CRCGN016_MCF10A.TP53.M_24H:F01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hc blue no. 2 100.97 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCDC92 coiled-coil domain containing 92 3.94429
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 3.12896
ABHD6 abhydrolase domain containing 6 3.12
PMM2 phosphomannomutase 2 2.50948
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.185
RAB21 RAB21, member RAS oncogene family 2.1218
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.10926
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.0816
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.02252

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -4.86789
KIF14 kinesin family member 14 -3.41073
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.17974
RPIA ribose 5-phosphate isomerase A -3.11566
TEX10 testis expressed 10 -2.72139
NLRP4 NLR family, pyrin domain containing 4 -2.64285
SORBS3 sorbin and SH3 domain containing 3 -2.11666
IQGAP1 IQ motif containing GTPase activating protein 1 -2.08139
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.04075
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -2.03445