CRCGN016_MCF10A.TP53.M_24H:F02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hc blue no. 2 33.66 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 3.85812
HMOX1 heme oxygenase 1 2.79697
ACAA1 acetyl-CoA acyltransferase 1 2.74504
SATB1 SATB homeobox 1 2.55499
HBA1 hemoglobin, alpha 1 2.49008
ADAM10 ADAM metallopeptidase domain 10 2.4295
TLR4 toll-like receptor 4 2.34538
RPL39L ribosomal protein L39-like 2.09398
MYO5A myosin VA (heavy chain 12, myoxin) 2.09093
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 2.04756
TMEM39B transmembrane protein 39B 2.03893
TLN1 talin 1 2.02343
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.01312

decreased expression

Symbol Name Standardized Value
UBE3C ubiquitin protein ligase E3C -5.13746
CCNB1 cyclin B1 -4.80924
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.40278
KIF14 kinesin family member 14 -2.44712
OXA1L oxidase (cytochrome c) assembly 1-like -2.33166
GRN granulin -2.20494
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.17929
CAPN2 calpain 2, (m/II) large subunit -2.11372
XPO7 exportin 7 -2.08218
TENT2 terminal nucleotidyltransferase 2 -2.08077
USP6 ubiquitin specific peptidase 6 -2.03492