379
PLIN2 perilipin 2 2.08185
INPP1 inositol polyphosphate-1-phosphatase 2.08064
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 2.0791
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.07184
WIF1 WNT inhibitory factor 1 2.06982
ZCWPW1 zinc finger, CW type with PWWP domain 1 2.0692
EBI3 Epstein-Barr virus induced 3 2.066
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 2.06565
GOLGA8N golgin A8 family, member N 2.06498
OSBPL9 oxysterol binding protein-like 9 2.06188
BAMBI BMP and activin membrane-bound inhibitor 2.0605
ATF3 activating transcription factor 3 2.06023
CAMTA2 calmodulin binding transcription activator 2 2.05842
HDLBP high density lipoprotein binding protein 2.05639
HBEGF heparin-binding EGF-like growth factor 2.05597
FDXR ferredoxin reductase 2.04565
IL1A interleukin 1, alpha 2.0447
MYH9 myosin, heavy chain 9, non-muscle 2.03243
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.02953
TM9SF3 transmembrane 9 superfamily member 3 2.02704
GMPPA GDP-mannose pyrophosphorylase A 2.0245
WDR19 WD repeat domain 19 2.02177
P3H1 prolyl 3-hydroxylase 1 2.02102
RNF103 ring finger protein 103 2.01583
GK glycerol kinase 2.01554
RAB21 RAB21, member RAS oncogene family 2.01303
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.01094
UNC13D unc-13 homolog D (C. elegans) 2.0011

decreased expression

Symbol Name Standardized Value
DCK deoxycytidine kinase -7.85606
PCNA proliferating cell nuclear antigen -7.106
ADRB2 adrenoceptor beta 2, surface -5.949
STMN1 stathmin 1 -5.65328
PRR15L proline rich 15-like -5.3587
CDC45 cell division cycle 45 -4.98323
TUBB6 tubulin, beta 6 class V -4.9596
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.81861
MCM3 minichromosome maintenance complex component 3 -4.47303
PSRC1 proline/serine-rich coiled-coil 1 -4.39762
HOXA5 homeobox A5 -4.24785
NUP85 nucleoporin 85kDa -4.22966
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.07955
HSPA8 heat shock 70kDa protein 8 -3.99456
SMNDC1 survival motor neuron domain containing 1 -3.9251
CDC20 cell division cycle 20 -3.92249
RFC2 replication factor C (activator 1) 2, 40kDa -3.88892
GINS3 GINS complex subunit 3 (Psf3 homolog) -3.88381
GOLT1B golgi transport 1B -3.8309
ISOC1 isochorismatase domain containing 1 -3.72808
FEN1 flap structure-specific endonuclease 1 -3.68645
GMNN geminin, DNA replication inhibitor -3.56419
RECQL RecQ helicase-like -3.52007
GRWD1 glutamate-rich WD repeat containing 1 -3.51068
BIRC5 baculoviral IAP repeat containing 5 -3.46199
MSH2 mutS homolog 2 -3.42911
GADD45B growth arrest and DNA-damage-inducible, beta -3.40354
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -3.37214
CDK1 cyclin-dependent kinase 1 -3.25843
LINS1 lines homolog 1 -3.24788
SPC25 SPC25, NDC80 kinetochore complex component -3.24482
DSN1 DSN1, MIS12 kinetochore complex component -3.24426
ERCC6L excision repair cross-complementation group 6-like -3.2442
GTF2A2 general transcription factor IIA, 2, 12kDa -3.18044
RAD51AP1 RAD51 associated protein 1 -3.17116
SRSF2 serine/arginine-rich splicing factor 2 -3.16218
CORO1A coronin, actin binding protein, 1A -3.1531
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.13763
PLSCR1 phospholipid scramblase 1 -3.1297
BAG3 BCL2-associated athanogene 3 -3.12129
TMEM51 transmembrane protein 51 -3.11203
RBL1 retinoblastoma-like 1 -3.05471
RFC3 replication factor C (activator 1) 3, 38kDa -3.04852
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.03611
CYCS cytochrome c, somatic -3.02464
GPR88 G protein-coupled receptor 88 -2.96184
CDC6 cell division cycle 6 -2.95227
TK1 thymidine kinase 1, soluble -2.92872
HOXC4 homeobox C4 -2.90243
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -2.9006
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.89789
EMP2 epithelial membrane protein 2 -2.89258
ASF1B anti-silencing function 1B histone chaperone -2.87319
SPON1 spondin 1, extracellular matrix protein -2.85994
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.85789
MED21 mediator complex subunit 21 -2.85368
HSPB1 heat shock 27kDa protein 1 -2.85289
MEIS2 Meis homeobox 2 -2.83476
MCM10 minichromosome maintenance complex component 10 -2.83156
CENPI centromere protein I -2.82345
KIF20A kinesin family member 20A -2.81127
CCNF cyclin F -2.81003
HOXA4 homeobox A4 -2.79307
LINC02762 long intergenic non-protein coding RNA 2762 -2.78849
NUSAP1 nucleolar and spindle associated protein 1 -2.78639
GPR6 G protein-coupled receptor 6 -2.78529
DBR1 debranching RNA lariats 1 -2.78251
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.78011
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.77795
ZDHHC6 zinc finger, DHHC-type containing 6 -2.77478
STIL SCL/TAL1 interrupting locus -2.77181
TCF21 transcription factor 21 -2.76583
NLRP2B NLR family pyrin domain containing 2B -2.76324
ARHGAP11A Rho GTPase activating protein 11A -2.74349
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.73888
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -2.73624
CCNB1 cyclin B1 -2.72489
SMC4 structural maintenance of chromosomes 4 -2.72344
KIF18B kinesin family member 18B -2.71857
TCEA2 transcription elongation factor A (SII), 2 -2.70922
MCM7 minichromosome maintenance complex component 7 -2.68943
BRCA1 breast cancer 1, early onset -2.68436
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -2.68245
ABHD11 abhydrolase domain containing 11 -2.67557
NDC1 NDC1 transmembrane nucleoporin -2.66902
MICA MHC class I polypeptide-related sequence A -2.66311
PARP2 poly (ADP-ribose) polymerase 2 -2.65505
ZNF557 zinc finger protein 557 -2.65249
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.65013
ZNF318 zinc finger protein 318 -2.63949
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.62632
CCNB2 cyclin B2 -2.61788
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.60403
VANGL1 VANGL planar cell polarity protein 1 -2.59843
KIF4A kinesin family member 4A -2.5922
PYDC1 PYD (pyrin domain) containing 1 -2.58762
SST somatostatin -2.58753
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.58136
RTP4 receptor (chemosensory) transporter protein 4 -2.5745
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -2.57184
SRSF3 serine/arginine-rich splicing factor 3 -2.57031
CCNA2 cyclin A2 -2.55838
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.54984
FANCG Fanconi anemia, complementation group G -2.54703
HAT1 histone acetyltransferase 1 -2.54223
PGAM4 phosphoglycerate mutase family member 4 -2.53531
ANXA11 annexin A11 -2.53173
MCM5 minichromosome maintenance complex component 5 -2.52438
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.5179
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.51455
DSCC1 DNA replication and sister chromatid cohesion 1 -2.50564
ELOVL6 ELOVL fatty acid elongase 6 -2.50333
MUC16 mucin 16, cell surface associated -2.50213
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.50091
PHTF2 putative homeodomain transcription factor 2 -2.49568
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.49338
ZNF207 zinc finger protein 207 -2.49262
CPNE3 copine III -2.49227
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.49077
QSER1 glutamine and serine rich 1 -2.48958
CENPQ centromere protein Q -2.4874
CRYZ crystallin, zeta (quinone reductase) -2.48072
KIF18A kinesin family member 18A -2.47924
CDK2 cyclin-dependent kinase 2 -2.47085
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.45933
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -2.44954
PPY pancreatic polypeptide -2.44192
GTPBP8 GTP-binding protein 8 (putative) -2.4398
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.43839
TMPO thymopoietin -2.43546
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.4273
NDC80 NDC80 kinetochore complex component -2.42281
CRIPT cysteine-rich PDZ-binding protein -2.4206
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -2.41945
LGALS9C lectin, galactoside-binding, soluble, 9C -2.41251
NCAPD3 non-SMC condensin II complex, subunit D3 -2.41078
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.40856
NOTCH1 notch 1 -2.40293
SAMHD1 SAM domain and HD domain 1 -2.4022
KIF11 kinesin family member 11 -2.40037
SYNJ2BP synaptojanin 2 binding protein -2.4001
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.39587
NUBP2 nucleotide binding protein 2 -2.39401
TRNAU1AP tRNA selenocysteine 1 associated protein 1 -2.39358
MCM6 minichromosome maintenance complex component 6 -2.39356
PNLIP pancreatic lipase -2.39095
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.3872
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.38427
PLK1 polo-like kinase 1 -2.38225
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.37521
SOCS5 suppressor of cytokine signaling 5 -2.37418
FBXO3 F-box protein 3 -2.37091
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 -2.37041
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -2.3678
NUP160 nucleoporin 160kDa -2.36499
TRIP13 thyroid hormone receptor interactor 13 -2.3642
ENC1 ectodermal-neural cortex 1 (with BTB domain) -2.35647
SCN7A sodium channel, voltage gated, type VII alpha subunit -2.3549
IFI44 interferon-induced protein 44 -2.35164
DEPDC1 DEP domain containing 1 -2.34902
SMAD9 SMAD family member 9 -2.34706
NCS1 neuronal calcium sensor 1 -2.34548
CENPN centromere protein N -2.33531
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 -2.332
CPA1 carboxypeptidase A1 (pancreatic) -2.32707
ATRIP ATR interacting protein -2.32288
GCG glucagon -2.32173
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.31856
ITGB8 integrin, beta 8 -2.31743
OAT ornithine aminotransferase -2.31625
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -2.31374
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like -2.30907
WBP11 WW domain binding protein 11 -2.30327
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.30044
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.29663
NASP nuclear autoantigenic sperm protein (histone-binding) -2.29013
JPT2 Jupiter microtubule associated homolog 2 -2.28758
ZNF274 zinc finger protein 274 -2.28451
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -2.28363
ATAD2 ATPase family, AAA domain containing 2 -2.28269
AURKA aurora kinase A -2.28188
ZWINT ZW10 interacting kinetochore protein -2.27997
WNT7B wingless-type MMTV integration site family, member 7B -2.27806
FERRY3 FERRY endosomal RAB5 effector complex subunit 3 -2.27577
BCL7C B-cell CLL/lymphoma 7C -2.26888
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) -2.2657
SAP30L SAP30-like -2.26248
DCTPP1 dCTP pyrophosphatase 1 -2.26019
MIS18BP1 MIS18 binding protein 1 -2.24626
ZMYM1 zinc finger, MYM-type 1 -2.24061
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.23939
FOXM1 forkhead box M1 -2.23408
MCM4 minichromosome maintenance complex component 4 -2.23209
COA3 cytochrome c oxidase assembly factor 3 -2.22961
WDR77 WD repeat domain 77 -2.22947
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.22243
CACNB3 calcium channel, voltage-dependent, beta 3 subunit -2.21805
SRD5A3 steroid 5 alpha-reductase 3 -2.21562
TMEM14A transmembrane protein 14A -2.21331
KPNA5 karyopherin alpha 5 (importin alpha 6) -2.21122
SMIM41 small integral membrane protein 41 -2.21109
HSPA1A heat shock 70kDa protein 1A -2.20513
PNLIPRP2 pancreatic lipase-related protein 2 -2.20318
ATG5 autophagy related 5 -2.20208
NCAPH non-SMC condensin I complex, subunit H -2.19771
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.19726
IAPP islet amyloid polypeptide -2.19723
PRPF38B pre-mRNA processing factor 38B -2.1966
KCTD12 potassium channel tetramerization domain containing 12 -2.19547
RRM2 ribonucleotide reductase M2 -2.1943
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.1937
ANAPC15 anaphase promoting complex subunit 15 -2.19344
EXOSC9 exosome component 9 -2.19326
SLC44A4 solute carrier family 44, member 4 -2.19285
RGS9BP regulator of G protein signaling 9 binding protein -2.19269
CENPM centromere protein M -2.19219
PARPBP PARP1 binding protein -2.19195
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -2.19132
GABPA GA binding protein transcription factor, alpha subunit 60kDa -2.18859
CDC7 cell division cycle 7 -2.18778
DUT deoxyuridine triphosphatase -2.18745
PARP1 poly (ADP-ribose) polymerase 1 -2.18429
RAD54B RAD54 homolog B (S. cerevisiae) -2.17986
GPALPP1 GPALPP motifs containing 1 -2.17918
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.17671
MIS18A MIS18 kinetochore protein A -2.17328
MTAP methylthioadenosine phosphorylase -2.17231
MORC3 MORC family CW-type zinc finger 3 -2.17072
NRTN neurturin -2.16609
MCMBP minichromosome maintenance complex binding protein -2.15565
CENPX centromere protein X -2.15224
LPAR6 lysophosphatidic acid receptor 6 -2.15205
ZNF813 zinc finger protein 813 -2.1509
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.1481
SYNJ1 synaptojanin 1 -2.14766
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.14508
RPP30 ribonuclease P/MRP 30kDa subunit -2.14499
PRIM2 primase, DNA, polypeptide 2 (58kDa) -2.14053
KLK8 kallikrein-related peptidase 8 -2.1387
BZW2 basic leucine zipper and W2 domains 2 -2.13686
ARHGAP15 Rho GTPase activating protein 15 -2.13684
ASRGL1 asparaginase like 1 -2.13639
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -2.13603
PCNT pericentrin -2.1325
UFD1 ubiquitin recognition factor in ER associated degradation 1 -2.12674
TMEM160 transmembrane protein 160 -2.12595
SNIP1 Smad nuclear interacting protein 1 -2.12364
CLN3 ceroid-lipofuscinosis, neuronal 3 -2.12175
TMSB10 thymosin beta 10 -2.1101
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa -2.09721
KITLG KIT ligand -2.09573
TBC1D10C TBC1 domain family, member 10C -2.09441
ZNF675 zinc finger protein 675 -2.09354
LRP3 low density lipoprotein receptor-related protein 3 -2.09327
ST14 suppression of tumorigenicity 14 (colon carcinoma) -2.09124
DBF4 DBF4 zinc finger -2.08636
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -2.08589
TICAM1 toll-like receptor adaptor molecule 1 -2.08327
OSTM1 osteopetrosis associated transmembrane protein 1 -2.08279
MAP3K6 mitogen-activated protein kinase kinase kinase 6 -2.07928
RGS19 regulator of G-protein signaling 19 -2.07463
PRMT7 protein arginine methyltransferase 7 -2.07439
ZDHHC13 zinc finger, DHHC-type containing 13 -2.07397
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.07199
CD320 CD320 molecule -2.07062
RNF111 ring finger protein 111 -2.06961
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.06759
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -2.06643
CBR3 carbonyl reductase 3 -2.06604
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -2.06597
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -2.06328
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.06231
SNCG synuclein, gamma (breast cancer-specific protein 1) -2.0613
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.06103
MED17 mediator complex subunit 17 -2.05888
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -2.05882
MTA2 metastasis associated 1 family, member 2 -2.05704
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.05408
MRPL44 mitochondrial ribosomal protein L44 -2.05103
RACGAP1 Rac GTPase activating protein 1 -2.04942
NAGA N-acetylgalactosaminidase, alpha- -2.04927
CCDC134 coiled-coil domain containing 134 -2.04715
LRRC40 leucine rich repeat containing 40 -2.04498
FGD2 FYVE, RhoGEF and PH domain containing 2 -2.04335
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.04294
EGLN1 egl-9 family hypoxia-inducible factor 1 -2.04283
CDC25A cell division cycle 25A -2.04163
WRAP53 WD repeat containing, antisense to TP53 -2.04109
RBM12 RNA binding motif protein 12 -2.03851
WDR76 WD repeat domain 76 -2.03573
CTRB1 chymotrypsinogen B1 -2.03484
EXO1 exonuclease 1 -2.03337
PDCL phosducin-like -2.03232
HDAC2 histone deacetylase 2 -2.03073
RINT1 RAD50 interactor 1 -2.03014
NUP93 nucleoporin 93kDa -2.0292
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.02901
TIMCC TIM double twin CX3C motif chaperone -2.02813
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -2.02244
TEDC2 tubulin epsilon and delta complex 2 -2.02201
CD4 CD4 molecule -2.01854
NR3C2 nuclear receptor subfamily 3, group C, member 2 -2.01592
SLFN12 schlafen family member 12 -2.01515
NXN nucleoredoxin -2.01489
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.01425
CLEC16A C-type lectin domain family 16, member A -2.01387
UBE2C ubiquitin-conjugating enzyme E2C -2.01369
VRK1 vaccinia related kinase 1 -2.01362
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.01098
CTRL chymotrypsin-like -2.01028
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.01013
BCAP29 B-cell receptor-associated protein 29 -2.00761
VAV3 vav 3 guanine nucleotide exchange factor -2.0055
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.0047
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.0025
SNU13 small nuclear ribonucleoprotein 13 -2.00157