CRCGN016_MCF10A.TP53.M_24H:F03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hc blue no. 2 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHEK1 checkpoint kinase 1 2.72952
ZMIZ1 zinc finger, MIZ-type containing 1 2.41525
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.15486
WFS1 Wolfram syndrome 1 (wolframin) 2.15286
MCUR1 mitochondrial calcium uniporter regulator 1 2.11805

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -6.98294
PCCB propionyl CoA carboxylase, beta polypeptide -4.51894
NPDC1 neural proliferation, differentiation and control, 1 -3.96389
NRIP1 nuclear receptor interacting protein 1 -3.72856
SNCA synuclein, alpha (non A4 component of amyloid precursor) -3.31584
ACOT9 acyl-CoA thioesterase 9 -3.14847
PLK1 polo-like kinase 1 -2.95032
KRT14 keratin 14, type I -2.37809
TSPAN3 tetraspanin 3 -2.37729