CRCGN016_MCF10A.TP53.M_24H:F16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description BRD-K88965984 100.97 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ANO10 anoctamin 10 3.87774
ACAA1 acetyl-CoA acyltransferase 1 3.2994
HBA1 hemoglobin, alpha 1 2.82837
CCP110 centriolar coiled coil protein 110kDa 2.79459
STIMATE STIM activating enhancer 2.75635
CXCL2 chemokine (C-X-C motif) ligand 2 2.72467
SNAP25 synaptosomal-associated protein, 25kDa 2.587
PTPRK protein tyrosine phosphatase, receptor type, K 2.48516
WIF1 WNT inhibitory factor 1 2.34694
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.32512
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.03739

decreased expression

Symbol Name Standardized Value
STXBP2 syntaxin binding protein 2 -3.68662
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.45024
HSPA8 heat shock 70kDa protein 8 -2.9397
GRWD1 glutamate-rich WD repeat containing 1 -2.88221
CDC20 cell division cycle 20 -2.81501
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 -2.31289
ETFB electron-transfer-flavoprotein, beta polypeptide -2.20019
VAT1 vesicle amine transport 1 -2.18754
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.04368
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.00346