CRCGN016_MCF10A.TP53.M_24H:E23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o,o-dimethyl s-[(4-oxo-1,2,3-benzotriazin-3(4h)-yl)methyl] dithiophosphate 33.95 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

33 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 3.70234
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.43637
ABHD6 abhydrolase domain containing 6 3.16035
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.15593
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.79131
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.66259
COMP cartilage oligomeric matrix protein 2.54822
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.43241
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.37044
MAP7 microtubule-associated protein 7 2.30026
INS insulin 2.09043
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 2.0515
TOMM34 translocase of outer mitochondrial membrane 34 2.00948

decreased expression

Symbol Name Standardized Value
HOXA5 homeobox A5 -5.11868
PCNA proliferating cell nuclear antigen -4.51506
CCDC86 coiled-coil domain containing 86 -3.94416
ANKRD10 ankyrin repeat domain 10 -3.7866
OXA1L oxidase (cytochrome c) assembly 1-like -3.63943
NPDC1 neural proliferation, differentiation and control, 1 -2.92147
HAT1 histone acetyltransferase 1 -2.87626
STX1A syntaxin 1A (brain) -2.79014
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.75168
CCNB1 cyclin B1 -2.63866
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -2.52176
NRIP1 nuclear receptor interacting protein 1 -2.51246
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.41804
TCEA2 transcription elongation factor A (SII), 2 -2.31605
TMEM230 transmembrane protein 230 -2.29791
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.24056
PANK2 pantothenate kinase 2 -2.19453
DHRS3 dehydrogenase/reductase (SDR family) member 3 -2.10188
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.06072
MTERF3 mitochondrial transcription termination factor 3 -2.0069