CRCGN016_MCF10A.TP53.M_24H:E24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o,o-dimethyl s-[(4-oxo-1,2,3-benzotriazin-3(4h)-yl)methyl] dithiophosphate 11.32 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:E24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CNRIP1 cannabinoid receptor interacting protein 1 4.1001
CORO1A coronin, actin binding protein, 1A 3.93931
ZNF586 zinc finger protein 586 3.57683
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.3723
MAP7 microtubule-associated protein 7 3.16984
ZNF587B zinc finger protein 587B 2.70508
COQ8A coenzyme Q8A 2.66322
PRKX protein kinase, X-linked 2.52584
NUP133 nucleoporin 133kDa 2.22811
TBC1D31 TBC1 domain family, member 31 2.07201

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.2351
STX1A syntaxin 1A (brain) -4.08677
TNIP1 TNFAIP3 interacting protein 1 -3.79553
RNF167 ring finger protein 167 -3.65332
HSPA1A heat shock 70kDa protein 1A -3.16965
DCK deoxycytidine kinase -2.80778
IPO13 importin 13 -2.54091
REXO2 RNA exonuclease 2 -2.48581
HOXA5 homeobox A5 -2.37937
CAB39 calcium binding protein 39 -2.37709
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.25574
IFRD2 interferon-related developmental regulator 2 -2.20671
RAB3A RAB3A, member RAS oncogene family -2.0646
TPRA1 transmembrane protein, adipocyte asscociated 1 -2.00189
TMEM115 transmembrane protein 115 -2.00136