CRCGN016_MCF10A.TP53.M_24H:F19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo(a)pyrene 96.93 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

26 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
VAV3 vav 3 guanine nucleotide exchange factor 3.31001
RPL39L ribosomal protein L39-like 3.07
TLR4 toll-like receptor 4 2.84148
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.75138
PFKL phosphofructokinase, liver 2.61758
WIF1 WNT inhibitory factor 1 2.53166
E2F2 E2F transcription factor 2 2.49398
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.33721
GATD3 glutamine amidotransferase class 1 domain containing 3 2.23655
CENPB centromere protein B, 80kDa 2.13031
CDC25B cell division cycle 25B 2.06456

decreased expression

Symbol Name Standardized Value
ANKRD10 ankyrin repeat domain 10 -3.95834
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.33931
NPDC1 neural proliferation, differentiation and control, 1 -3.04186
CHMP4B charged multivesicular body protein 4B -2.99078
MRPS2 mitochondrial ribosomal protein S2 -2.94823
CCDC86 coiled-coil domain containing 86 -2.93278
TEX10 testis expressed 10 -2.74739
TIMP1 TIMP metallopeptidase inhibitor 1 -2.63734
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.44601
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.34782
PAEP progestagen-associated endometrial protein -2.34781
SGK1 serum/glucocorticoid regulated kinase 1 -2.34154
NLRP4 NLR family, pyrin domain containing 4 -2.3281
REEP5 receptor accessory protein 5 -2.29962
TUBA4A tubulin, alpha 4a -2.09164