| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | nitrosoethylmethylamine 11.05 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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103 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 | 5.04624 |
| HBA1 | hemoglobin, alpha 1 | 3.83603 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 3.75478 |
| TBX2 | T-box 2 | 3.75063 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.58766 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.32906 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.03872 |
| EPHB2 | EPH receptor B2 | 2.98575 |
| VRK2 | vaccinia related kinase 2 | 2.79238 |
| TLCD3A | TLC domain containing 3A | 2.74208 |
| KPTN | kaptin (actin binding protein) | 2.64798 |
| EVL | Enah/Vasp-like | 2.62637 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 2.6164 |
| CD19 | CD19 molecule | 2.51737 |
| HBB | hemoglobin, beta | 2.51123 |
| ZBED5 | zinc finger, BED-type containing 5 | 2.46642 |
| TMEM50B | transmembrane protein 50B | 2.41246 |
| MAGEC1 | melanoma antigen family C1 | 2.39702 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 2.38079 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | 2.37385 |
| TYW2 | tRNA wybutosine-synthesizing protein 2 | 2.3462 |
| RPAIN | RPA interacting protein | 2.34098 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 2.34069 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.32176 |
| IL24 | interleukin 24 | 2.31488 |
| CCN6 | cellular communication network factor 6 | 2.31294 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 2.2601 |
| MAGEA6 | melanoma antigen family A6 | 2.2397 |
| LOC100533997 | MAGEA10-MAGEA5 readthrough | 2.22053 |
| GMPS | guanine monphosphate synthase | 2.21252 |
| OLFML2B | olfactomedin-like 2B | 2.21035 |
| RBMY1J | RNA binding motif protein, Y-linked, family 1, member J | 2.19552 |
| COMP | cartilage oligomeric matrix protein | 2.15544 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | 2.15524 |
| CADM1 | cell adhesion molecule 1 | 2.15282 |
| PEX6 | peroxisomal biogenesis factor 6 | 2.14742 |
| TTC26 | tetratricopeptide repeat domain 26 | 2.1426 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 2.14114 |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 | 2.12982 |
| VPREB1 | pre-B lymphocyte 1 | 2.12828 |
| NXF2B | nuclear RNA export factor 2B | 2.08705 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | 2.08358 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.0783 |
| CCDC81 | coiled-coil domain containing 81 | 2.07586 |
| ZFHX3 | zinc finger homeobox 3 | 2.06688 |
| SMAD3 | SMAD family member 3 | 2.0643 |
| MAGEA10 | melanoma antigen family A10 | 2.05377 |
| MTA2 | metastasis associated 1 family, member 2 | 2.04877 |
| WDR4 | WD repeat domain 4 | 2.03414 |
| LOXL1 | lysyl oxidase-like 1 | 2.01912 |
| CST2 | cystatin SA | 2.01581 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 2.0119 |
| SMC6 | structural maintenance of chromosomes 6 | 2.01072 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 2.0106 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 2.01013 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 | 2.00301 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 2.00023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KIF14 | kinesin family member 14 | -10.0 |
| SLC35B1 | solute carrier family 35, member B1 | -8.67296 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -5.95709 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -4.92809 |
| ENOPH1 | enolase-phosphatase 1 | -4.84155 |
| UFM1 | ubiquitin-fold modifier 1 | -4.43605 |
| KAT7 | K(lysine) acetyltransferase 7 | -3.32091 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -3.26694 |
| COTL1 | coactosin-like F-actin binding protein 1 | -3.04695 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -2.99031 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 | -2.93361 |
| ATG3 | autophagy related 3 | -2.7738 |
| TEX10 | testis expressed 10 | -2.74129 |
| PROSER1 | proline and serine rich 1 | -2.66396 |
| SLC35A5 | solute carrier family 35, member A5 | -2.64238 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | -2.63728 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | -2.63321 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit | -2.55967 |
| LRRC59 | leucine rich repeat containing 59 | -2.55237 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | -2.49574 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) | -2.46225 |
| TMEM176B | transmembrane protein 176B | -2.39297 |
| KCTD3 | potassium channel tetramerization domain containing 3 | -2.33731 |
| EXOSC8 | exosome component 8 | -2.31829 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.28035 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -2.25986 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa | -2.24129 |
| POMP | proteasome maturation protein | -2.23381 |
| RPS5 | ribosomal protein S5 | -2.22573 |
| PHB1 | prohibitin 1 | -2.17729 |
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | -2.1614 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | -2.12626 |
| SPOP | speckle-type POZ protein | -2.12159 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -2.11638 |
| MGST3 | microsomal glutathione S-transferase 3 | -2.09623 |
| NOP10 | NOP10 ribonucleoprotein | -2.09171 |
| MED4 | mediator complex subunit 4 | -2.0881 |
| OSBPL11 | oxysterol binding protein-like 11 | -2.08403 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -2.07278 |
| TMEM176A | transmembrane protein 176A | -2.06342 |
| DENND1B | DENN/MADD domain containing 1B | -2.04285 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -2.01465 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -2.01004 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -2.00733 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | -2.00425 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 | -2.0042 |
