CRCGN016_MCF10A.TP53.M_24H:F15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description thiram 11.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TOMM34 translocase of outer mitochondrial membrane 34 3.99039
RPL39L ribosomal protein L39-like 3.82656
IL1B interleukin 1, beta 3.24927
SNX11 sorting nexin 11 3.12308
OXSR1 oxidative stress responsive 1 3.06664
EAPP E2F-associated phosphoprotein 3.04853
ACAA1 acetyl-CoA acyltransferase 1 2.97063
AGR2 anterior gradient 2 2.82826
EML3 echinoderm microtubule associated protein like 3 2.73855
IDE insulin-degrading enzyme 2.65203
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.41767
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.35496
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.14687
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.06809
ICAM3 intercellular adhesion molecule 3 2.02696
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.02215
PKN1 protein kinase N1 2.01148

decreased expression

Symbol Name Standardized Value
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -5.49999
ANKRD10 ankyrin repeat domain 10 -3.60845
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.51958
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.1544
DYNLT3 dynein, light chain, Tctex-type 3 -3.0834
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.80669
KIF14 kinesin family member 14 -2.75098
ENOPH1 enolase-phosphatase 1 -2.68295
ELAC2 elaC ribonuclease Z 2 -2.61401
ZMYM2 zinc finger, MYM-type 2 -2.55129
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.38795
WASHC4 WASH complex subunit 4 -2.30011
GRN granulin -2.09398
CPA1 carboxypeptidase A1 (pancreatic) -2.05848
DRAM1 DNA-damage regulated autophagy modulator 1 -2.03105
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -2.01867