CRCGN016_MCF10A.TP53.M_24H:F13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description thiram 99.96 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

1027 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CEMIP2 cell migration inducing hyaluronidase 2 10.0
HSPA1A heat shock 70kDa protein 1A 9.69049
HMOX1 heme oxygenase 1 9.5706
TRIB1 tribbles pseudokinase 1 8.76048
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 8.64488
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 8.44534
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 8.21517
EGR1 early growth response 1 8.03926
ALDOC aldolase C, fructose-bisphosphate 7.88694
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 7.88304
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 7.51616
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 7.39957
RNASE7 ribonuclease, RNase A family, 7 7.11585
RGS2 regulator of G-protein signaling 2 6.95429
HSPA1B heat shock 70kDa protein 1B 6.20475
TBPL1 TBP-like 1 6.19852
CXCL2 chemokine (C-X-C motif) ligand 2 6.09467
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 5.705
ALAS1 5'-aminolevulinate synthase 1 5.58466
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 5.49914
PPP1R15A protein phosphatase 1, regulatory subunit 15A 5.39472
TOMM34 translocase of outer mitochondrial membrane 34 5.2299
HSPA6 heat shock 70kDa protein 6 (HSP70B') 5.16672
CADM1 cell adhesion molecule 1 5.08575
TXNL4B thioredoxin-like 4B 5.02334
UGDH UDP-glucose 6-dehydrogenase 4.96597
CHIC2 cysteine-rich hydrophobic domain 2 4.80533
SLC35B1 solute carrier family 35, member B1 4.78078
GADD45B growth arrest and DNA-damage-inducible, beta 4.74913
BDH1 3-hydroxybutyrate dehydrogenase, type 1 4.70967
IER5 immediate early response 5 4.48884
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 4.40688
SQSTM1 sequestosome 1 4.40348
ZFP36 ZFP36 ring finger protein 4.38627
BUD31 BUD31 homolog (S. cerevisiae) 4.3568
ATF3 activating transcription factor 3 4.32347
FOSB FBJ murine osteosarcoma viral oncogene homolog B 4.29961
EDN1 endothelin 1 4.25678
TP53BP2 tumor protein p53 binding protein 2 4.25457
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 4.24206
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 4.2248
IGFBP3 insulin-like growth factor binding protein 3 4.21363
CRELD2 cysteine-rich with EGF-like domains 2 4.18633
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 4.15901
BAG3 BCL2-associated athanogene 3 4.02521
CBR3 carbonyl reductase 3 4.01777
COMP cartilage oligomeric matrix protein 4.01157
RAB21 RAB21, member RAS oncogene family 3.9862
CCL3L3 chemokine (C-C motif) ligand 3-like 3 3.9521
RBM22 RNA binding motif protein 22 3.94418
FHL2 four and a half LIM domains 2 3.93664
JMJD6 jumonji domain containing 6 3.90237
RMC1 regulator of MON1-CCZ1 3.89513
GATA2 GATA binding protein 2 3.88295
HSPA8 heat shock 70kDa protein 8 3.87174
BZW2 basic leucine zipper and W2 domains 2 3.83855
IFRD1 interferon-related developmental regulator 1 3.83072
CTNNBL1 catenin, beta like 1 3.79494
SOX4 SRY (sex determining region Y)-box 4 3.78984
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 3.78903
IRF7 interferon regulatory factor 7 3.76306
RND1 Rho family GTPase 1 3.75407
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 3.7331
FRS2 fibroblast growth factor receptor substrate 2 3.72684
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 3.69968
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 3.67071
GABPB1 GA binding protein transcription factor, beta subunit 1 3.67036
BAMBI BMP and activin membrane-bound inhibitor 3.6654
MMP1 matrix metallopeptidase 1 3.66255
PLA2G15 phospholipase A2, group XV 3.63985
LIN37 lin-37 DREAM MuvB core complex component 3.63953
IL1B interleukin 1, beta 3.62601
CTSL cathepsin L 3.61824
HBA1 hemoglobin, alpha 1 3.61495
NOSIP nitric oxide synthase interacting protein 3.61208
EGR3 early growth response 3 3.60725
IST1 increased sodium tolerance 1 homolog (yeast) 3.60199
GCC1 GRIP and coiled-coil domain containing 1 3.60101
RYBP RING1 and YY1 binding protein 3.57178
LOC128125814 uncharacterized LOC128125814 3.56342
SPAG4 sperm associated antigen 4 3.54973
IL6 interleukin 6 3.52291
HSPA2 heat shock 70kDa protein 2 3.50401
ADRM1 adhesion regulating molecule 1 3.49151
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.48516
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 3.47639
FOS FBJ murine osteosarcoma viral oncogene homolog 3.46634
UBQLN2 ubiquilin 2 3.46151
H2BC12 H2B clustered histone 12 3.45026
CXCL3 chemokine (C-X-C motif) ligand 3 3.43898
RTF2 replication termination factor 2 3.43032
BMP2 bone morphogenetic protein 2 3.41585
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.40276
ZNF586 zinc finger protein 586 3.38962
NUCB2 nucleobindin 2 3.38721
AFF4 AF4/FMR2 family, member 4 3.3673
RLF rearranged L-myc fusion 3.33242
UBE2C ubiquitin-conjugating enzyme E2C 3.3187
CCNL1 cyclin L1 3.29675
NUP93 nucleoporin 93kDa 3.29302
MON1B MON1 secretory trafficking family member B 3.2498
NUDC nudC nuclear distribution protein 3.24691
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 3.24445
CDKN2AIP CDKN2A interacting protein 3.23393
LIF leukemia inhibitory factor 3.23274
CSRP2 cysteine and glycine-rich protein 2 3.20898
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 3.20519
AXIN1 axin 1 3.20169
CCNE2 cyclin E2 3.18322
BTG1 B-cell translocation gene 1, anti-proliferative 3.17034
GOLT1B golgi transport 1B 3.10251
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 3.09747
MMP10 matrix metallopeptidase 10 3.08388
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 3.08241
ZNF473 zinc finger protein 473 3.07426
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 3.06948
IER3 immediate early response 3 3.06414
GARS1 glycyl-tRNA synthetase 1 3.05885
FIP1L1 factor interacting with PAPOLA and CPSF1 3.05102
CXCL8 chemokine (C-X-C motif) ligand 8 3.04189
NPC1 Niemann-Pick disease, type C1 3.03977
FICD FIC domain containing 2.99127
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.97796
ISG20 interferon stimulated exonuclease gene 20kDa 2.97363
GMEB2 glucocorticoid modulatory element binding protein 2 2.97114
WIF1 WNT inhibitory factor 1 2.96479
HSPH1 heat shock 105kDa/110kDa protein 1 2.96099
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.95704
YTHDC1 YTH domain containing 1 2.95397
IL24 interleukin 24 2.9538
TEX10 testis expressed 10 2.94609
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.92751
SDF2L1 stromal cell-derived factor 2-like 1 2.92122
TUBB6 tubulin, beta 6 class V 2.90882
CFAP20 cilia and flagella associated protein 20 2.90336
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.89757
ZNF212 zinc finger protein 212 2.89723
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.89641
CCN2 cellular communication network factor 2 2.89494
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.8942
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.88546
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.8784
HBEGF heparin-binding EGF-like growth factor 2.87186
JUN jun proto-oncogene 2.86895
PELI1 pellino E3 ubiquitin protein ligase 1 2.83695
RRAGC Ras-related GTP binding C 2.83667
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.83532
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.80728
RBM28 RNA binding motif protein 28 2.8039
KIN Kin17 DNA and RNA binding protein 2.80143
MSX2 msh homeobox 2 2.79526
ATG101 autophagy related 101 2.79026
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.79023
CDPF1 cysteine-rich, DPF motif domain containing 1 2.78497
PPY pancreatic polypeptide 2.77812
TIMP2 TIMP metallopeptidase inhibitor 2 2.77366
RALY RALY heterogeneous nuclear ribonucleoprotein 2.76879
MICB MHC class I polypeptide-related sequence B 2.76117
RBM6 RNA binding motif protein 6 2.75592
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 2.75491
ZC3H7A zinc finger CCCH-type containing 7A 2.7413
INHBA inhibin, beta A 2.74094
SART1 squamous cell carcinoma antigen recognized by T cells 2.74023
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.73886
CSRNP2 cysteine-serine-rich nuclear protein 2 2.72278
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.71586
STX5 syntaxin 5 2.69509
SPATA2L spermatogenesis associated 2-like 2.69061
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 2.68991
DERL2 derlin 2 2.68589
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 2.68322
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.6787
FOXJ3 forkhead box J3 2.67059
MCOLN1 mucolipin 1 2.66852
PDLIM1 PDZ and LIM domain 1 2.66534
KLF4 Kruppel-like factor 4 (gut) 2.66507
TUBB2A tubulin, beta 2A class IIa 2.66338
H2BC9 H2B clustered histone 9 2.66205
RGS16 regulator of G-protein signaling 16 2.65848
BMP6 bone morphogenetic protein 6 2.65388
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.6537
WFS1 Wolfram syndrome 1 (wolframin) 2.65158
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.64339
ARID5A AT rich interactive domain 5A (MRF1-like) 2.64189
LOC122526780 uncharacterized LOC122526780 2.63337
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.63233
RBM42 RNA binding motif protein 42 2.62777
FOXD1 forkhead box D1 2.61104
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 2.60962
H2BC4 H2B clustered histone 4 2.60506
PSMC3IP PSMC3 interacting protein 2.60205
ZFPM1 zinc finger protein, FOG family member 1 2.60176
CD83 CD83 molecule 2.59826
MRPL18 mitochondrial ribosomal protein L18 2.59501
JUND jun D proto-oncogene 2.59001
RNF25 ring finger protein 25 2.58801
KDM6B lysine (K)-specific demethylase 6B 2.58451
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 2.58413
TEX14 testis expressed 14 2.5805
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.5786
COL9A2 collagen, type IX, alpha 2 2.57545
SAP30BP SAP30 binding protein 2.57402
SNW1 SNW domain containing 1 2.5701
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.56963
BRD2 bromodomain containing 2 2.56913
IL11 interleukin 11 2.5653
SPHK1 sphingosine kinase 1 2.56446
LGMN legumain 2.56019
COPZ2 coatomer protein complex, subunit zeta 2 2.5557
CCL4 chemokine (C-C motif) ligand 4 2.54827
USB1 U6 snRNA biogenesis 1 2.54767
ARC activity-regulated cytoskeleton-associated protein 2.54066
CCL20 chemokine (C-C motif) ligand 20 2.5389
CIRSR corepressor of RBPJ and splicing regulator 2.53142
KATNA1 katanin p60 (ATPase containing) subunit A 1 2.52952
RHOB ras homolog family member B 2.52267
SDC4 syndecan 4 2.5145
BRMS1L breast cancer metastasis-suppressor 1-like 2.51057
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 2.49799
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 2.49588
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 2.49024
SNIP1 Smad nuclear interacting protein 1 2.47991
BANP BTG3 associated nuclear protein 2.47972
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 2.45736
RFWD3 ring finger and WD repeat domain 3 2.45597
TERF2IP telomeric repeat binding factor 2, interacting protein 2.45511
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 2.44769
HYI hydroxypyruvate isomerase (putative) 2.44662
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 2.44012
SH2D2A SH2 domain containing 2A 2.43605
CHD1 chromodomain helicase DNA binding protein 1 2.43421
ZNF668 zinc finger protein 668 2.43282
ZBTB10 zinc finger and BTB domain containing 10 2.4316
MMP3 matrix metallopeptidase 3 2.43022
IER2 immediate early response 2 2.4302
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.42506
ARID5B AT rich interactive domain 5B (MRF1-like) 2.42489
AEBP1 AE binding protein 1 2.42359
SMIM40 small integral membrane protein 40 2.42311
NUP58 nucleoporin 58 2.41924
ZNF281 zinc finger protein 281 2.4188
PPME1 protein phosphatase methylesterase 1 2.41331
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 2.41218
GPKOW G patch domain and KOW motifs 2.40764
TUFT1 tuftelin 1 2.40652
TDG thymine-DNA glycosylase 2.40568
METTL22 methyltransferase like 22 2.40552
NR4A3 nuclear receptor subfamily 4, group A, member 3 2.40216
MANF mesencephalic astrocyte-derived neurotrophic factor 2.39703
ZNF10 zinc finger protein 10 2.39473
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.3943
GNG5 guanine nucleotide binding protein (G protein), gamma 5 2.38671
LOC102724023 ES1 protein homolog, mitochondrial 2.38616
CRY1 cryptochrome circadian clock 1 2.38123
SMIM29 small integral membrane protein 29 2.37729
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 2.37614
PARP12 poly (ADP-ribose) polymerase family, member 12 2.37425
GADD45A growth arrest and DNA-damage-inducible, alpha 2.37177
ZNF222 zinc finger protein 222 2.37016
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.36217
PLAUR plasminogen activator, urokinase receptor 2.36106
NR4A1 nuclear receptor subfamily 4, group A, member 1 2.35534
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.35115
BCAS2 breast carcinoma amplified sequence 2 2.3503
STK10 serine/threonine kinase 10 2.34779
CAVIN3 caveolae associated protein 3 2.33741
DLX2 distal-less homeobox 2 2.33608
ATF4 activating transcription factor 4 2.33503
VSIG2 V-set and immunoglobulin domain containing 2 2.33414
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.33023
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.32818
TSSC4 tumor suppressing subtransferable candidate 4 2.32349
FASTKD5 FAST kinase domains 5 2.31621
DAPK3 death-associated protein kinase 3 2.31583
NRBF2 nuclear receptor binding factor 2 2.31562
EHD1 EH-domain containing 1 2.31284
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 2.31238
DUSP8 dual specificity phosphatase 8 2.30918
BTG2 BTG family, member 2 2.30356
RAB8B RAB8B, member RAS oncogene family 2.29794
RBMX2 RNA binding motif protein, X-linked 2 2.29649
OXSR1 oxidative stress responsive 1 2.29613
GJD3 gap junction protein, delta 3, 31.9kDa 2.29129
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.28977
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 2.28642
DUSP5 dual specificity phosphatase 5 2.28549
CCDC59 coiled-coil domain containing 59 2.28544
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 2.28423
C6ORF89 chromosome 6 open reading frame 89 2.28147
LOC127933115 uncharacterized LOC127933115 2.27346
KLHL7 kelch-like family member 7 2.27195
GPR137B G protein-coupled receptor 137B 2.26861
FAM53C family with sequence similarity 53, member C 2.25716
SFMBT1 Scm-like with four mbt domains 1 2.25587
CLIP3 CAP-GLY domain containing linker protein 3 2.25586
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.24885
LSG1 large 60S subunit nuclear export GTPase 1 2.24751
TBX2 T-box 2 2.24445
SPATA2 spermatogenesis associated 2 2.24239
COCH cochlin 2.24161
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 2.23671
LOC102724594 splicing factor U2AF 35 kDa subunit 2.23188
AP4M1 adaptor-related protein complex 4, mu 1 subunit 2.22435
TCP1 t-complex 1 2.21964
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.21401
CD72 CD72 molecule 2.21374
H1-2 H1.2 linker histone, cluster member 2.21133
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.21014
MACO1 macoilin 1 2.20614
RAB30 RAB30, member RAS oncogene family 2.20097
CDK11A cyclin-dependent kinase 11A 2.20017
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2.19867
CYB5R2 cytochrome b5 reductase 2 2.19673
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 2.1887
RAP1B RAP1B, member of RAS oncogene family 2.18628
EGR4 early growth response 4 2.17339
STAU1 staufen double-stranded RNA binding protein 1 2.1712
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.1705
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.16269
FST follistatin 2.1609
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 2.15377
NR4A2 nuclear receptor subfamily 4, group A, member 2 2.15336
H2AC4 H2A clustered histone 4 2.15037
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 2.14943
ING1 inhibitor of growth family, member 1 2.14602
CD24 CD24 molecule 2.14515
FOSL1 FOS-like antigen 1 2.14307
COL5A3 collagen, type V, alpha 3 2.14177
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.14089
USP11 ubiquitin specific peptidase 11 2.1396
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 2.13083
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.13056
MEX3C mex-3 RNA binding family member C 2.12895
TSPYL2 TSPY-like 2 2.12826
TFRC transferrin receptor 2.12567
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.11977
NUPR1 nuclear protein, transcriptional regulator, 1 2.1194
PTBP2 polypyrimidine tract binding protein 2 2.11784
EIF5 eukaryotic translation initiation factor 5 2.11657
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.11515
GPATCH8 G patch domain containing 8 2.11393
SLC35F5 solute carrier family 35, member F5 2.11173
KRT34 keratin 34, type I 2.11116
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.10848
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 2.10031
BIN3 bridging integrator 3 2.09858
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 2.09277
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.09054
GLRX2 glutaredoxin 2 2.085
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 2.0842
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 2.08416
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.08349
FXR1 fragile X mental retardation, autosomal homolog 1 2.07873
TUBB2B tubulin, beta 2B class IIb 2.07265
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 2.07079
STIP1 stress-induced phosphoprotein 1 2.06295
MAP2K3 mitogen-activated protein kinase kinase 3 2.06286
HCFC2 host cell factor C2 2.06075
GSDMB gasdermin B 2.06058
ARMCX3 armadillo repeat containing, X-linked 3 2.05821
SMTN smoothelin 2.05646
PTHLH parathyroid hormone-like hormone 2.05641
MMP9 matrix metallopeptidase 9 2.05463
CARS1 cysteinyl-tRNA synthetase 1 2.05283
MUTYH mutY homolog 2.05135
SEC24A SEC24 family member A 2.04946
RNPS1 RNA binding protein S1, serine-rich domain 2.04866
CGGBP1 CGG triplet repeat binding protein 1 2.0475
RSRC2 arginine/serine-rich coiled-coil 2 2.04699
TBX3 T-box 3 2.04423
H2AC19 H2A clustered histone 19 2.04389
TOR1AIP2 torsin A interacting protein 2 2.04333
PANX1 pannexin 1 2.04048
ZFAND3 zinc finger, AN1-type domain 3 2.03913
ZBTB17 zinc finger and BTB domain containing 17 2.03662
LYN LYN proto-oncogene, Src family tyrosine kinase 2.03489
EBNA1BP2 EBNA1 binding protein 2 2.03444
ZNF821 zinc finger protein 821 2.03082
CDC25A cell division cycle 25A 2.02907
GADD45G growth arrest and DNA-damage-inducible, gamma 2.02821
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.02732
WWC2 WW and C2 domain containing 2 2.02726
SCAND1 SCAN domain containing 1 2.0233
ZNF410 zinc finger protein 410 2.02242
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.02191
SLC38A12 solute carrier family 38 member 12 2.02063
TWIST1 twist family bHLH transcription factor 1 2.01704
RND3 Rho family GTPase 3 2.01609
SPINK1 serine peptidase inhibitor, Kazal type 1 2.00527

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -6.42222
ANKRD10 ankyrin repeat domain 10 -5.99032
CPNE3 copine III -5.98295
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -5.88555
PGM1 phosphoglucomutase 1 -5.61245
TSPAN6 tetraspanin 6 -5.42253
SESN1 sestrin 1 -5.23942
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -5.20174
ADI1 acireductone dioxygenase 1 -4.91107
TMEM187 transmembrane protein 187 -4.87981
BLCAP bladder cancer associated protein -4.8782
B4GAT1 beta-1,4-glucuronyltransferase 1 -4.87522
DNM1L dynamin 1-like -4.77624
PPA2 pyrophosphatase (inorganic) 2 -4.75255
DDIT4 DNA-damage-inducible transcript 4 -4.71429
MRPS2 mitochondrial ribosomal protein S2 -4.65958
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.56804
AP5M1 adaptor-related protein complex 5, mu 1 subunit -4.46962
TSEN2 TSEN2 tRNA splicing endonuclease subunit -4.39667
NISCH nischarin -4.35634
CD58 CD58 molecule -4.32046
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.2444
CISD1 CDGSH iron sulfur domain 1 -4.19108
TCEA2 transcription elongation factor A (SII), 2 -4.19058
SLC35A5 solute carrier family 35, member A5 -4.16588
SHPK sedoheptulokinase -4.12518
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -4.06371
FKTN fukutin -4.0615
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -4.03581
HADH hydroxyacyl-CoA dehydrogenase -4.02705
ELOVL6 ELOVL fatty acid elongase 6 -4.00299
RHOT1 ras homolog family member T1 -3.92732
SYNE2 spectrin repeat containing, nuclear envelope 2 -3.90559
COG2 component of oligomeric golgi complex 2 -3.88151
ZMYM3 zinc finger, MYM-type 3 -3.87383
LOC112694756 uncharaterized LOC112694756 -3.86284
INSIG1 insulin induced gene 1 -3.85001
BACE2 beta-site APP-cleaving enzyme 2 -3.84486
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.83966
PPP1R26 protein phosphatase 1, regulatory subunit 26 -3.78892
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -3.78723
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.78399
ICE2 interactor of little elongation complex ELL subunit 2 -3.77817
TCTA T-cell leukemia translocation altered -3.76815
EXTL2 exostosin-like glycosyltransferase 2 -3.76354
PRKX protein kinase, X-linked -3.7058
THTPA thiamine triphosphatase -3.70263
METTL8 methyltransferase like 8 -3.68764
TMEM43 transmembrane protein 43 -3.68488
SYPL1 synaptophysin-like 1 -3.67487
HOXA5 homeobox A5 -3.67113
DENND2D DENN/MADD domain containing 2D -3.65598
NCSTN nicastrin -3.65431
TIPRL TOR signaling pathway regulator -3.65346
PRCP prolylcarboxypeptidase (angiotensinase C) -3.64877
AUH AU RNA binding protein/enoyl-CoA hydratase -3.64416
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -3.62823
COQ4 coenzyme Q4 -3.61807
TOP2A topoisomerase (DNA) II alpha 170kDa -3.6086
ANAPC1 anaphase promoting complex subunit 1 -3.5654
HMGN4 high mobility group nucleosomal binding domain 4 -3.56509
C1GALT1C1 C1GALT1-specific chaperone 1 -3.56316
MGST3 microsomal glutathione S-transferase 3 -3.51648
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -3.51373
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) -3.49441
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -3.48735
NNT nicotinamide nucleotide transhydrogenase -3.47821
PSRC1 proline/serine-rich coiled-coil 1 -3.46436
S100A4 S100 calcium binding protein A4 -3.46139
TASOR transcription activation suppressor -3.45716
DCK deoxycytidine kinase -3.45622
MRS2 MRS2 magnesium transporter -3.45254
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.4336
PALB2 partner and localizer of BRCA2 -3.42889
RESF1 retroelement silencing factor 1 -3.42839
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -3.42653
TTC19 tetratricopeptide repeat domain 19 -3.4253
NHLRC2 NHL repeat containing 2 -3.41079
CDK20 cyclin-dependent kinase 20 -3.40883
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -3.40372
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -3.39873
BRD3 bromodomain containing 3 -3.39613
TSC22D3 TSC22 domain family, member 3 -3.39331
NPDC1 neural proliferation, differentiation and control, 1 -3.38752
PEX11B peroxisomal biogenesis factor 11 beta -3.3773
GTF2A2 general transcription factor IIA, 2, 12kDa -3.3715
ALG6 ALG6, alpha-1,3-glucosyltransferase -3.36356
THEM6 thioesterase superfamily member 6 -3.35904
HEATR1 HEAT repeat containing 1 -3.34422
PDHB pyruvate dehydrogenase (lipoamide) beta -3.33153
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.32562
TMEM168 transmembrane protein 168 -3.32393
SPAG7 sperm associated antigen 7 -3.3227
SPTBN2 spectrin, beta, non-erythrocytic 2 -3.3184
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -3.31803
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -3.31412
TMEM80 transmembrane protein 80 -3.29522
SCGB1D1 secretoglobin, family 1D, member 1 -3.29028
CDK4 cyclin-dependent kinase 4 -3.28895
SLC35F2 solute carrier family 35, member F2 -3.28565
GET1 guided entry of tail-anchored proteins factor 1 -3.28179
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.27869
GTPBP8 GTP-binding protein 8 (putative) -3.27195
POLR2M polymerase (RNA) II (DNA directed) polypeptide M -3.25374
FBXO34 F-box protein 34 -3.24963
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -3.24518
CRYZ crystallin, zeta (quinone reductase) -3.23914
CRTAP cartilage associated protein -3.23875
PRR15L proline rich 15-like -3.2239
LBR lamin B receptor -3.22216
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -3.21944
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -3.21672
SPPL2A signal peptide peptidase like 2A -3.21238
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.20248
KRCC1 lysine-rich coiled-coil 1 -3.20226
HSDL2 hydroxysteroid dehydrogenase like 2 -3.19837
DHRS1 dehydrogenase/reductase (SDR family) member 1 -3.17513
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -3.1748
ZDHHC6 zinc finger, DHHC-type containing 6 -3.1747
PROS1 protein S (alpha) -3.17203
CCNB2 cyclin B2 -3.14454
UBAC1 UBA domain containing 1 -3.14083
AKAP11 A kinase (PRKA) anchor protein 11 -3.14076
PCCB propionyl CoA carboxylase, beta polypeptide -3.13887
FASTKD1 FAST kinase domains 1 -3.13355
FPGS folylpolyglutamate synthase -3.12097
TRIM22 tripartite motif containing 22 -3.11689
GMPR2 guanosine monophosphate reductase 2 -3.10507
POGLUT1 protein O-glucosyltransferase 1 -3.1011
CAPN2 calpain 2, (m/II) large subunit -3.09624
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -3.09389
PCYOX1L prenylcysteine oxidase 1 like -3.09095
MKKS McKusick-Kaufman syndrome -3.08854
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -3.08535
RMI1 RecQ mediated genome instability 1 -3.08457
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.083
TP53 tumor protein p53 -3.08271
TMX1 thioredoxin-related transmembrane protein 1 -3.08245
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -3.08111
SREBF1 sterol regulatory element binding transcription factor 1 -3.07398
LDHD lactate dehydrogenase D -3.07317
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -3.06968
ANXA7 annexin A7 -3.06716
SUOX sulfite oxidase -3.06368
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.06195
CAAP1 caspase activity and apoptosis inhibitor 1 -3.05897
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -3.04294
INPP1 inositol polyphosphate-1-phosphatase -3.04158
ZMYM1 zinc finger, MYM-type 1 -3.04098
PLS1 plastin 1 -3.02595
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -3.02185
SKP1 S-phase kinase-associated protein 1 -3.01173
BTN3A1 butyrophilin, subfamily 3, member A1 -3.01053
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 -3.00307
ABHD14A abhydrolase domain containing 14A -2.99744
FAM20B family with sequence similarity 20, member B -2.99601
UBXN2B UBX domain protein 2B -2.99407
DERA deoxyribose-phosphate aldolase (putative) -2.98782
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.97521
BBS1 Bardet-Biedl syndrome 1 -2.97004
CKAP2 cytoskeleton associated protein 2 -2.96909
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.96393
BARX2 BARX homeobox 2 -2.96118
RABEPK Rab9 effector protein with kelch motifs -2.95224
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.94874
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.94807
EXD2 exonuclease 3'-5' domain containing 2 -2.93924
PANK3 pantothenate kinase 3 -2.93698
DPYD dihydropyrimidine dehydrogenase -2.93116
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.92651
KYAT3 kynurenine aminotransferase 3 -2.92643
STAU2 staufen double-stranded RNA binding protein 2 -2.91544
PYGL phosphorylase, glycogen, liver -2.90951
EPHA1 EPH receptor A1 -2.89859
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -2.89597
RABL6 RAB, member RAS oncogene family-like 6 -2.89529
RBL2 retinoblastoma-like 2 -2.89221
CD46 CD46 molecule, complement regulatory protein -2.8867
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.88302
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.88183
KHDC4 KH domain containing 4, pre-mRNA splicing factor -2.88119
RPA3 replication protein A3, 14kDa -2.87525
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.86709
MECR mitochondrial trans-2-enoyl-CoA reductase -2.86124
FASTKD3 FAST kinase domains 3 -2.86066
SPTSSA serine palmitoyltransferase, small subunit A -2.85459
DPP8 dipeptidyl-peptidase 8 -2.85359
MBTPS1 membrane-bound transcription factor peptidase, site 1 -2.84529
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.84527
KYAT1 kynurenine aminotransferase 1 -2.84217
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.84092
SLC25A46 solute carrier family 25, member 46 -2.83475
SRP9 signal recognition particle 9kDa -2.82294
MPZL2 myelin protein zero-like 2 -2.82246
TKT transketolase -2.82074
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -2.8135
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.81187
NIPSNAP2 nipsnap homolog 2 -2.81024
FASN fatty acid synthase -2.80296
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.7965
MDH1 malate dehydrogenase 1, NAD (soluble) -2.79254
SLC38A10 solute carrier family 38, member 10 -2.78921
COMMD10 COMM domain containing 10 -2.78861
RNF103-CHMP3 RNF103-CHMP3 readthrough -2.78639
ERMP1 endoplasmic reticulum metallopeptidase 1 -2.78381
ASB13 ankyrin repeat and SOCS box containing 13 -2.77017
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.76694
UBE3C ubiquitin protein ligase E3C -2.76529
APOO apolipoprotein O -2.76473
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -2.76133
KLHDC2 kelch domain containing 2 -2.75666
CASP8 caspase 8, apoptosis-related cysteine peptidase -2.75593
MAT2B methionine adenosyltransferase II, beta -2.75478
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) -2.75299
TM2D1 TM2 domain containing 1 -2.74886
ZXDC ZXD family zinc finger C -2.74196
DDR1 discoidin domain receptor tyrosine kinase 1 -2.73705
RNPEP arginyl aminopeptidase (aminopeptidase B) -2.72846
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.72642
COG4 component of oligomeric golgi complex 4 -2.71978
PMPCA peptidase (mitochondrial processing) alpha -2.71856
UNC50 unc-50 homolog (C. elegans) -2.717
MRPS14 mitochondrial ribosomal protein S14 -2.71665
TXNDC9 thioredoxin domain containing 9 -2.71589
ATRAID all-trans retinoic acid-induced differentiation factor -2.71367
BTN3A2 butyrophilin, subfamily 3, member A2 -2.70781
FHIT fragile histidine triad -2.70657
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.7063
PIGG phosphatidylinositol glycan anchor biosynthesis, class G -2.70259
GSTK1 glutathione S-transferase kappa 1 -2.70188
DLAT dihydrolipoamide S-acetyltransferase -2.6961
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -2.69263
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.69027
TMEM165 transmembrane protein 165 -2.68515
ENTR1 endosome associated trafficking regulator 1 -2.67982
BST2 bone marrow stromal cell antigen 2 -2.67943
IQGAP1 IQ motif containing GTPase activating protein 1 -2.67518
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -2.67151
SKAP2 src kinase associated phosphoprotein 2 -2.66837
TCTN1 tectonic family member 1 -2.66663
CD320 CD320 molecule -2.66213
MOAP1 modulator of apoptosis 1 -2.66128
SINHCAF SIN3-HDAC complex associated factor -2.65946
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -2.65335
MYO5C myosin VC -2.64985
PRRC2B proline-rich coiled-coil 2B -2.64593
BSPRY B-box and SPRY domain containing -2.64554
SELENOF selenoprotein F -2.6435
TZMP1 transition zone microprotein 1 -2.64271
SKIC8 SKI8 subunit of superkiller complex -2.64111
PHKB phosphorylase kinase, beta -2.63846
TUBGCP4 tubulin, gamma complex associated protein 4 -2.63459
ARL17B ADP-ribosylation factor-like 17B -2.63158
PARPBP PARP1 binding protein -2.62834
ABITRAM actin binding transcription modulator -2.62081
MINDY1 MINDY lysine 48 deubiquitinase 1 -2.61847
LY6E lymphocyte antigen 6 complex, locus E -2.6165
GFUS GDP-L-fucose synthase -2.61573
TRAP1 TNF receptor-associated protein 1 -2.61557
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -2.61404
SSBP2 single-stranded DNA binding protein 2 -2.60927
SSNA1 Sjogren syndrome nuclear autoantigen 1 -2.6059
ADGRE5 adhesion G protein-coupled receptor E5 -2.6058
CDK1 cyclin-dependent kinase 1 -2.60057
ZNF451 zinc finger protein 451 -2.59665
TMEM106B transmembrane protein 106B -2.59475
RNF170 ring finger protein 170 -2.59424
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.59054
DSG2 desmoglein 2 -2.58968
SGMS1 sphingomyelin synthase 1 -2.58616
CD33 CD33 molecule -2.58023
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -2.57474
SLC41A3 solute carrier family 41, member 3 -2.57264
PUM2 pumilio RNA-binding family member 2 -2.56697
SORT1 sortilin 1 -2.56562
ATMIN ATM interactor -2.563
SCARB1 scavenger receptor class B, member 1 -2.56213
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -2.5613
TMEM126B transmembrane protein 126B -2.55286
RSU1 Ras suppressor protein 1 -2.54506
ST20-MTHFS ST20-MTHFS readthrough -2.54327
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.53242
ABHD18 abhydrolase domain containing 18 -2.53195
PEX19 peroxisomal biogenesis factor 19 -2.52632
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 -2.52448
ZNF33B zinc finger protein 33B -2.52299
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -2.52067
DNAAF5 dynein, axonemal, assembly factor 5 -2.52048
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.51933
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -2.51853
TMEM186 transmembrane protein 186 -2.51851
SCAMP1 secretory carrier membrane protein 1 -2.5169
UBA3 ubiquitin-like modifier activating enzyme 3 -2.51283
IRX4 iroquois homeobox 4 -2.5087
PFAS phosphoribosylformylglycinamidine synthase -2.50765
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.5049
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 -2.50474
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.50229
UROS uroporphyrinogen III synthase -2.50114
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -2.49874
MGST2 microsomal glutathione S-transferase 2 -2.49443
PRMT3 protein arginine methyltransferase 3 -2.49293
TM9SF1 transmembrane 9 superfamily member 1 -2.49109
FAM216A family with sequence similarity 216, member A -2.48695
ENDOG endonuclease G -2.48192
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) -2.47947
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.47906
TMCO1 transmembrane and coiled-coil domains 1 -2.47707
ACYP2 acylphosphatase 2, muscle type -2.47454
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.47144
CTNNBIP1 catenin, beta interacting protein 1 -2.47112
TSKU tsukushi, small leucine rich proteoglycan -2.47105
DOCK1 dedicator of cytokinesis 1 -2.47008
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -2.46971
RPAP2 RNA polymerase II associated protein 2 -2.465
GOLPH3L golgi phosphoprotein 3-like -2.46347
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -2.46123
NIT2 nitrilase family, member 2 -2.45707
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -2.45699
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -2.44876
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -2.44855
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.44663
VPS35L VPS35 endosomal protein sorting factor like -2.44572
NMI N-myc (and STAT) interactor -2.44499
NIPAL2 NIPA-like domain containing 2 -2.44076
CCDC51 coiled-coil domain containing 51 -2.43948
VAMP7 vesicle-associated membrane protein 7 -2.43751
SH3D19 SH3 domain containing 19 -2.43641
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -2.43625
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.43592
DMAC2L distal membrane arm assembly component 2 like -2.42877
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -2.4255
PARG poly (ADP-ribose) glycohydrolase -2.42383
TFEC transcription factor EC -2.42237
NAAA N-acylethanolamine acid amidase -2.42077
NUP42 nucleoporin 42 -2.4185
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.41479
COXFA4 cytochrome c oxidase associated subunit FA4 -2.41325
BACE1 beta-site APP-cleaving enzyme 1 -2.41034
ZBED5 zinc finger, BED-type containing 5 -2.40872
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -2.40537
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.40472
VWA8 von Willebrand factor A domain containing 8 -2.40436
ANKRD17 ankyrin repeat domain 17 -2.4027
AKAP10 A kinase (PRKA) anchor protein 10 -2.4021
ARB2A ARB2 cotranscriptional regulator A -2.40137
PISD phosphatidylserine decarboxylase -2.39754
TRIM27 tripartite motif containing 27 -2.39427
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.39419
MRPL3 mitochondrial ribosomal protein L3 -2.39313
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 -2.39243
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -2.39176
OXA1L oxidase (cytochrome c) assembly 1-like -2.38628
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.38592
DEAF1 DEAF1 transcription factor -2.38526
LARS1 leucyl-tRNA synthetase 1 -2.38328
TRAPPC13 trafficking protein particle complex 13 -2.38241
BPIFA1 BPI fold containing family A, member 1 -2.38199
HYAL2 hyaluronoglucosaminidase 2 -2.38181
SH3YL1 SH3 and SYLF domain containing 1 -2.38155
ABHD10 abhydrolase domain containing 10 -2.37701
UNC45A unc-45 homolog A (C. elegans) -2.37307
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.37106
HOXB3 homeobox B3 -2.37076
DET1 de-etiolated homolog 1 (Arabidopsis) -2.36992
NAT10 N-acetyltransferase 10 (GCN5-related) -2.36927
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -2.36826
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -2.36458
TRMT61B tRNA methyltransferase 61B -2.36422
CCNG1 cyclin G1 -2.36378
BBS10 Bardet-Biedl syndrome 10 -2.36274
PIKFYVE phosphoinositide kinase, FYVE finger containing -2.36235
DNM1 dynamin 1 -2.35972
TRAK2 trafficking protein, kinesin binding 2 -2.3589
TFB1M transcription factor B1, mitochondrial -2.35878
VBP1 von Hippel-Lindau binding protein 1 -2.35702
PEX3 peroxisomal biogenesis factor 3 -2.35648
TMEM267 transmembrane protein 267 -2.35521
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -2.35496
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.35163
PRDX3 peroxiredoxin 3 -2.34466
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.34351
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -2.34079
NUP43 nucleoporin 43kDa -2.34057
CD47 CD47 molecule -2.3396
SKIC3 SKI3 subunit of superkiller complex -2.3349
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 -2.33154
CHL1 cell adhesion molecule L1-like -2.32969
RIDA reactive intermediate imine deaminase A homolog -2.32879
KIF14 kinesin family member 14 -2.32261
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -2.32117
FAN1 FANCD2/FANCI-associated nuclease 1 -2.32007
C2CD5 C2 calcium-dependent domain containing 5 -2.31841
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -2.31745
ERGIC2 ERGIC and golgi 2 -2.31688
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.31623
COASY CoA synthase -2.31485
PCYOX1 prenylcysteine oxidase 1 -2.31187
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.30954
ZNF274 zinc finger protein 274 -2.30769
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 -2.30703
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -2.30479
MTREX Mtr4 exosome RNA helicase -2.30408
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.30242
ADSS2 adenylosuccinate synthase 2 -2.30237
ZNF623 zinc finger protein 623 -2.30216
MAPKAP1 mitogen-activated protein kinase associated protein 1 -2.29905
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -2.29721
RBM47 RNA binding motif protein 47 -2.29721
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.29516
UNC13B unc-13 homolog B (C. elegans) -2.29082
PTAFR platelet-activating factor receptor -2.29058
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 -2.29028
PRKCD protein kinase C, delta -2.28987
MRTFB myocardin related transcription factor B -2.28849
SYBU syntabulin (syntaxin-interacting) -2.28685
PEX11A peroxisomal biogenesis factor 11 alpha -2.28657
ABLIM1 actin binding LIM protein 1 -2.28585
TPGS2 tubulin polyglutamylase complex subunit 2 -2.285
SMYD2 SET and MYND domain containing 2 -2.28446
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -2.28334
RPL10A ribosomal protein L10a -2.28196
RALGDS ral guanine nucleotide dissociation stimulator -2.27917
LY75-CD302 LY75-CD302 readthrough -2.27413
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like -2.27352
ISCA1 iron-sulfur cluster assembly 1 -2.27244
CXCR3 chemokine (C-X-C motif) receptor 3 -2.2722
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.27216
C1QBP complement component 1, q subcomponent binding protein -2.27171
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -2.27066
SPIN2B spindlin family, member 2B -2.26982
DPY19L4 dpy-19-like 4 (C. elegans) -2.26776
FPGT fucose-1-phosphate guanylyltransferase -2.26653
ERCC8 excision repair cross-complementation group 8 -2.26588
TMOD3 tropomodulin 3 (ubiquitous) -2.26449
CBY1 chibby homolog 1 (Drosophila) -2.2627
FAM200C family with sequence similarity 200 member C -2.26239
METTL3 methyltransferase like 3 -2.26226
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -2.26033
KLHL9 kelch-like family member 9 -2.25809
FNTA farnesyltransferase, CAAX box, alpha -2.25698
ZNF189 zinc finger protein 189 -2.25657
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -2.25629
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) -2.25609
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 -2.25304
JAG2 jagged 2 -2.25131
FBXL5 F-box and leucine-rich repeat protein 5 -2.25085
HSPB6 heat shock protein, alpha-crystallin-related, B6 -2.25074
XPO1 exportin 1 -2.24997
AKAP7 A kinase (PRKA) anchor protein 7 -2.2494
KCTD3 potassium channel tetramerization domain containing 3 -2.24466
GRHL2 grainyhead-like 2 (Drosophila) -2.24291
POGK pogo transposable element with KRAB domain -2.24106
MPZL1 myelin protein zero-like 1 -2.24062
CDC23 cell division cycle 23 -2.2355
DCPH1 damage control phosphatase 1 -2.23441
TMEM33 transmembrane protein 33 -2.23383
BGLAP bone gamma-carboxyglutamate (gla) protein -2.23263
KATNBL1 katanin p80 subunit B-like 1 -2.23067
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -2.22878
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.22765
LOC128966570 alpha-amylase 1B -2.22535
GSTP1 glutathione S-transferase pi 1 -2.22337
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.22229
SLC25A40 solute carrier family 25, member 40 -2.22186
USP19 ubiquitin specific peptidase 19 -2.2211
KRT24 keratin 24, type I -2.21903
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -2.21837
NCAPD3 non-SMC condensin II complex, subunit D3 -2.21682
MAB21L4 mab-21 like 4 -2.21589
MYO9A myosin IXA -2.20885
PIGO phosphatidylinositol glycan anchor biosynthesis, class O -2.2046
WDR77 WD repeat domain 77 -2.20442
ATG3 autophagy related 3 -2.20333
CUL4A cullin 4A -2.20264
PRPF4 pre-mRNA processing factor 4 -2.20052
PLA2G12A phospholipase A2, group XIIA -2.19924
SP8 Sp8 transcription factor -2.1988
AGK acylglycerol kinase -2.19737
RPS5 ribosomal protein S5 -2.19397
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.19134
FKBP5 FK506 binding protein 5 -2.19081
MAPK9 mitogen-activated protein kinase 9 -2.19064
FANCF Fanconi anemia, complementation group F -2.18898
CETN2 centrin, EF-hand protein, 2 -2.18747
BTBD1 BTB (POZ) domain containing 1 -2.18556
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 -2.18517
RSRP1 arginine/serine-rich protein 1 -2.1828
KIF1B kinesin family member 1B -2.18245
MRPL12 mitochondrial ribosomal protein L12 -2.18222
IARS1 isoleucyl-tRNA synthetase 1 -2.18081
COX11 COX11 cytochrome c oxidase copper chaperone -2.18043
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -2.1797
RXRA retinoid X receptor, alpha -2.17941
SNX4 sorting nexin 4 -2.17925
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.17227
FAT2 FAT atypical cadherin 2 -2.1687
CSK c-src tyrosine kinase -2.16812
CIDEB cell death-inducing DFFA-like effector b -2.16808
BRD3OS BRD3 opposite strand -2.16226
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -2.1615
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.16032
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -2.1603
WASHC4 WASH complex subunit 4 -2.15692
GRN granulin -2.15618
HDAC2 histone deacetylase 2 -2.15605
GATD3 glutamine amidotransferase class 1 domain containing 3 -2.15513
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.15438
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 -2.15288
MPHOSPH9 M-phase phosphoprotein 9 -2.15265
CNTRL centriolin -2.1486
R3HDM2 R3H domain containing 2 -2.14825
RYK receptor-like tyrosine kinase -2.14762
ZNF587B zinc finger protein 587B -2.14677
SMC1A structural maintenance of chromosomes 1A -2.14511
MYCBP MYC binding protein -2.14429
COG7 component of oligomeric golgi complex 7 -2.14035
EFR3A EFR3 homolog A (S. cerevisiae) -2.13918
CPT2 carnitine palmitoyltransferase 2 -2.13775
ATP10D ATPase, class V, type 10D -2.13675
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -2.13436
FHL5 four and a half LIM domains 5 -2.13391
CRYL1 crystallin, lambda 1 -2.13324
DOLK dolichol kinase -2.13242
RAB33B RAB33B, member RAS oncogene family -2.13186
ZNF318 zinc finger protein 318 -2.13121
FBXL2 F-box and leucine-rich repeat protein 2 -2.12934
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -2.12924
LPCAT3 lysophosphatidylcholine acyltransferase 3 -2.1292
SAMHD1 SAM domain and HD domain 1 -2.12916
PLSCR1 phospholipid scramblase 1 -2.12881
GLB1 galactosidase, beta 1 -2.12846
AP3M2 adaptor-related protein complex 3, mu 2 subunit -2.12837
SLC35E2B solute carrier family 35, member E2B -2.12824
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -2.12522
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -2.12312
FAM120A family with sequence similarity 120A -2.12205
ATP5PB ATP synthase peripheral stalk-membrane subunit b -2.12126
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -2.11933
PLAC8 placenta-specific 8 -2.11777
CBR4 carbonyl reductase 4 -2.11551
MICU2 mitochondrial calcium uptake 2 -2.11536
CYFIP1 cytoplasmic FMR1 interacting protein 1 -2.11536
ELP4 elongator acetyltransferase complex subunit 4 -2.11444
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -2.11368
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 -2.1124
PGRMC2 progesterone receptor membrane component 2 -2.11202
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -2.11197
ASF1A anti-silencing function 1A histone chaperone -2.11132
COMMD8 COMM domain containing 8 -2.10694
NUP133 nucleoporin 133kDa -2.10517
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.10341
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.10306
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -2.10246
SLC46A3 solute carrier family 46, member 3 -2.10159
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.10142
ZDHHC4 zinc finger, DHHC-type containing 4 -2.09996
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.09801
WASF3 WAS protein family, member 3 -2.09797
SECISBP2 SECIS binding protein 2 -2.09701
RBKS ribokinase -2.09599
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.09549
DCAF8 DDB1 and CUL4 associated factor 8 -2.09533
ANKRD46 ankyrin repeat domain 46 -2.09498
GTF2IRD2B GTF2I repeat domain containing 2B -2.09469
LDAH lipid droplet associated hydrolase -2.09384
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.09352
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -2.0929
PITX1 paired-like homeodomain 1 -2.09264
RAB4A RAB4A, member RAS oncogene family -2.08826
GCA grancalcin, EF-hand calcium binding protein -2.08709
INTS7 integrator complex subunit 7 -2.0846
DCAF10 DDB1 and CUL4 associated factor 10 -2.0842
DCAF6 DDB1 and CUL4 associated factor 6 -2.08322
ZNF514 zinc finger protein 514 -2.08097
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -2.07989
PTCD3 pentatricopeptide repeat domain 3 -2.07968
PRMT2 protein arginine methyltransferase 2 -2.0778
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.07494
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -2.07393
GLOD4 glyoxalase domain containing 4 -2.0707
TMEM183A transmembrane protein 183A -2.06974
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.06815
ATRIP ATR interacting protein -2.06507
TSPAN14 tetraspanin 14 -2.06243
RNF14 ring finger protein 14 -2.06186
RUSC1 RUN and SH3 domain containing 1 -2.05875
FKBP3 FK506 binding protein 3, 25kDa -2.05853
CLEC7A C-type lectin domain family 7, member A -2.05849
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -2.05831
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.05421
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -2.05261
RAB20 RAB20, member RAS oncogene family -2.05259
ZNF248 zinc finger protein 248 -2.05232
PRUNE1 prune exopolyphosphatase 1 -2.05231
MED21 mediator complex subunit 21 -2.05215
THOC7 THO complex 7 -2.04985
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -2.0496
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.04785
ARHGAP15 Rho GTPase activating protein 15 -2.04575
ADRA2C adrenoceptor alpha 2C -2.04569
RNF130 ring finger protein 130 -2.04486
STEAP4 STEAP family member 4 -2.04442
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.04432
GSTA4 glutathione S-transferase alpha 4 -2.03992
XPC xeroderma pigmentosum, complementation group C -2.03955
LPCAT4 lysophosphatidylcholine acyltransferase 4 -2.03741
OSMR oncostatin M receptor -2.03679
TUFM Tu translation elongation factor, mitochondrial -2.03599
ZFYVE21 zinc finger, FYVE domain containing 21 -2.03545
HACL2 2-hydroxyacyl-CoA lyase 2 -2.03534
ZNF721 zinc finger protein 721 -2.03125
LRRC61 leucine rich repeat containing 61 -2.03066
JADE2 jade family PHD finger 2 -2.03
CCDC25 coiled-coil domain containing 25 -2.0284
DEXI Dexi homolog (mouse) -2.02781
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.02753
TUBGCP5 tubulin, gamma complex associated protein 5 -2.02663
SEC23A Sec23 homolog A (S. cerevisiae) -2.02413
CENPI centromere protein I -2.02307
GRWD1 glutamate-rich WD repeat containing 1 -2.02281
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.02262
VPS26C VPS26 endosomal protein sorting factor C -2.02207
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -2.01845
ZNF529 zinc finger protein 529 -2.01715
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -2.01467
UGP2 UDP-glucose pyrophosphorylase 2 -2.01452
ICAM3 intercellular adhesion molecule 3 -2.01347
ETFB electron-transfer-flavoprotein, beta polypeptide -2.01106
CPVL carboxypeptidase, vitellogenic-like -2.01009
DPH2 DPH2 homolog (S. cerevisiae) -2.00865
TMEM14B transmembrane protein 14B -2.0077
ZDHHC13 zinc finger, DHHC-type containing 13 -2.00734
PRKCH protein kinase C, eta -2.006
RABIF RAB interacting factor -2.00505
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.00364
ZFAND1 zinc finger, AN1-type domain 1 -2.00157
SREBF2 sterol regulatory element binding transcription factor 2 -2.00045