| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | BRD-K88965984 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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53 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.88479 |
| EAPP | E2F-associated phosphoprotein | 3.55965 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 3.31163 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.92595 |
| SRP54 | signal recognition particle 54kDa | 2.80457 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 2.77606 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.66651 |
| MELK | maternal embryonic leucine zipper kinase | 2.64426 |
| STK10 | serine/threonine kinase 10 | 2.56235 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 2.45808 |
| ACBD3 | acyl-CoA binding domain containing 3 | 2.3883 |
| KAT6B | K(lysine) acetyltransferase 6B | 2.3773 |
| FGFR4 | fibroblast growth factor receptor 4 | 2.3379 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.26709 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 2.25299 |
| TSNAX | translin-associated factor X | 2.1776 |
| TENT5A | terminal nucleotidyltransferase 5A | 2.16939 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | 2.16483 |
| TBX2 | T-box 2 | 2.1272 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 2.09167 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 2.07045 |
| LSP1 | lymphocyte-specific protein 1 | 2.02174 |
| DOCK2 | dedicator of cytokinesis 2 | 2.00815 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TES | testin LIM domain protein | -3.47891 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.25125 |
| KIF20A | kinesin family member 20A | -3.18149 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.0912 |
| TRAPPC3 | trafficking protein particle complex 3 | -3.04625 |
| TKT | transketolase | -2.93818 |
| VDAC1 | voltage-dependent anion channel 1 | -2.85287 |
| CDC20 | cell division cycle 20 | -2.83486 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.82748 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -2.74162 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -2.69778 |
| PAEP | progestagen-associated endometrial protein | -2.53888 |
| CANT1 | calcium activated nucleotidase 1 | -2.49216 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.45982 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -2.43126 |
| DUSP14 | dual specificity phosphatase 14 | -2.41306 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.40192 |
| MRPS15 | mitochondrial ribosomal protein S15 | -2.39273 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.33206 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 | -2.33108 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.32889 |
| SF3A3 | splicing factor 3a, subunit 3, 60kDa | -2.25071 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.18416 |
| FHIT | fragile histidine triad | -2.17085 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 | -2.11943 |
| ETFDH | electron-transferring-flavoprotein dehydrogenase | -2.10759 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | -2.0421 |
| INHBB | inhibin, beta B | -2.0394 |
| MAP7D1 | MAP7 domain containing 1 | -2.02233 |
| MEF2B | myocyte enhancer factor 2B | -2.00464 |
