CRCGN016_MCF10A.TP53.M_24H:F20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo(a)pyrene 32.31 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 5.12788
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.98863
ABHD4 abhydrolase domain containing 4 3.10905
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.0631
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.85058
FGFR4 fibroblast growth factor receptor 4 2.80746
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.7646
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.71953
CDC25B cell division cycle 25B 2.30329
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.27581
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.15902
ACBD3 acyl-CoA binding domain containing 3 2.15602
FADD Fas (TNFRSF6)-associated via death domain 2.10226

decreased expression

Symbol Name Standardized Value
KIF20A kinesin family member 20A -5.11315
GRWD1 glutamate-rich WD repeat containing 1 -4.22962
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.75556
COTL1 coactosin-like F-actin binding protein 1 -3.4286
HMG20B high mobility group 20B -3.08855
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.74648
ATP5F1E ATP synthase F1 subunit epsilon -2.5812
CORO1A coronin, actin binding protein, 1A -2.34262
URGCP upregulator of cell proliferation -2.34097
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -2.21755
AVL9 AVL9 homolog (S. cerevisiase) -2.18327
CIDEB cell death-inducing DFFA-like effector b -2.1545
LOC107986346 mitochondrial import receptor subunit TOM7 homolog -2.14387
TRAPPC6A trafficking protein particle complex 6A -2.13481
ATP5ME ATP synthase membrane subunit e -2.0766
PIH1D1 PIH1 domain containing 1 -2.05667
GGCT gamma-glutamylcyclotransferase -2.0502